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Issues
April 2019
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Cover Image
Cover Image
The incidence of inflammatory bowel disease has increased dramatically over the past two decades. In the latest issue of Clinical Science (volume 133, issue 8), Zhang et al. explore the potential of clinical compound LY3009120 as an inhibitor of necroptosis - a key process in the pathogenesis of IBD. This cover shows immunohistochemically stained mouse colon tissue from the study.
ISSN 0143-5221
EISSN 1470-8736
In this Issue
Review Articles
Commentaries
Research Articles
A pan-RAF inhibitor LY3009120 inhibits necroptosis by preventing phosphorylation of RIPK1 and alleviates dextran sulfate sodium-induced colitis
Clin Sci (Lond) (2019) 133 (8): 919–932.
Epoxyeicosatrienoic acid analog EET-B attenuates post-myocardial infarction remodeling in spontaneously hypertensive rats
Jan Neckář; Md. Abdul Hye Khan; Garrett J. Gross; Michaela Cyprová; Jaroslav Hrdlička; Alena Kvasilová; John R. Falck; William B. Campbell; Lenka Sedláková; Šárka Škutová; Veronika Olejníčková; Martina Gregorovičová; David Sedmera; František Kolář; John D. Imig
Clin Sci (Lond) (2019) 133 (8): 939–951.
The human duodenal mucosa harbors all components for a local renin angiotensin system
Clin Sci (Lond) (2019) 133 (8): 971–982.
Rhinovirus-induces progression of lung disease in a mouse model of COPD via IL-33/ST2 signaling axis
Joao A. Gimenes, Jr; Vikram Srivastava; Hymavathi ReddyVari; Sudhir Kotnala; Rahul Mishra; Mohamed Farazuddin; Wuyan Li; Umadevi S. Sajjan
Clin Sci (Lond) (2019) 133 (8): 983–996.
Glutaminolysis and lipoproteins are key factors in late immune recovery in successfully treated HIV-infected patients
Isaac Rosado-Sánchez; Esther Rodríguez-Gallego; Joaquim Peraire; Consuelo Viladés; Pol Herrero; Fran Fanjul; Félix Gutiérrez; Enrique Bernal; Ricardo Pelazas; Manuel Leal; Sergi Veloso; Miguel López-Dupla; Julià Blanco; Francesc Vidal; Yolanda María Pacheco; Anna Rull
Clin Sci (Lond) (2019) 133 (8): 997–1010.
