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Volume 133, Issue 4
February 2019
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    Representative immunofluorescent staining of β3-tubulin (green) of SPG4-derived neurons treated LNA-miR-33a for 48 hours. In the latest issue of Clinical Science (volume 133, issue 4), Nakazeki et al. demonstrate through studies on induced pluripotent stem cell-derived cortical neurons that miR-33a is a potential therapeutic target for the treatment of SPG4-related hereditary spastic paraplegia.
ISSN 0143-5221
EISSN 1470-8736
In this Issue

Review Articles

Histone acetylation and DNA methylation in ischemia/reperfusion injury
Jinhua Tang; Shougang Zhuang
Clin Sci (Lond) (2019) 133 (4): 597–609.
View Articletitled, Histone acetylation and DNA methylation in ischemia/reperfusion injury
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Research Articles

Matrine reduces cigarette smoke-induced airway neutrophilic inflammation by enhancing neutrophil apoptosis
Xuhua Yu; Huei Jiunn Seow; Hao Wang; Desiree Anthony; Steven Bozinovski; Lin Lin; Ji-Ming Ye; Ross Vlahos
Clin Sci (Lond) (2019) 133 (4): 551–564.
View Articletitled, Matrine reduces cigarette smoke-induced airway neutrophilic inflammation by enhancing neutrophil apoptosis
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NLRP3 activation induced by neutrophil extracellular traps sustains inflammatory response in the diabetic wound
Dan Liu; Peilang Yang; Min Gao; Tianyi Yu; Yan Shi; Meng Zhang; Min Yao; Yan Liu; Xiong Zhang
Clin Sci (Lond) (2019) 133 (4): 565–582.
View Articletitled, NLRP3 activation induced by neutrophil extracellular traps sustains inflammatory response in the diabetic wound
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MiR-33a is a therapeutic target in SPG4-related hereditary spastic paraplegia human neurons
Fumiko Nakazeki; Itaru Tsuge; Takahiro Horie; Keiko Imamura; Kayoko Tsukita; Akitsu Hotta; Osamu Baba; Yasuhide Kuwabara; Tomohiro Nishino; Tetsushi Nakao; Masataka Nishiga; Hitoo Nishi; Yasuhiro Nakashima; Yuya Ide; Satoshi Koyama; Masahiro Kimura; Shuhei Tsuji; Motoko Naitoh; Shigehiko Suzuki; Yuishin Izumi; Toshitaka Kawarai; Ryuji Kaji; Takeshi Kimura; Haruhisa Inoue; Koh Ono
Clin Sci (Lond) (2019) 133 (4): 583–595.
View Articletitled, <em>MiR-33a</em> is a therapeutic target in SPG4-related hereditary spastic paraplegia human neurons
Supplementary data
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A new mechanism of arterial calcification in diabetes: interaction between H3K18 lactylation and CHI3L1
Arterial effects of anthracycline: structural and inflammatory assessments in non-human primates and lymphoma patients
Distinct effects of obesity and diabetes on the action potential waveform and inward currents in rat ventricular myocytes
Higher circulating ACE2 and DPP3 but reduced ACE and angiotensinogen in hyperreninemic sepsis patients
RNA-binding protein HuR regulates the transition of septic AKI to CKD by modulating CD147
  • Online ISSN 1470-8736
  • Print ISSN 0143-5221

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