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Medical Research Society Meeting 16–17th January 1981

Oral Communication

The Multi-Wire Proportional Counter for the Detection of ³H in Biological Systems

B. J. Scott; J. E. Bateman; A. R. Bradwell; M. Hawkesworth

Clin Sci (Lond) (1981) 60 (3): 1P.

View Articletitled, The Multi-Wire Proportional Counter for the Detection of 3H in Biological Systems

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Effect of Insulin and Glucose on Very-Low-Density Lipoprotein Triglyceride Secretion by Cultured Adult Rat Hepatocytes

P. N. Durrington; R. S. Newton; D. B. Weinstein; D. Steinberg

Clin Sci (Lond) (1981) 60 (3): 1P.

View Articletitled, Effect of Insulin and Glucose on Very-Low-Density Lipoprotein Triglyceride Secretion by Cultured Adult Rat Hepatocytes

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Triglyceride-Rich Lipoproteins in Chronic Renal Failure: C-apolipoprotein Composition and Interaction with Lipoprotein Lipase

P. M. Dodson; J. Stocks; G. Holdsworth; D. J. Galton

Clin Sci (Lond) (1981) 60 (3): 1P.

View Articletitled, Triglyceride-Rich Lipoproteins in Chronic Renal Failure: C-apolipoprotein Composition and Interaction with Lipoprotein Lipase

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Does the Abnormal Apoprotein Composition of High-Density Lipoprotein in Patients with Liver Disease Contribute to Their Anaemia?

J. S. Owen; D. S. Harry; D. J. C. Brown; N. McIntyre

Clin Sci (Lond) (1981) 60 (3): 2P.

View Articletitled, Does the Abnormal Apoprotein Composition of High-Density Lipoprotein in Patients with Liver Disease Contribute to Their Anaemia?

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Decreased Erythrocyte Membrane Fluidity and Altered Lipid Composition in Human Liver Disease

J. S. Owen; K. R. Bruckdorfer; R. C. Day; N. McIntyre

Clin Sci (Lond) (1981) 60 (3): 2P.

View Articletitled, Decreased Erythrocyte Membrane Fluidity and Altered Lipid Composition in Human Liver Disease

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A Method for Investigating the Effects of Drugs on the Prostaglandin Synthetase of Single Rectal Biopsies

C. J. Hawkey; D. P. Jewell

Clin Sci (Lond) (1981) 60 (3): 2P.

View Articletitled, A Method for Investigating the Effects of Drugs on the Prostaglandin Synthetase of Single Rectal Biopsies

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Characteristics in vitro and Survival in vivo of Erythrocyte ‘Ghosts’ Prepared Under Iso-Osmotic Conditions by Using High Voltage Electric Fields

R. A. Chalmers; U. Sprandel; A. R. Hubbard

Clin Sci (Lond) (1981) 60 (3): 2P–3P.

View Articletitled, Characteristics in vitro and Survival in vivo of Erythrocyte ‘Ghosts’ Prepared Under Iso-Osmotic Conditions by Using High Voltage Electric Fields

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Platelet Anti-Aggregatory and Adp-Ase Activities of Human Placental Cultures

M. A. Khoker; B. Oilier; P. Dandona; R. A. Hutton; D. Lane

Clin Sci (Lond) (1981) 60 (3): 3P.

View Articletitled, Platelet Anti-Aggregatory and Adp-Ase Activities of Human Placental Cultures

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Human Monoclonal Antibodies to Tumour Cell Surfaces

Karol Sikora

Clin Sci (Lond) (1981) 60 (3): 3P.

View Articletitled, Human Monoclonal Antibodies to Tumour Cell Surfaces

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Analytical Subcellular Fractionation with Enzymic Microassay of Human Peripheral Blood Lymphocytes

T. Shah; D. Webster; T. J. Peters

Clin Sci (Lond) (1981) 60 (3): 3P–4P.

View Articletitled, Analytical Subcellular Fractionation with Enzymic Microassay of Human Peripheral Blood Lymphocytes

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Monocyte Function in Rheumatoid Arthritis (Ra) with Vasculitis and Systemic Lupus Erythematosus (Sue): Evidence for a Defect in Immune Phagocytosis

N. Hurst; G. Nuki

Clin Sci (Lond) (1981) 60 (3): 4P.

View Articletitled, Monocyte Function in Rheumatoid Arthritis (Ra) with Vasculitis and Systemic Lupus Erythematosus (Sue): Evidence for a Defect in Immune Phagocytosis

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Characterization of the Hepatocyte Plasma Membrane Transport Mechanism for Lactate

J. P. Monson; J. A. Smith; R. D. Cohen; R. A. Iles

Clin Sci (Lond) (1981) 60 (3): 4P–5P.

View Articletitled, Characterization of the Hepatocyte Plasma Membrane Transport Mechanism for Lactate

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Measurement of Intestinal Permeability in Human Neonates

E. A. Fagan; R. Murphy; D. Bentley; V. S. Chadwick

Clin Sci (Lond) (1981) 60 (3): 5P.

View Articletitled, Measurement of Intestinal Permeability in Human Neonates

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Indium-Labelled Leucocyte Scanning in Crohn's Disease

S. H. Saverymuttu; A. P. Peters; J. P. Lavender; H. J. Hodgson; V. S. Chadwick

Clin Sci (Lond) (1981) 60 (3): 5P.

View Articletitled, Indium-Labelled Leucocyte Scanning in Crohn's Disease

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Cholesteryl Esters in Bile in Cholecystitis

E. Kouroumalis; P. E. Ross; D. Hopwood; I. A. D. Bouchier

Clin Sci (Lond) (1981) 60 (3): 5P.

View Articletitled, Cholesteryl Esters in Bile in Cholecystitis

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No Support from Complement Profiles Including in Vivo C3 Activation for Immune Complex Aetiology in the Pathogenesis of Primary Biliary Cirrhosis

A. F. MacKlon; P. Bird; G. Bird; O. James

Clin Sci (Lond) (1981) 60 (3): 5P–6P.

View Articletitled, No Support from Complement Profiles Including in Vivo C3 Activation for Immune Complex Aetiology in the Pathogenesis of Primary Biliary Cirrhosis

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Comparison of Weight Loss, Steatorrhoea and Faecal Calorie Excretion after Two Types of Intestinal Bypass in the Rat

R. C. M. McGouran; Liza Ang; J. D. Maxwell

Clin Sci (Lond) (1981) 60 (3): 6P.

View Articletitled, Comparison of Weight Loss, Steatorrhoea and Faecal Calorie Excretion after Two Types of Intestinal Bypass in the Rat

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Effect of Pancreatico-Biliary Diversion (PBD) on the Small Intestine in Orally and Parenterally-Fed Rats

B. M. Miazza; H. Levan; S. Vaja; R. H. Dowling

Clin Sci (Lond) (1981) 60 (3): 6P.

View Articletitled, Effect of Pancreatico-Biliary Diversion (PBD) on the Small Intestine in Orally and Parenterally-Fed Rats

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Is the Renin-Angiotensin-Aldosterone System Involved in Sodium Retention of the Nephrotic Syndrome?

E. A. Brown; N. D. Markandu; J. E. Roulston; B. E. Jones; G. A. MacGregor

Clin Sci (Lond) (1981) 60 (3): 6P.

View Articletitled, Is the Renin-Angiotensin-Aldosterone System Involved in Sodium Retention of the Nephrotic Syndrome?

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Circumstantial Evidence That An Abnormality of Calcium Transport May Be Important in Essential Hypertension

G. A. MacGregor; N. D. Markandu; J. Bayliss; M. Brown; J. E. Roulston

Clin Sci (Lond) (1981) 60 (3): 6P–7P.

View Articletitled, Circumstantial Evidence That An Abnormality of Calcium Transport May Be Important in Essential Hypertension

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Relationship between Arterial Blood Pressure and Dietary Sodium Intake in Essential Hypertension and in Normotensive Subjects

P. S. Parfrey; N. D. Markandu; J. E. Roulston; B. E. Jones; G. A. MacGregor

Clin Sci (Lond) (1981) 60 (3): 7P.

View Articletitled, Relationship between Arterial Blood Pressure and Dietary Sodium Intake in Essential Hypertension and in Normotensive Subjects

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Comparative Efficacy of Three Long-Acting β-Receptor-Blocking Agents against Conventional Propranolol: β-Receptor Blockade in the 24Th Hour after a Single Dose

G. R. Jones; M. A. Mir

Clin Sci (Lond) (1981) 60 (3): 7P.

View Articletitled, Comparative Efficacy of Three Long-Acting β-Receptor-Blocking Agents against Conventional Propranolol: β-Receptor Blockade in the 24Th Hour after a Single Dose

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Response of Forearm Resistance Vessels to Verapamil and Sodium Nitroprusside in Normal and Hypertensive Men: Evidence for a Functional Abnormality of Vascular Smooth Muscle in Primary Hypertension

B. F. Robinson; S. Bayley; R. J. Dobbs

Clin Sci (Lond) (1981) 60 (3): 7P–8P.

View Articletitled, Response of Forearm Resistance Vessels to Verapamil and Sodium Nitroprusside in Normal and Hypertensive Men: Evidence for a Functional Abnormality of Vascular Smooth Muscle in Primary Hypertension

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Abnormalities of Leucocyte Sodium Transport in Essential Hypertension. a Possible Role for a Circulating Factor?

L. Poston; R. B. Sewell; P. J. Richardson; R. Williams

Clin Sci (Lond) (1981) 60 (3): 8P.

View Articletitled, Abnormalities of Leucocyte Sodium Transport in Essential Hypertension. a Possible Role for a Circulating Factor?

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Circulating Dopamine and Renin Release

S. G. Ball; M. Tree

Clin Sci (Lond) (1981) 60 (3): 8P.

View Articletitled, Circulating Dopamine and Renin Release

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Circadian Variation in Blood Pressure and Heart Rate in Patients with Autonomic Neuropathy

S. Mann; D. G. Altman; E. B. Raftery; R. Bannister

Clin Sci (Lond) (1981) 60 (3): 8P–9P.

View Articletitled, Circadian Variation in Blood Pressure and Heart Rate in Patients with Autonomic Neuropathy

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Renal Prostaglandins during Excretion of An Intravenous Infusion of Sodium Chloride in Normal Human Subjects

M. L. Watson; A. T. Lambie; A. Ungar

Clin Sci (Lond) (1981) 60 (3): 9P.

View Articletitled, Renal Prostaglandins during Excretion of An Intravenous Infusion of Sodium Chloride in Normal Human Subjects

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Erythrocyte Metabolism in Patients on Haemodialysis (HD) and Continuous Ambulant Peritoneal Dialysis (Capd)

G. P. Summerfield; A. J. Bellingham; A. M. Forbes; H. J. Goldsmith; L. A. Robinson

Clin Sci (Lond) (1981) 60 (3): 9P.

View Articletitled, Erythrocyte Metabolism in Patients on Haemodialysis (HD) and Continuous Ambulant Peritoneal Dialysis (Capd)

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Studies on Urine Free Dopamine Output in Rats with Acute Renal Failure

I. F. Casson; M. R. Lee

Clin Sci (Lond) (1981) 60 (3): 9P.

View Articletitled, Studies on Urine Free Dopamine Output in Rats with Acute Renal Failure

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Differential Prostacyclin Production by Tissues from Pregnant Diabetic Rats

K. E. H. El Tahir; K. I. Williams; D. J. Betteridge; J. P. D. Reckless

Clin Sci (Lond) (1981) 60 (3): 9P–10P.

View Articletitled, Differential Prostacyclin Production by Tissues from Pregnant Diabetic Rats

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Serum Long Acting Thyroid Stimulator (Lats) and Lats-Protector (LATS-P) in Graves' Disease Complicated by Localized Myxoedema

C. A. Hardisty; D. S. Munro

Clin Sci (Lond) (1981) 60 (3): 10P.

View Articletitled, Serum Long Acting Thyroid Stimulator (Lats) and Lats-Protector (LATS-P) in Graves' Disease Complicated by Localized Myxoedema

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Similarity of Human Thyroid Adenylate Cyclase Response to Thyrotrophin (Tsh) and Thyroid Stimulating Immunoglobulins (Tsig)

C. A. Ollis; S. MacNeil; A. Crawford; L. Chivers; H. Humphries; D. S. Munro; S. Tomlinson

Clin Sci (Lond) (1981) 60 (3): 10P.

View Articletitled, Similarity of Human Thyroid Adenylate Cyclase Response to Thyrotrophin (Tsh) and Thyroid Stimulating Immunoglobulins (Tsig)

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Estimates of Calcitonin Secretion Rates in Health, Paget's Disease and Renal Failure

J. A. Kanis; G. Heynen; T. Cundy; S. Gaspar

Clin Sci (Lond) (1981) 60 (3): 10P–11P.

View Articletitled, Estimates of Calcitonin Secretion Rates in Health, Paget's Disease and Renal Failure

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The Diagnostic and Aetiological Significance of Certain Ultrastructural Features of the Osteoclasts in Paget's Disease of Bone

L. Harvey; T. Gray; M. N. C. Beneton-Beresford; D. L. Douglas; D. J. Beard; J. A. Kanis; R. G. G. Russell

Clin Sci (Lond) (1981) 60 (3): 11P.

View Articletitled, The Diagnostic and Aetiological Significance of Certain Ultrastructural Features of the Osteoclasts in Paget's Disease of Bone

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Biologically Active Parathyroid Hormone in Foetal and Maternal Plasma

J. Allgrove; R. M. Manning; S. Adami; J. Chayen; J. L. H. O'Riordan

Clin Sci (Lond) (1981) 60 (3): 11P.

View Articletitled, Biologically Active Parathyroid Hormone in Foetal and Maternal Plasma

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Autonomy of Parathyroids in Secondary Hyperparathyroidism

S. Adami; R. M. Manning; J. Allgrove; J. H. Gleed; N. Muirhead; G. R. D. Catto; J. L. H. O'Riordan

Clin Sci (Lond) (1981) 60 (3): 11P–12P.

View Articletitled, Autonomy of Parathyroids in Secondary Hyperparathyroidism

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Intracellular Degradation of Prolactin by Rat and Human Anterior Pituitary: Direct Evidence for Involvement of Lysosomes

L. De Marco; K. Mashiter; T. J. Peters

Clin Sci (Lond) (1981) 60 (3): 12P.

View Articletitled, Intracellular Degradation of Prolactin by Rat and Human Anterior Pituitary: Direct Evidence for Involvement of Lysosomes

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Immunoglobulins Blocking the Trophic Action of Tsh in Primary Myxoedema

H. A. Drexhage; G. F. Bottazzo; L. Bitensky; J. Chayen; D. Doniach

Clin Sci (Lond) (1981) 60 (3): 12P.

View Articletitled, Immunoglobulins Blocking the Trophic Action of Tsh in Primary Myxoedema

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Stimulation of Prolactin by Parathyroid Hormone

P. Dandona; S. N. Hanna; M. Gore; C. W. H. Havard

Clin Sci (Lond) (1981) 60 (3): 13P.

View Articletitled, Stimulation of Prolactin by Parathyroid Hormone

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A New Exercise Test in Coronary Heart Disease

M. S. Elamin; D. A. S. G. Mary; D. R. Smith; R. J. Linden

Clin Sci (Lond) (1981) 60 (3): 13P.

View Articletitled, A New Exercise Test in Coronary Heart Disease

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Transient Changes in Left Ventricular Volume in Acute Myocardial Ischaemia

G. J. Davies; S. Chierchia; M. Myers; A. Maseri; R. E. Steiner

Clin Sci (Lond) (1981) 60 (3): 13P.

View Articletitled, Transient Changes in Left Ventricular Volume in Acute Myocardial Ischaemia

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Actions of Ouabain and of Diuretics on Na⁺-K⁺ Exchanges in Skeletal and Heart Muscle

S. S. Bhattacharya; A. Jackson; C. T. G. Flear

Clin Sci (Lond) (1981) 60 (3): 13P–14P.

View Articletitled, Actions of Ouabain and of Diuretics on Na+-K+ Exchanges in Skeletal and Heart Muscle

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Actions of Diuretics on Sodium-Potassium Exchanges in Skeletal and Heart Muscle, in the Presence of Ouabain

S. S. Bhattacharya; A. Jackson; C. T. G. Flear

Clin Sci (Lond) (1981) 60 (3): 14P.

View Articletitled, Actions of Diuretics on Sodium-Potassium Exchanges in Skeletal and Heart Muscle, in the Presence of Ouabain

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Effects of Platelet Inhibition on Myocardial Ischaemia

K. M. Fox; Anne Jonathan; E. Chung; A. P. Selwyn

Clin Sci (Lond) (1981) 60 (3): 14P.

View Articletitled, Effects of Platelet Inhibition on Myocardial Ischaemia

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Non/Invasive Detection of Myocardial Ischaemia Produced by Provocative Tests. Studies Using 82 Rubidium and Positron Tomography

R. M. Allan; P. Horlock; J. C. Clark; A. Maseri; A. Selwyn

Clin Sci (Lond) (1981) 60 (3): 14P–15P.

View Articletitled, Non/Invasive Detection of Myocardial Ischaemia Produced by Provocative Tests. Studies Using 82 Rubidium and Positron Tomography

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The Ability of the ¹⁵O₂ Inhalation Technique to Measure Regional Cerebral Blood Flow and Metabolism: Experimental Assessment in Dogs by Using CO₂ Reactivity

C. G. Rhodes; G. L. Lenzi; R. S. J. Frackowiak; T. Jones; C. Pozzilli

Clin Sci (Lond) (1981) 60 (3): 15P.

View Articletitled, The Ability of the 15O2 Inhalation Technique to Measure Regional Cerebral Blood Flow and Metabolism: Experimental Assessment in Dogs by Using CO2 Reactivity

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Regional Cerebral Blood Flow and Oxygen Consumption in Acute Hemispheric Stroke Measured with ¹⁵O₂ and Positron Emission Tomography

R. S. J. Frackowiak; T. Jones; G. L. Lenzi

Clin Sci (Lond) (1981) 60 (3): 15P.

View Articletitled, Regional Cerebral Blood Flow and Oxygen Consumption in Acute Hemispheric Stroke Measured with 15O2 and Positron Emission Tomography

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Quantitative Measurement of Regional Extravascular Lung Density with Positron Emission and Transmission Tomography

C. G. Rhodes; P. Wollmer; F. Fazio; T. Jones

Clin Sci (Lond) (1981) 60 (3): 15P–16P.

View Articletitled, Quantitative Measurement of Regional Extravascular Lung Density with Positron Emission and Transmission Tomography

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Electromyographic Activity of the Laryngeal Muscles during Breathing in Normal Subjects and Patients with Lung Disease

Julia Payne; T. Higenbottam

Clin Sci (Lond) (1981) 60 (3): 16P.

View Articletitled, Electromyographic Activity of the Laryngeal Muscles during Breathing in Normal Subjects and Patients with Lung Disease

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Acetazolamide in the Control of Acute Mountain Sickness

A. R. Bradwell; P. Forster; B. Coles; J. D. Delamare; The Birmingham Medical Research Expeditionary society

Clin Sci (Lond) (1981) 60 (3): 16P.

View Articletitled, Acetazolamide in the Control of Acute Mountain Sickness

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Hydrogen Peroxide Release by Human Alveolar MacRophages

A. P. Greening; D. B. Lowrie

Clin Sci (Lond) (1981) 60 (3): 16P.

View Articletitled, Hydrogen Peroxide Release by Human Alveolar MacRophages

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Free Secretory Piece in Bronchitis and Its Relationship to other Components of the Pulmonary Secretory Iga System

R. A. Stockley; S. C. Afford; D. Burnett

Clin Sci (Lond) (1981) 60 (3): 16P–17P.

View Articletitled, Free Secretory Piece in Bronchitis and Its Relationship to other Components of the Pulmonary Secretory Iga System

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Electrical Impedance Technique for Measuring Intrathoracic Events

C. Bryant; G. Cumming; A. Turner

Clin Sci (Lond) (1981) 60 (3): 17P.

View Articletitled, Electrical Impedance Technique for Measuring Intrathoracic Events

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Effect of Propranolol on the Airway Response to Pge₂ in Man

R. A. Lewis; R. V. Seth; A. E. Tattersfield

Clin Sci (Lond) (1981) 60 (3): 17P.

View Articletitled, Effect of Propranolol on the Airway Response to Pge2 in Man

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Breathlessness and the Ventilatory Drives of Exercise, Hypercapnoea and Hypoxia

A. Guz; L. Adams; K. Minty; K. Murphy

Clin Sci (Lond) (1981) 60 (3): 17P–18P.

View Articletitled, Breathlessness and the Ventilatory Drives of Exercise, Hypercapnoea and Hypoxia

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Endogenous Circulating Catecholamines and Histamine in Asthmatic Subjects

P. J. Barnes; M. Brown; P. Ind; C T Dollery

Clin Sci (Lond) (1981) 60 (3): 18P.

View Articletitled, Endogenous Circulating Catecholamines and Histamine in Asthmatic Subjects

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Effect of Carbon Monoxide on the Oxygen Dissociation Curve and Oxygen Transport in Patients with Chronic Bronchitis

N. S. Zhong; A. C. Morgan; J. Walker; D. C. Flenley

Clin Sci (Lond) (1981) 60 (3): 18P–19P.

View Articletitled, Effect of Carbon Monoxide on the Oxygen Dissociation Curve and Oxygen Transport in Patients with Chronic Bronchitis

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Poster Communication

Ultrasound Imaging in the Diagnosis of Muscle Disease

J. Z. Heckmatt; V. Dubowitz; S. Leeman

Clin Sci (Lond) (1981) 60 (3): 19P.

View Articletitled, Ultrasound Imaging in the Diagnosis of Muscle Disease

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Enzymic Analysis of Human Skeletal Muscle Biopsy Samples

F. Martin; J. Levi; G. Slavin; T. J. Peters

Clin Sci (Lond) (1981) 60 (3): 19P.

View Articletitled, Enzymic Analysis of Human Skeletal Muscle Biopsy Samples

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Cerebral Blood Flow and Oxygen and Glucose Utilization in the Neonatal Piglet

P. A. Flecknell; R. Wootton; Muriel John

Clin Sci (Lond) (1981) 60 (3): 19P.

View Articletitled, Cerebral Blood Flow and Oxygen and Glucose Utilization in the Neonatal Piglet

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Alanine Disappearance Rate during Prolonged Starvation in Obese Subjects

R. Swaminathan; D. B. Morgan; J. K. Wales

Clin Sci (Lond) (1981) 60 (3): 19P–20P.

View Articletitled, Alanine Disappearance Rate during Prolonged Starvation in Obese Subjects

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Low Density Lipoprotein Binding by Cultured Human Skin Fibroblasts; the Inhibitory Effect of High-Density Lipoprotein from Patients with Liver Disease

J. S. Owen; P. Mistry; H. Goodall; P. Chu; D. S. Harry; R. C. Day; N. McIntyre

Clin Sci (Lond) (1981) 60 (3): 20P.

View Articletitled, Low Density Lipoprotein Binding by Cultured Human Skin Fibroblasts; the Inhibitory Effect of High-Density Lipoprotein from Patients with Liver Disease

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Regulation of Granulocyte and MacRophage Production by Activated Lymphocytes

M. Y. Gordon; E. C. Gordon-Smith

Clin Sci (Lond) (1981) 60 (3): 20P.

View Articletitled, Regulation of Granulocyte and MacRophage Production by Activated Lymphocytes

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Human Neutrophil Pyridoxal Phosphate Phosphatase and Its Relationship to Alkaline Phosphatase

G. P. Smith; T. J. Peters

Clin Sci (Lond) (1981) 60 (3): 20P.

View Articletitled, Human Neutrophil Pyridoxal Phosphate Phosphatase and Its Relationship to Alkaline Phosphatase

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Reticuloendothelial Function in Bone Marrow Transplant Patients

J. M. Hows; E. C. Gordon-Smith

Clin Sci (Lond) (1981) 60 (3): 20P–21P.

View Articletitled, Reticuloendothelial Function in Bone Marrow Transplant Patients

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Recurrent Oral Aphthae and Associated Disorders: Results of Unselected Patients

J. R. M. Bateman; I. M. Chesner; A. J. C. Potts; J. W. Frame; P. Asquith

Clin Sci (Lond) (1981) 60 (3): 21P.

View Articletitled, Recurrent Oral Aphthae and Associated Disorders: Results of Unselected Patients

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Clinical and Electrophysiological Findings in Patients with Malignant Lymphoma Undergoing Therapy with Vinblastine or Vincristine

P. J. White; J. A. Jarratt; B. W. Hancock

Clin Sci (Lond) (1981) 60 (3): 21P.

View Articletitled, Clinical and Electrophysiological Findings in Patients with Malignant Lymphoma Undergoing Therapy with Vinblastine or Vincristine

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Aldehyde Dehydrogenase: A New Method of Assay and Kinetic Characteristics in Normal Human Liver Tissue

K. R. Palmer; M. Socolovsky; W. J. Jenkins

Clin Sci (Lond) (1981) 60 (3): 21P–22P.

View Articletitled, Aldehyde Dehydrogenase: A New Method of Assay and Kinetic Characteristics in Normal Human Liver Tissue

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An Explanation for Bile-Acid Mediated Gastritis and the Relief of Dyspepsia with Chenodeoxycholic (CDCA) and Ursodeoxycholic (UDCA) Acid Therapy

I. J. Meredith; A. Hilson; G. M. Murphy; R. H. Dowling

Clin Sci (Lond) (1981) 60 (3): 22P.

View Articletitled, An Explanation for Bile-Acid Mediated Gastritis and the Relief of Dyspepsia with Chenodeoxycholic (CDCA) and Ursodeoxycholic (UDCA) Acid Therapy

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Lysozyme in Liver Disease, a Biochemical and Histological Study

I. H. Manifold; F. M. Bishop; P. Cloke; J. C. E. Underwood; D. R. Triger

Clin Sci (Lond) (1981) 60 (3): 22P.

View Articletitled, Lysozyme in Liver Disease, a Biochemical and Histological Study

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Lipolytic Enzymes of Gall-Bladder Mucosa in Cholecystitis

E. Kouroumalis; P. E. Ross; D. Hopwood; I. A. D. Bouchier

Clin Sci (Lond) (1981) 60 (3): 22P.

View Articletitled, Lipolytic Enzymes of Gall-Bladder Mucosa in Cholecystitis

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Fractionation of Fulminant Hepatic Failure Serum to Further Characterize the Leucocyte Sodium Transport Inhibitor

R. D. Hughes; R. B. Sewell; L. Poston; R. Williams

Clin Sci (Lond) (1981) 60 (3): 23P.

View Articletitled, Fractionation of Fulminant Hepatic Failure Serum to Further Characterize the Leucocyte Sodium Transport Inhibitor

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Meal-Induced Absorption of Newly Formed Secondary Bile Acids in Normal Man

K. D. R. Setchell; A. M. Lawson; E. J. Blackstock; G. M. Murphy

Clin Sci (Lond) (1981) 60 (3): 23P.

View Articletitled, Meal-Induced Absorption of Newly Formed Secondary Bile Acids in Normal Man

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Hla-B8 and Cellular Immune Response to Gluten

F. G. Simpson; A. W. Bullen; D. A. F. Robertson; M. S. Losowsky

Clin Sci (Lond) (1981) 60 (3): 23P.

View Articletitled, Hla-B8 and Cellular Immune Response to Gluten

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Enteropancreatic Trophic Axis: A New Model for Stimulating Adaptive Pancreatic Hyperplasia

H. Levan; B. M. Miazza; S. Vaja; R. H. Dowling

Clin Sci (Lond) (1981) 60 (3): 23P–24P.

View Articletitled, Enteropancreatic Trophic Axis: A New Model for Stimulating Adaptive Pancreatic Hyperplasia

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A Comparison of the Direct and Slow Pressor Effects of Angiotensin Ii in the Conscious Rat

A. J. Brown; J. Casals-Stenzel; A. F. Lever

Clin Sci (Lond) (1981) 60 (3): 24P.

View Articletitled, A Comparison of the Direct and Slow Pressor Effects of Angiotensin Ii in the Conscious Rat

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Intra-Arterial Blood Pressure and Cardiovascular Responses in Black and White Hypertensive Subjects

D. B. Rowlands; R. D. S. Watson; T. J. Stallard; J. De Giovanni; W. A. Littler

Clin Sci (Lond) (1981) 60 (3): 24P.

View Articletitled, Intra-Arterial Blood Pressure and Cardiovascular Responses in Black and White Hypertensive Subjects

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Acute and Long-Term Actions of Prazosin in the Rabbit: Experimental Observations of the First Dose Effect

C. A. Hamilton; J. L. Reid

Clin Sci (Lond) (1981) 60 (3): 24P–25P.

View Articletitled, Acute and Long-Term Actions of Prazosin in the Rabbit: Experimental Observations of the First Dose Effect

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Plasma Catecholamine Concentrations in Mother and Infant at Birth

G. C. Inglis; M. J. Whittle; A. I. Wilson; S. G. Ball

Clin Sci (Lond) (1981) 60 (3): 25P.

View Articletitled, Plasma Catecholamine Concentrations in Mother and Infant at Birth

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Hyporeninaemic Hypoaldosteronism: A Disorder of Renal Tubular Chloride Reabsorption

P. L. Padfield; R. J. Grekin; M. G. Nicholls

Clin Sci (Lond) (1981) 60 (3): 25P.

View Articletitled, Hyporeninaemic Hypoaldosteronism: A Disorder of Renal Tubular Chloride Reabsorption

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Clinical Trial of Different Doses of ¹³¹I in Treatment of Thyrotoxicosis: 10 Year Follow-Up

C. A. Hardisty; R. N. Smith; A. J. Bethell; D. S. Munro

Clin Sci (Lond) (1981) 60 (3): 25P.

View Articletitled, Clinical Trial of Different Doses of 131I in Treatment of Thyrotoxicosis: 10 Year Follow-Up

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Effect of Corticosteroid Therapy on Plasma 1,25-Dihydroxy Vitamin D Levels

R. G. Crilly; M. Peacock; G. A. Taylor; B. F. C. Nordin

Clin Sci (Lond) (1981) 60 (3): 26P.

View Articletitled, Effect of Corticosteroid Therapy on Plasma 1,25-Dihydroxy Vitamin D Levels

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The Menopause and Fractures of the Proximal Femur

M. R. Baker

Clin Sci (Lond) (1981) 60 (3): 26P.

View Articletitled, The Menopause and Fractures of the Proximal Femur

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Dose Variation in the Treatment of Osteoporosis with Synthetic Human Parathyroid Hormone Fragment hPTH 1–34

Marisol Tellez; Joan M. Zanelli; R. Wootton; P. J. Meunier; J. A. Parsons; J. Reeve

Clin Sci (Lond) (1981) 60 (3): 26P.

View Articletitled, Dose Variation in the Treatment of Osteoporosis with Synthetic Human Parathyroid Hormone Fragment hPTH 1–34

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Ultraviolet Radiation and Vitamin D Synthesis in man

D. J. Sumner; J. Reid

Clin Sci (Lond) (1981) 60 (3): 26P–27P.

View Articletitled, Ultraviolet Radiation and Vitamin D Synthesis in man

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Interactions between Msh and α-Adrenergic Receptors on Anolis Skin

R. J. Carter; S. Shuster

Clin Sci (Lond) (1981) 60 (3): 27P.

View Articletitled, Interactions between Msh and α-Adrenergic Receptors on Anolis Skin

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Thyrocalcitonin in Osteoporotic Patients with Hypercalciuria

W. H. Taylor

Clin Sci (Lond) (1981) 60 (3): 27P.

View Articletitled, Thyrocalcitonin in Osteoporotic Patients with Hypercalciuria

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Alterations in Thyroid Hormone Levels and Left Ventricular Contractility in Primary Hypothyroidism as a Consequence of Warming

B. Northover; B. P. O'Malley; F. D. Rosenthal

Clin Sci (Lond) (1981) 60 (3): 27P.

View Articletitled, Alterations in Thyroid Hormone Levels and Left Ventricular Contractility in Primary Hypothyroidism as a Consequence of Warming

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The Intracellular Concentration of Non-Volatile Metabolic Acids in Rat Heart and Skeletal Muscle in Prolonged Hypoxia

T. I. Musch; N. T. Bateman; J. A. Dempsey

Clin Sci (Lond) (1981) 60 (3): 28P.

View Articletitled, The Intracellular Concentration of Non-Volatile Metabolic Acids in Rat Heart and Skeletal Muscle in Prolonged Hypoxia

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An Experimental Approach to Leukaemic Cardiomyopathy: Effects of Leukaemic Blast Cell Extract on Ultrastructural Changes and Mitochondrial Respiration of Rat Heart

M. A. Mir; B. M. Charalambous; N. Nicholas

Clin Sci (Lond) (1981) 60 (3): 28P.

View Articletitled, An Experimental Approach to Leukaemic Cardiomyopathy: Effects of Leukaemic Blast Cell Extract on Ultrastructural Changes and Mitochondrial Respiration of Rat Heart

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Oral Cimetidine in Man Antagonizes Cardiovascular Histamine H₂-Receptors But Does Not Affect Normal Cardiovascular Function

M. J. Boyce; K. Wareham; V. Bala Subramanian

Clin Sci (Lond) (1981) 60 (3): 28P.

View Articletitled, Oral Cimetidine in Man Antagonizes Cardiovascular Histamine H2-Receptors But Does Not Affect Normal Cardiovascular Function

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Heart Rate and Myocardial Action Potential Duration

M. J. Lab; M. I. M. Noble; D. Papadoyannis; J. W. Pidgeon; W. A. Seed

Clin Sci (Lond) (1981) 60 (3): 28P–29P.

View Articletitled, Heart Rate and Myocardial Action Potential Duration

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Relationship between Intracellular Ph and Papillary Muscle Function in vitro during Hypoxia and Hypercapnia

D. A. Woolf; C. D. Shee; I. R. Cameron

Clin Sci (Lond) (1981) 60 (3): 29P.

View Articletitled, Relationship between Intracellular Ph and Papillary Muscle Function in vitro during Hypoxia and Hypercapnia

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Is 21 Lead Superior to Bipolar Lead Monitoring during Exercise Testing in Patients with Severe Chronic Stable Angina?

M. Bowles; A. B. Davies; V. Balasubramanian; E. B. Raftery

Clin Sci (Lond) (1981) 60 (3): 29P.

View Articletitled, Is 21 Lead Superior to Bipolar Lead Monitoring during Exercise Testing in Patients with Severe Chronic Stable Angina?

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Erythrocyte Na⁺,K⁺-Dependent Adenosine Triphosphatase Activity During Digoxin Therapy

R. Swaminathan; K. Zariean; M. Cumberbatch; D. B. Morgan

Clin Sci (Lond) (1981) 60 (3): 29P.

View Articletitled, Erythrocyte Na+,K+-Dependent Adenosine Triphosphatase Activity During Digoxin Therapy

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Determinants of St Segment Change in Chronic Stable Angina

A. B. Davies; P. M. M. Cashman; V. Balasubramanian; E. B. Raftery

Clin Sci (Lond) (1981) 60 (3): 29P–30P.

View Articletitled, Determinants of St Segment Change in Chronic Stable Angina

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Relation of Isovolumic Relaxation time to Left Ventricular End-Diastolic Pressure

P. J. Oldershaw; M. Mattheos; E. Shapiro; D. G. Gibson

Clin Sci (Lond) (1981) 60 (3): 30P.

View Articletitled, Relation of Isovolumic Relaxation time to Left Ventricular End-Diastolic Pressure

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Ventricular Contraction Influences Rate of Release of Creatine Kinase in Reper-Fused Ischaemic Rat Hearts

T. V. Arnim; A. Maseri

Clin Sci (Lond) (1981) 60 (3): 30P.

View Articletitled, Ventricular Contraction Influences Rate of Release of Creatine Kinase in Reper-Fused Ischaemic Rat Hearts

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Transient Hypoxaemia during Sleep in Patients with Right-to-Left Intracardiac Shunts

J. R. Catterall; N. J. Douglas; P. M. A. Calverley; H. M. Brash; C. M. Shapiro; D. C. Flenley

Clin Sci (Lond) (1981) 60 (3): 30P.

View Articletitled, Transient Hypoxaemia during Sleep in Patients with Right-to-Left Intracardiac Shunts

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Effects of Monocytes on Lymphocyte Function in Sarcoidosis

N. McI. Johnson; J. Brostoff; B. N. Hudspith; J. R. Boot; M. W. McNicol

Clin Sci (Lond) (1981) 60 (3): 30P–31P.

View Articletitled, Effects of Monocytes on Lymphocyte Function in Sarcoidosis

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Relationship between Intracellular Ph and Muscle Fatigue in vitro

C. D. Shee; I. R. Cameron

Clin Sci (Lond) (1981) 60 (3): 31P.

View Articletitled, Relationship between Intracellular Ph and Muscle Fatigue in vitro

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The Way People Smoke: Is it Important?

L. Adams; C. Lee; R. Rawbone; A. Guz

Clin Sci (Lond) (1981) 60 (3): 31P.

View Articletitled, The Way People Smoke: Is it Important?

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Dose-Reponse Curves in vivo in the Investigation of Agonist-Antagonist Reactions in the Tracheobronchial Tree

K. F. Chung; S. J. Keyes; P. D. Snashall

Clin Sci (Lond) (1981) 60 (3): 31P.

View Articletitled, Dose-Reponse Curves in vivo in the Investigation of Agonist-Antagonist Reactions in the Tracheobronchial Tree

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Should Blood Oxygen Content Be Determined by Direct Measurement?

R. A. Banks; N. T. Cooke; P. M. I. Sutton

Clin Sci (Lond) (1981) 60 (3): 31P–32P.

View Articletitled, Should Blood Oxygen Content Be Determined by Direct Measurement?

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Effect of Hypoxia and Hypercapnia on Left and Right Ventricular Weights and on Pulmonary Vascular Histology in the Rat

A. J. Suggett; P. J. Oldershaw; N. T. Bateman

Clin Sci (Lond) (1981) 60 (3): 32P.

View Articletitled, Effect of Hypoxia and Hypercapnia on Left and Right Ventricular Weights and on Pulmonary Vascular Histology in the Rat

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Partitioning of Diffusing Capacity (D_LCO) in Lung Haemorrhage

H. C. Middleton; J. M. B. Hughes

Clin Sci (Lond) (1981) 60 (3): 32P.

View Articletitled, Partitioning of Diffusing Capacity (DLCO) in Lung Haemorrhage

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Blood Pressure and Smoking Habits in West Indians in Jamaica and in Birmingham in Comparison with Whites and Asians

J. K. Cruickshank; D. G. Beevers; L. T. Bannan; S. H. D. Jackson; M. Smith; S. Dianzumba; C. Denbow

Clin Sci (Lond) (1981) 60 (3): 32P.

View Articletitled, Blood Pressure and Smoking Habits in West Indians in Jamaica and in Birmingham in Comparison with Whites and Asians

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Editorial Review

The Importance of Clinical Pharmacology in Drug Development

C. F. George

Clin Sci (Lond) (1981) 60 (3): 247–250.

View Articletitled, The Importance of Clinical Pharmacology in Drug Development

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Articles

Radioimmunoassay of Human Cardiac Tropomyosin in Acute Myocardial Infarction

P. Cummins; B. McGurk; W. A. Littler

Clin Sci (Lond) (1981) 60 (3): 251–259.

Abstract

View Articletitled, Radioimmunoassay of Human Cardiac Tropomyosin in Acute Myocardial Infarction

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Different Distributions of Kinetically Apparent Molecular Varieties of α₂-Macroglobulin in Health and in Patients with Cryptogenic Fibrosing Alveolitis

R. M. Topping; A. H. Craven; Susan Whiting; B. G. Rigden; M. Turner-Warwick; C. W. G. Turton

Clin Sci (Lond) (1981) 60 (3): 261–265.

Abstract

View Articletitled, Different Distributions of Kinetically Apparent Molecular Varieties of α2-Macroglobulin in Health and in Patients with Cryptogenic Fibrosing Alveolitis

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Aggravation of Hypertension in Spontaneously Hypertensive Rats by Heymann Nephritis

I. Tikkanen; A. Miettinen; F. Fyhrquist; T. Törnroth

Clin Sci (Lond) (1981) 60 (3): 267–272.

Abstract

View Articletitled, Aggravation of Hypertension in Spontaneously Hypertensive Rats by Heymann Nephritis

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Renal Phosphate Adaptation in Uraemic Dogs with a Remnant Kidney

S.-F. Wen; R. W. Stoll

Clin Sci (Lond) (1981) 60 (3): 273–282.

Abstract

View Articletitled, Renal Phosphate Adaptation in Uraemic Dogs with a Remnant Kidney

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Blood-Volume Expansion in the Rat: Natriuresis Accompanied by a Fall in Filtration Fraction

D. Querido; L. C. Isaacson

Clin Sci (Lond) (1981) 60 (3): 283–293.

Abstract

View Articletitled, Blood-Volume Expansion in the Rat: Natriuresis Accompanied by a Fall in Filtration Fraction

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Lipid Peroxidation in Iron-Overloaded Spleens

A. D. Heys; T. L. Dormandy

Clin Sci (Lond) (1981) 60 (3): 295–301.

Abstract

View Articletitled, Lipid Peroxidation in Iron-Overloaded Spleens

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Evidence of Altered Copper Metabolism in Patients with Chronic Pancreatitis

Joan M. Braganza; H. J. Klass; M. Bell; G. Sturniolo

Clin Sci (Lond) (1981) 60 (3): 303–310.

Abstract

View Articletitled, Evidence of Altered Copper Metabolism in Patients with Chronic Pancreatitis

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Total Body Potassium in Relation to Thyroid Hormones and Hyperthyroidism

C. J. Edmonds; T. Smith

Clin Sci (Lond) (1981) 60 (3): 311–318.

Abstract

View Articletitled, Total Body Potassium in Relation to Thyroid Hormones and Hyperthyroidism

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Protein Degradation in Human Skeletal Muscle Tissue: The Effect of Insulin, Leucine, Amino Acids and Ions

K. Lundholm; S. Edström; L. Ekman; I. Karlberg; P. Walker; T. Scherstén

Clin Sci (Lond) (1981) 60 (3): 319–326.

Abstract

View Articletitled, Protein Degradation in Human Skeletal Muscle Tissue: The Effect of Insulin, Leucine, Amino Acids and Ions

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Short Communication

Portal Vein Prostacyclin Activity in Experimental Portal Hypertension in Rats

G. Hamilton; I. Rosza; R. Hutton; F. P. R. Chow; P. Dandona; K. E. F. Hobbs

Clin Sci (Lond) (1981) 60 (3): 327–329.

Abstract

View Articletitled, Portal Vein Prostacyclin Activity in Experimental Portal Hypertension in Rats

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Identification of N-Monoacetylcystine in Uraemic Plasma

F. Gejyo; G. Ito; Y. Kinoshita

Clin Sci (Lond) (1981) 60 (3): 331–334.

Abstract

View Articletitled, Identification of N-Monoacetylcystine in Uraemic Plasma

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Total Body-Glucose Turnover in Normal and Intra-Uterine Growth-Retarded Neonatal Piglets

P. A. Flecknell; R. Wootton; Muriel John

Clin Sci (Lond) (1981) 60 (3): 335–338.

Abstract

View Articletitled, Total Body-Glucose Turnover in Normal and Intra-Uterine Growth-Retarded Neonatal Piglets

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Human Parathyroid Gland Adenylate Cyclase Activity: Inhibition by 24,25-Dihydroxycholecalciferol in vitro

J. F. Cloix; A. Ulmann; J. D. Monet; J. L. Funck-Brentano

Clin Sci (Lond) (1981) 60 (3): 339–341.

Abstract

View Articletitled, Human Parathyroid Gland Adenylate Cyclase Activity: Inhibition by 24,25-Dihydroxycholecalciferol in vitro

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Issues

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Medical Research Society Meeting 16–17th January 1981

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