Chronic cerebral hypoperfusion: a key mechanism leading to vascular cognitive impairment and dementia. Closing the translational gap between rodent models and human vascular cognitive impairment and dementia
Clin Sci (Lond) (2017) 131 (19): 2451–2468.
Genetic diagnosis of polycystic kidney disease, Alport syndrome, and thalassemia minor in a large Chinese family
Yun Miao; Jun Xiong; Xuelian Zhang; Huajie Huang; Lixin Yu; Jianfan Chen; Wenfeng Deng; Huiling Xu; Rumin Liu; Chenglin Xiang; Xiangmin Xu; Fu Xiong
Clin Sci (Lond) (2017) 131 (19): 2427–2438.
Cover ImageIn this issue of Clinical Science, Thompson et al (pages 2489-2501) describe their research on the capacity of protein tyrosine phosphatase 1B inhibitor to reverse atherosclerotic plaque formation in a mouse model. The cover image shows aortic root sections of mice fed on a high-fat-diet that are stained with Oil Red - a method the authors used to quantify plaque formation in this study.