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April 2016
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Cover Image
Cover Image
Radiation nephropathy is mitigated by EET-A and also by captopril. The severe histological injury of radiation nephropathy includes cast formation and mesangiolysis. Both are significantly attenuated by EET-A or captopril. PAS stained kidney, 200x magnification. For further details see pp. 587–599. Image kindly provided by Dr. Md Abdul Hye Khan.
ISSN 0143-5221
EISSN 1470-8736
In this Issue
Review Articles
Women and heart disease, the underrecognized burden: sex differences, biases, and unmet clinical and research challenges
Clin Sci (Lond) (2016) 130 (8): 551–563.
Copper dyshomoeostasis in Parkinson's disease: implications for pathogenesis and indications for novel therapeutics
Clin Sci (Lond) (2016) 130 (8): 565–574.
Original Papers
Epigenetic regulation of cyclooxygenase-2 by methylation of c8orf4 in pulmonary fibrosis
Iona C. Evans; Josephine L. Barnes; Ian M. Garner; David R. Pearce; Toby M. Maher; Xu Shiwen; Elisabetta A. Renzoni; Athol U. Wells; Christopher P. Denton; Geoffrey J. Laurent; David J. Abraham; Robin J. McAnulty
Clin Sci (Lond) (2016) 130 (8): 575–586.
Epoxyeicosatrienoic acid analogue mitigates kidney injury in a rat model of radiation nephropathy
Md. Abdul Hye Khan; Brian Fish; Geneva Wahl; Amit Sharma; John R. Falck; Mahesh P. Paudyal; John E. Moulder; John D. Imig; Eric P. Cohen
Clin Sci (Lond) (2016) 130 (8): 587–599.
PAFR in adipose tissue macrophages is associated with anti-inflammatory phenotype and metabolic homoeostasis
Luciano Ribeiro Filgueiras; Marianna Mainardi Koga; Paula G. Quaresma; Edson Kiyotaka Ishizuka; Marlise B.A. Montes; Patricia O. Prada; Mario J. Saad; Sonia Jancar; Francisco J. Rios
Clin Sci (Lond) (2016) 130 (8): 601–612.
Oral oestrogen reverses ovariectomy-induced morning surge hypertension in growth-restricted mice
Sarah E. Haskell; Veronica Peotta; Benjamin E. Reinking; Catherine Zhang; Vivian Zhu; Elizabeth J. Kenkel; Robert D. Roghair
Clin Sci (Lond) (2016) 130 (8): 613–623.
Fenofibrate increases cardiac autophagy via FGF21/SIRT1 and prevents fibrosis and inflammation in the hearts of Type 1 diabetic mice
Jingjing Zhang; Yanli Cheng; Junlian Gu; Shudong Wang; Shanshan Zhou; Yuehui Wang; Yi Tan; Wenke Feng; Yaowen Fu; Nicholas Mellen; Rui Cheng; Jianxing Ma; Chi Zhang; Zhanquan Li; Lu Cai
Clin Sci (Lond) (2016) 130 (8): 625–641.