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June 2022
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Cover Image
Cover Image
Salt-sensitive hypertension induces an inflammation-associated increase in lymphatic vessel density in the testes of mice. The cover of this issue of Clinical Science (volume 136, issue 11) features a 3D model of confocal images from the study by Navaneethabalakrishnan et al. showing LYVE-1 positive lymphatic vessels in a CUBIC-cleared testis from a mouse with salt-sensitive hypertension.
ISSN 0143-5221
EISSN 1470-8736
In this Issue
Review Articles
Novel insights in endocrine and metabolic pathways in sepsis and gaps for future research
Clin Sci (Lond) (2022) 136 (11): 861–878.
Research Articles
Diminished Rbfox1 increases vascular constriction by dynamically regulating alternative splicing of CaV1.2 calcium channel in hypertension
Miaomiao Song; Wei Hou; Atta Ul Mustafa; Pengpeng Li; Jianzhen Lei; Yingying Zhou; Li Ji; Yu Sun; Hongmei Zhou; Yinyan Xu; Juejin Wang
Clin Sci (Lond) (2022) 136 (11): 803–817.
Persistent vascular congestion in male spontaneously hypertensive rats contributes to delayed recovery of renal function following renal ischemia perfusion compared with females
Riyaz Mohamed; Gene R. Crislip; Sarah McLarnon; Qingqing Wei; Paul M. O’Connor; Jennifer C. Sullivan
Clin Sci (Lond) (2022) 136 (11): 825–840.
Promoting mitochondrial fusion in doxorubicin-induced cardiotoxicity: a novel therapeutic target for cardioprotection
Chayodom Maneechote; Thawatchai Khuanjing; Benjamin Ongnok; Apiwan Arinno; Nanthip Prathumsap; Titikorn Chunchai; Busarin Arunsak; Wichwara Nawara; Siriporn C. Chattipakorn; Nipon Chattipakorn
Clin Sci (Lond) (2022) 136 (11): 841–860.
Hypertension induces gonadal macrophage imbalance, inflammation, lymphangiogenesis, and dysfunction
Shobana Navaneethabalakrishnan; Brooke K. Wilcox; Bethany L. Goodlett; Malea M. Murphy; Brett M. Mitchell
Clin Sci (Lond) (2022) 136 (11): 879–894.
Silencing GOLGA8B inhibits cell invasion and metastasis by suppressing STAT3 signaling pathway in lung squamous cell carcinoma
Clin Sci (Lond) (2022) 136 (11): 895–909.
Commentaries
Methylglyoxal and glyoxalase 1—a metabolic stress pathway-linking hyperglycemia to the unfolded protein response and vascular complications of diabetes
Clin Sci (Lond) (2022) 136 (11): 819–824.