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July 2020
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Cover Image
Cover Image
In this issue of Clinical Science (volume 134, issue 13), Qiu and Ma et al. discuss the possible pathogenic role of human C-reactive protein (hCRP) in diabetic retinopathy. They found that hCRP promotes ischemia-induced retinal neovascularization in a rat model of oxygen-induced retinopathy. This cover features an image of a flat-mounted rat retina from their study.
ISSN 0143-5221
EISSN 1470-8736
Correction: miR- 210 transferred by lung cancer cell-derived exosomes may act as proangiogenic factor in cancer-associated fibroblasts by modulating JAK2/STAT3 pathway
Clin Sci (Lond) (2020) 134 (13): 1801–1804.
Editorial
Rethinking animal models of sepsis – working towards improved clinical translation whilst integrating the 3Rs
Clin Sci (Lond) (2020) 134 (13): 1715–1734.
Review Articles
Non-alcoholic fatty liver disease: a metabolic burden promoting atherosclerosis
Clin Sci (Lond) (2020) 134 (13): 1775–1799.
Anthracycline-induced cardiomyopathy: cellular and molecular mechanisms
Clin Sci (Lond) (2020) 134 (13): 1859–1885.
Commentaries
Macrophages—the immune effector guardians of the lung: impact of corticosteroids on their functional responses
Clin Sci (Lond) (2020) 134 (13): 1631–1635.
Research Articles
Connexin 43 prevents the progression of diabetic renal tubulointerstitial fibrosis by regulating the SIRT1-HIF-1α signaling pathway
Xiaohong Sun; Kaipeng Huang; Xiao Haiming; Zeyuan Lin; Yan Yang; Meng Zhang; Peiqing Liu; Heqing Huang
Clin Sci (Lond) (2020) 134 (13): 1573–1592.
Tubular transcriptional co-activator with PDZ-binding motif protects against ischemic acute kidney injury
Chia-Lin Wu; Chia-Chu Chang; Tao-Hsiang Yang; Alexander Charng-Dar Tsai; Jui-Lin Wang; Chung-Ho Chang; Der-Cherng Tarng
Clin Sci (Lond) (2020) 134 (13): 1593–1612.
Pathogenic role of human C-reactive protein in diabetic retinopathy
Fangfang Qiu; Xiang Ma; Young-Hwa Shin; Jianglei Chen; Qian Chen; Kelu Zhou; Wenjing Wu; Wentao Liang; Yalin Wu; Qing Song; Jian-Xing Ma
Clin Sci (Lond) (2020) 134 (13): 1613–1629.
Cigarette smoking blocks the benefit from reduced weight gain for insulin action by shifting lipids deposition to muscle
Anwar Khan; Sherouk Fouda; Ali Mahzari; Stanley M.H. Chan; Xiu Zhou; Cherubina Ratnam; Ross Vlahos; Ji-Ming Ye
Clin Sci (Lond) (2020) 134 (13): 1659–1673.
Neutrophil elastase triggers the development of autoimmune diabetes by exacerbating innate immune responses in pancreatic islets of non-obese diabetic mice
Lingling Shu; Ling Zhong; Yang Xiao; Xiaoping Wu; Yang Liu; Xue Jiang; Tao Tang; RubyLaiChong Hoo; Zhiguang Zhou; Aimin Xu
Clin Sci (Lond) (2020) 134 (13): 1679–1696.
Airway epithelial integrin β4 suppresses allergic inflammation by decreasing CCL17 production
Lin Yuan; Xun Zhang; Ming Yang; Xizi Du; Leyuan Wang; Shuangyan Wu; Mengping Wu; Zhen Duan; Gelei Xiao; Yizhou Zou; Yang Xiang; Xiangping Qu; Huijun Liu; Ling Qin; Qingwu Qin; Xiaoqun Qin; Chi Liu
Clin Sci (Lond) (2020) 134 (13): 1735–1749.
Greater high-mobility group box 1 in male compared with female spontaneously hypertensive rats worsens renal ischemia–reperfusion injury
Clin Sci (Lond) (2020) 134 (13): 1751–1762.
Ctcf is required for renin expression and maintenance of the structural integrity of the kidney
Clin Sci (Lond) (2020) 134 (13): 1763–1774.
Clinically relevant high levels of human C-reactive protein induces endothelial dysfunction and hypertension by inhibiting the AMPK-eNOS axis
Lele Cheng; Liang Wang; Manyun Guo; Jinlong He; Yangyang Deng; Junhui Liu; Yuanyuan Wei; Chen Wang; Juan Zhou; Li Ma; Qing Song; Zuyi Yuan; Yue Wu
Clin Sci (Lond) (2020) 134 (13): 1805–1819.
Circular RNA circFGD4 suppresses gastric cancer progression via modulating miR-532-3p/APC/β-catenin signalling pathway
Clin Sci (Lond) (2020) 134 (13): 1821–1839.
A long noncoding RNA CHAIR protects the heart from pathological stress
Clin Sci (Lond) (2020) 134 (13): 1843–1857.
Corrections
Expression of Concern
Expression of Concern: Alamandine attenuates hepatic fibrosis by regulating autophagy induced by NOX4-dependent ROS
Clin Sci (Lond) (2020) 134 (13): 1675.
Expression of Concern: Normal-sodium diet compared with low-sodium diet in compensated congestive heart failure: is sodium an old enemy or a new friend?
Clin Sci (Lond) (2020) 134 (13): 1841.
