In this Issue
Chronic cerebral hypoperfusion: a key mechanism leading to vascular cognitive impairment and dementia. Closing the translational gap between rodent models and human vascular cognitive impairment and dementia
Clinical Science (1 October 2017) 131 (19): 2451–2468.
Biomarkers of disease can be detected in mice as early as 4 weeks after initiation of exposure to third-hand smoke levels equivalent to those found in homes of smokers
Clinical Science (1 October 2017) 131 (19): 2409–2426.
Genetic diagnosis of polycystic kidney disease, Alport syndrome, and thalassemia minor in a large Chinese family
Yun Miao; Jun Xiong; Xuelian Zhang; Huajie Huang; Lixin Yu; Jianfan Chen; Wenfeng Deng; Huiling Xu; Rumin Liu; Chenglin Xiang; Xiangmin Xu; Fu Xiong
Clinical Science (1 October 2017) 131 (19): 2427–2438.
Cover ImageIn this issue of Clinical Science, Thompson et al (pages 2489-2501) describe their research on the capacity of protein tyrosine phosphatase 1B inhibitor to reverse atherosclerotic plaque formation in a mouse model. The cover image shows aortic root sections of mice fed on a high-fat-diet that are stained with Oil Red - a method the authors used to quantify plaque formation in this study.