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Volume 133, Issue 20
October 2019
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    Growth differentiation factor (GDF) 11 has been deemed a rejuvenation factor in various studies. However, contradictory reports in its ‘rejuvenating effect’ exist. In the latest issue of Clinical Science (volume 133, issue 20), Wang et al. investigate the pathophysiological role of GDF11. Their partial hepatectomy study in mice suggest that GDF11 in fact impairs liver regeneration. This cover features a Coomassie stain analysing GDF11 protein expression.
ISSN 0143-5221
EISSN 1470-8736
In this Issue

Review Articles

Adipocyte dedifferentiation in health and diseases
Tongxing Song; Shihuan Kuang
Clin Sci (Lond) (2019) 133 (20): 2107–2119.
View Articletitled, Adipocyte dedifferentiation in health and diseases
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Hypothesis

Impaired l-arginine-nitric oxide pathway contributes to the pathogenesis of resistant hypertension
Niwanthi W. Rajapakse; Beverly Giam; Sanjaya Kuruppu; Geoffrey A. Head; David M. Kaye
Clin Sci (Lond) (2019) 133 (20): 2061–2067.
View Articletitled, Impaired <span class="small-caps">l</span>-arginine-nitric oxide pathway contributes to the pathogenesis of resistant hypertension
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Research Articles

Endogenous hydrogen sulfide sulfhydrates IKKβ at cysteine 179 to control pulmonary artery endothelial cell inflammation
Da Zhang; Xiuli Wang; Siyao Chen; Selena Chen; Wen Yu; Xin Liu; Guosheng Yang; Yinghong Tao; Xinjing Tang; Dingfang Bu; Heng Zhang; Wei Kong; Chaoshu Tang; Yaqian Huang; Junbao Du; Hongfang Jin
Clin Sci (Lond) (2019) 133 (20): 2045–2059.
View Articletitled, Endogenous hydrogen sulfide sulfhydrates IKKβ at cysteine 179 to control pulmonary artery endothelial cell inflammation
Supplementary data
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GDF11 impairs liver regeneration in mice after partial hepatectomy
Wenjie Wang; Xiao Yang; Jiankun Yang; Shenpei Liu; Yongman Lv; Cuntai Zhang; Wei Dong; Anding Liu
Clin Sci (Lond) (2019) 133 (20): 2069–2084.
View Articletitled, GDF11 impairs liver regeneration in mice after partial hepatectomy
Supplementary data
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SETD3 is regulated by a couple of microRNAs and plays opposing roles in proliferation and metastasis of hepatocellular carcinoma
Liangliang Xu; Peng Wang; Xinfu Feng; Jianwei Tang; Lian Li; Xiaobo Zheng; Jinfu Zhang; Yitao Hu; Tian Lan; Kefei Yuan; Yanfang Zhang; Shengsheng Ren; Xiangyong Hao; Ming Zhang; Mingqing Xu
Clin Sci (Lond) (2019) 133 (20): 2085–2105.
View Articletitled, SETD3 is regulated by a couple of microRNAs and plays opposing roles in proliferation and metastasis of hepatocellular carcinoma
Supplementary data
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Renal hypertrophy and hyperfiltration is enhanced in early acquired compared with a congenital solitary function kidney model in sheep
Identification of endoplasmic reticulum stress-associated lncRNAs influencing inflammation and VSMC function in abdominal aortic aneurysm
Trbp inhibits cardiac fibrosis through TGF-β pathway-mediated cross-talk between cardiomyocytes and fibroblasts
Harnessing 2D and 3D human endometrial cell culture models to investigate SARS-CoV-2 infection in early pregnancy
Persistent subclinical renal injury in female rats following renal ischemia-reperfusion injury
  • Online ISSN 1470-8736
  • Print ISSN 0143-5221

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