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June 2016
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Cover Image
Mitochondrial protein quality control plays a decisive role in the maintenance of a proper mitochondrial function in metabolically active tissues such as skeletal muscle. Several chaperones and proteases, involved in the regulation of mitochondrial protein quality control, are altered in obesity and type 2 diabetes mellitus. For further details see Dahlmans et al. pp. 843–852.
ISSN 0143-5221
EISSN 1470-8736
In this Issue
Review Articles
Mitochondrial dynamics, quality control and miRNA regulation in skeletal muscle: implications for obesity and related metabolic disease
Clin Sci (Lond) (2016) 130 (11): 843–852.
Frataxin and the molecular mechanism of mitochondrial iron-loading in Friedreich's ataxia
Shannon Chiang; Zaklina Kovacevic; Sumit Sahni; Darius J.R. Lane; Angelica M. Merlot; Danuta S. Kalinowski; Michael L.-H. Huang; Des R. Richardson
Clin Sci (Lond) (2016) 130 (11): 853–870.
Original Papers
High-fat diet increases O-GlcNAc levels in cerebral arteries: a link to vascular dysfunction associated with hyperlipidaemia/obesity?
Victor V. Lima; Fernanda R. Giachini; Takayuki Matsumoto; Weiguo Li; Alecsander F.M. Bressan; Dhruv Chawla; R. Clinton Webb; Adviye Ergul; Rita C. Tostes
Clin Sci (Lond) (2016) 130 (11): 871–880.
Ptp1b deletion in pro-opiomelanocortin neurons increases energy expenditure and impairs endothelial function via TNF-α dependent mechanisms
Thiago Bruder-Nascimento; Simone Kennard; Galina Antonova; James D. Mintz; Kendra K. Bence; Eric J. Belin de Chantemèle
Clin Sci (Lond) (2016) 130 (11): 881–893.
Endothelial dysfunction in DOCA-salt-hypertensive mice: role of neuronal nitric oxide synthase-derived hydrogen peroxide
Clin Sci (Lond) (2016) 130 (11): 895–906.
IL-10-producing regulatory B-cells suppressed effector T-cells but enhanced regulatory T-cells in chronic HBV infection
Yun Liu; Li-sha Cheng; Sheng-di Wu; Si-qi Wang; Lei Li; Wei-min She; Jing Li; Ji-yao Wang; Wei Jiang
Clin Sci (Lond) (2016) 130 (11): 907–919.
Promotion of tumour proliferation, migration and invasion by miR-92b in targeting RECK in osteosarcoma
Clin Sci (Lond) (2016) 130 (11): 921–930.
Mitochondrial function and glucose metabolism in the placenta with gestational diabetes mellitus: role of miR-143
Clin Sci (Lond) (2016) 130 (11): 931–941.