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February 1984
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ISSN 0143-5221
EISSN 1470-8736
Medical Research Society Meeting 5th and 6th January 1984
Communication
Effect of Flow Rate on Arrhythmias and Cellular Electrophysiology during Myocardial Reperfusion
Clin Sci (Lond) (1984) 66 (2): 2P.
Potential Use of Meoflazine as a Cardioprotective Agent: A Specific Blocker of the Ischaemic CA Channel?
Clin Sci (Lond) (1984) 66 (2): 2P–3P.
Age Related Changes in the Relationship between Action Potential and Stimulus Interval
Clin Sci (Lond) (1984) 66 (2): 3P.
Decelerating Inspiratory Flow Waveform Improves I Issue Dxygen Delivery in Patients on Intermittent Positive-Pressure Ventilation (IPPV)
Clin Sci (Lond) (1984) 66 (2): 5P–6P.
Characterisation of Elastase Activity in Bronchoalveolar Lavage from Smokers and Non-Smokers
Clin Sci (Lond) (1984) 66 (2): 6P–7P.
Ventilatory and Subjective Effects of Supplemental O2 during Exercise in Coad Patients
Clin Sci (Lond) (1984) 66 (2): 7P.
Inhibitory Effects of Bile Acids, Phenolic Acids and Endotoxin on Rat Brain Na+,K+-Atpase in Vitro
Clin Sci (Lond) (1984) 66 (2): 9P–10P.
Dynamics of Gallbladder Function and of the Enterohepatic Circulation Studied by Labelled Bile Acid
Clin Sci (Lond) (1984) 66 (2): 10P.
Abnormality in Bile Canalicular Membrane May Predispose to Cholesterol Gallstone Formation
Clin Sci (Lond) (1984) 66 (2): 11P.
Therapeutic Manipulation of the Entero-Hepatic Circulation in Cholesterol Cholelithiasis
Clin Sci (Lond) (1984) 66 (2): 11P.
Critical Evalulation of the Source of Haemorrhage in Massively Bleeding Gastric Ulcers
Clin Sci (Lond) (1984) 66 (2): 11P–12P.
Are Large Diameter Endoscopic Electrodes More Effective in Controlling Gastrointestinal Bleeding?
Clin Sci (Lond) (1984) 66 (2): 12P.
The Identification of Enterokinase Activity in Endocytotic Vesicles after Its Clearance by Hepatocytes
Clin Sci (Lond) (1984) 66 (2): 13P.
A Biological Role for the Activation Peptides of Trypsinogen's?
A. J. Cook; B. M. Austen; D. A. W. Grant; S. G. Cliffe; M. A. Hutton; D. L. Wingate; J. Hermon-Taylor
Clin Sci (Lond) (1984) 66 (2): 13P.
The Effect of Intravenous γGlutamyl L-Dopa on Renal Function in Normal Volunteers
Clin Sci (Lond) (1984) 66 (2): 13P–14P.
The Long Term Effect of Carotid Endarterectomy on Blood Pressure and the Carotid Sinus Baroreceptor Control of Pulse Interval
Clin Sci (Lond) (1984) 66 (2): 15P.
The Effects of Dexamethasone on Regional Cerebral Blood Flow and Oxygen Metabolism in Brain Tumour Patients
Clin Sci (Lond) (1984) 66 (2): 17P.
Neuropeptide Y (NPY) Concentrations Are Elevated in the Substantia Innominata in Alzheimers Type Dementia
Clin Sci (Lond) (1984) 66 (2): 17P.
Does Oxytocin Counteract the Inhibitory Activity of the Hypothalamic Sodium Transport Inhibitor?
Clin Sci (Lond) (1984) 66 (2): 17P–18P.
The Validation of a Cytochemical Bioassay for Arginine Vasopressin and Its Use to Measure Serial Plasma Values in the Preterm Infant
Clin Sci (Lond) (1984) 66 (2): 18P.
Vip-Ergic Innervation of Human Eccrine Sweat Glands: Studies in Axillary Hyperhidrosis
Clin Sci (Lond) (1984) 66 (2): 18P.
Low Frequency Fatigue as a Limiting Factor for Exercise of the Sternomastoid Muscle in Normal Man
Clin Sci (Lond) (1984) 66 (2): 19P.
31 Phosphorus Nuclear Magnetic Resonance Used in a Double Blind Trial of Allopurinol in Duchenne Muscular Dystrophy
Clin Sci (Lond) (1984) 66 (2): 20P.
The Direct Determination of Aluminium in Serum Using a DC Plasma Emission Spectrometer
Clin Sci (Lond) (1984) 66 (2): 20P.
Endogenous Circulating Levels of Vitamin K1 Measured by Means of High-Performance Liquid Chromatography with An Electrochemical Detection System
Clin Sci (Lond) (1984) 66 (2): 21P.
Comparison of the Biological Activity of 25OHD3 and 24, 25(OH)2D3
Clin Sci (Lond) (1984) 66 (2): 21P.
A Thromboxane Antagonist, Ep092, Reduces the Incorporation of Platelets into Fibrin-Rich Thrombi in Rabbits
Clin Sci (Lond) (1984) 66 (2): 22P.
Endogenous and Exogenous Inflammatory Mediators Cause Secretion of 35SO4-Labelled Macromolecules from Ferret Trachea
Clin Sci (Lond) (1984) 66 (2): 23P.
Prostaglandin E2 Modulates Cholinergic Neurotransmission in Canine Tracheal Muscle
Clin Sci (Lond) (1984) 66 (2): 23P–24P.
The Importance of Calcium and Calmodulin in Prostacyclin Production by Cultured Vascular Endothelial Cells
Clin Sci (Lond) (1984) 66 (2): 24P.
The Effect of Interactions with Leukocyte Elastase on the Quantitation of α-1-Proteinase Inhibitor by Rocket Immunoelectrophoresis
Clin Sci (Lond) (1984) 66 (2): 24P–25P.
Degenerative Myelopathy in German Shepherd Dogs: An Association with Mucosal Piochemical Changes and Bacterial Overgrowth in the Small Intestine
Clin Sci (Lond) (1984) 66 (2): 25P.
The Influence of High Fat Diet on the Proteinuria in Puromycin Induced Nephrotic Syndrome in Rats
Clin Sci (Lond) (1984) 66 (2): 26P.
Development and Use of Recombinant Dna Probes for Linkage Analysis to X-Linked Retinitis Pigmentosa
Clin Sci (Lond) (1984) 66 (2): 26P–27P.
The Relationship between Platelet and Megakaryocyte Volume in Acute Myocardial Infarction
Clin Sci (Lond) (1984) 66 (2): 27P.
The Non-Invasive Assessment of Left Ventricular Performance Using Doppler Ultrasound
Clin Sci (Lond) (1984) 66 (2): 27P–28P.
Echocardiographic Assessment of Left Ventricular Function in Relation to Thiamine Status in Alcoholic and Non-Alcoholic Liver Disease
Clin Sci (Lond) (1984) 66 (2): 28P.
The Effect of Hyperkalaemia on the Class Iii Antiarrhythmic Action of Sotalol in Rabbit Ventricular Myocardium
Clin Sci (Lond) (1984) 66 (2): 29P.
Myocardial Glycogen Repletion Outlines Previously Ischaemic Zones in Anginal Patients
Clin Sci (Lond) (1984) 66 (2): 29P.
The Effects of Intravenous Sodium Cromoglycate on Bronchoconstriction Induced by Sulphur Dioxide
Clin Sci (Lond) (1984) 66 (2): 30P.
Immediate Ventilatory and Cardiac Output Changes Due to Lower Limb Positive Pressure Administered with “Medical Antishock Trousers”
Clin Sci (Lond) (1984) 66 (2): 31P.
Breathlessness during Reflex and Voluntary Stimulation of Breathing; a Study of Mechanisms in Normals
Clin Sci (Lond) (1984) 66 (2): 31P.
The Relationship between Small Airways Dysfunction and Lung Epithelial Permeability in Cigarette Smokers
Clin Sci (Lond) (1984) 66 (2): 31P–32P.
Does Aminophylline Improve Exercise Tolerance in Chronic Obstructive Pulmonary Disease
Clin Sci (Lond) (1984) 66 (2): 32P.
Angiotensin Converting Enzyme Response to Hypoxia: Its Role in Susceptibility to Acute Mountain Sickness
Clin Sci (Lond) (1984) 66 (2): 32P.
Gastric Emptying of Solid and Liquid Components of a Meal in Erosive Oesophagitis
Clin Sci (Lond) (1984) 66 (2): 32P–33P.
Diagnostic Value of Oesophageal Potential Difference Measurement in Reflux Oesophagitis
Clin Sci (Lond) (1984) 66 (2): 33P.
The Use of Recombinant Dna Techniques to Study the Development of the Mammalian Small Intestinal Epithelium
Clin Sci (Lond) (1984) 66 (2): 33P.
Motility of Intestinal Macrophages in Patients with Colorectal Carcinoma (Ca)
Clin Sci (Lond) (1984) 66 (2): 33P–34P.
Evaluation of the Nitrosamine Hypothesis of Gastric Carcinogenesis in Man
Clin Sci (Lond) (1984) 66 (2): 34P–35P.
The Fate of 125Iodine-Labelled Intrinsic Factor During 57Co-Cyanocobalamin Absorption
Clin Sci (Lond) (1984) 66 (2): 35P.
Inactive Renin Response to Dietary Sodium and Potassium Manipulations in Normal Subjects
Clin Sci (Lond) (1984) 66 (2): 36P–37P.
Developmental Brush Border Defect Associated with Cereal Sensitivity in the Irish Setter Dog
Clin Sci (Lond) (1984) 66 (2): 38P.
Abnormal Circadian Rhythm of Melatonin in Diabetic Autonomic Neuropathy
Clin Sci (Lond) (1984) 66 (2): 38P–39P.
Verapamil in Acute Myocardial Infarction: Effects on Early Ischemic Complications
Clin Sci (Lond) (1984) 66 (2): 39P.
Comparison of Three Techniques for Assessing Hypoxic Drive in Normal Subjects
Clin Sci (Lond) (1984) 66 (2): 42P.
The Effect of Calmodulin and Anti-Calmodulin Drugs on Melanoma Cell Growth
Clin Sci (Lond) (1984) 66 (2): 42P–43P.
Renovascular Distribution of Npy and Its Vasoconstrictor and Natriuretic Properties
Clin Sci (Lond) (1984) 66 (2): 43P.
Hypoglycaemic Action of Glibenclamide in Diabetics: Pharmacokinetic Manipulation of Insulin-Gluccse-Glibenclamide Relationships
Clin Sci (Lond) (1984) 66 (2): 43P–44P.
A Disease Association of Insulin Dependent Diabetes (Iddm) with a Polymorphic Locus on Chromosome 11
Clin Sci (Lond) (1984) 66 (2): 44P.
Once Daily Insulin Treatment in the Elderly Diabetic: A Comparative Study
Clin Sci (Lond) (1984) 66 (2): 44P–45P.
Type III Hyperlipoproteinaemia and Dna Polymorphism around the APO A1-C-III Gene Cluster
Clin Sci (Lond) (1984) 66 (2): 45P.
Human C-Reactive Protein Binds Circulating Very Low Density Lipoproteins
Clin Sci (Lond) (1984) 66 (2): 45P–46P.
Studies on the in Vitro Calcification of Porcine Xenograft Valves and Its Prevention
W.G. Robertson; G.A. Davies; V. Sergeant; N.B. Makins; M. Ward; A. Schofield; D.A. Watson; M. Peacock
Clin Sci (Lond) (1984) 66 (2): 46P.
Regional Cerebral Blood Flow, Blood Volume and Oxygen Utilisation in Occlusive Carotid Artery Disease: Evaluation of Perfusion Reserve
Clin Sci (Lond) (1984) 66 (2): 47P–48P.
Controlled Trial of Prostacyclin in Acute Cerebral Infarction
N. A. T. Hamdy; J. F. Martin; J. Nicholl; P. Owen; N. Lewtas; U. B. Bergvall; D. Whittington; A. M. Holroyd
Clin Sci (Lond) (1984) 66 (2): 48P.
Adenosine May Mediate the Anti-Platelet Aggregatory Effect of Myocardial Ischaemia
Clin Sci (Lond) (1984) 66 (2): 48P.
Preliminary Report of Separate Sites of Iga1 Cleavage by the Streptococcus Sanguis Protease
Clin Sci (Lond) (1984) 66 (2): 49P.
Inhibition of Binding of Serum Amyloid P Component to Amyloid Fibrils, Fibronectin and C4-Binding Protein
Clin Sci (Lond) (1984) 66 (2): 50P.
Tightly Bound Metabolites of the Purine Nucleotide Cycle in Muscle from Dystrophic Mice
Clin Sci (Lond) (1984) 66 (2): 51P.
Limiting Symptoms in Chronic Heart Failure Are Dependent on Rate of Increase of Work Load and Independent of Haemodynamics
Clin Sci (Lond) (1984) 66 (2): 51P.
Haemodynamic Variability at Rest and following Repetitive Upright Dynamic Exercise in Coronary Heart Disease
Clin Sci (Lond) (1984) 66 (2): 52P.
Gold 195M in the Assessment of the Cold Pressor Test by Radionuclide Ventriculography
Iain N Findlay, MRCP; Gerard Gillen, BSC; John Wilson, BSC; Alex T. Elliott, PhD; Henry J. Dargis, MRCP
Clin Sci (Lond) (1984) 66 (2): 52P–53P.
Treatment of Exercise-Induced Ischemia with Bm14.190, a New Beta Blocker with Vasodilating Activity
Clin Sci (Lond) (1984) 66 (2): 53P–54P.
Role of Dynamic Coronary Stenoses in Exertional Angina: Assessment with St Segment/Heart Rate Slopes during Exercise following Vasodilators
Clin Sci (Lond) (1984) 66 (2): 54P.
Measurement of Unilateral Pulmonary Blood Flow in Patients with Carcinoma of the Bronchus
Clin Sci (Lond) (1984) 66 (2): 54P.
The Effect of Nebulised Lignocaine and Intravenous Diazepam on Po2, Airflow, and Cardiac Rhythm during Fibreoptic Bronchoscopy
Clin Sci (Lond) (1984) 66 (2): 54P–55P.
Bronchoalveolar Lavage in Fibrosing Alveolitis Assessment of Lymphocyte Proportions, Subtypes and Function
Clin Sci (Lond) (1984) 66 (2): 55P.
Breathlessness of Hypoxaemia Attributable Only to Stimulation of Breathing without An Additional “Dyspnogenic” Effect
Clin Sci (Lond) (1984) 66 (2): 55P–56P.
Breathlessness during Progressive and Steady State Exercise in Normal Subjects
Clin Sci (Lond) (1984) 66 (2): 56P.
Correlates of 6 Min Walking Distance and Maximal Oxygen Uptake in Chronic Lung Disease
Clin Sci (Lond) (1984) 66 (2): 57P.
Methylxanthines and Adrenaline-Induced Hypokalaemia - Possible Contribution to Tachyarrhythmias in Asthmatic Patients?
Clin Sci (Lond) (1984) 66 (2): 57P.
Attenuation by Propranolol of the Airway and Cardiovascular Responses to Oral Theophylline in Normal Subjects
Clin Sci (Lond) (1984) 66 (2): 57P–58P.
The Bronchodilating Effects of Intravenous Vasoactive Intestinal Peptide in Human Asthmatic Subjects
Clin Sci (Lond) (1984) 66 (2): 58P.
New Device for Airflow Measurement: Comparison with Pneumotachograph and Differentiated Respitrace Volume
Clin Sci (Lond) (1984) 66 (2): 58P.
Biliary Excretion of Vitamin D Metabolites following Oral and Intravenous Vitamin D
Clin Sci (Lond) (1984) 66 (2): 58P–59P.
Reappraisal of the ‘Lectin Hypothesis’ in the Aetiopathogenesis of Coeliac Disease
Clin Sci (Lond) (1984) 66 (2): 59P.
Acetate and Citrate Stimulate Net Water and Sodium Absorption from the Human Jejunum
Clin Sci (Lond) (1984) 66 (2): 59P–60P.
Oestrogens Increase Permeability of Bile Canalicular Tight Junctions without Affecting the Static Negative Charge
Clin Sci (Lond) (1984) 66 (2): 60P.
Serum Neuraminidase and Sulphatase Inhibition in Health and in Inflammatory Bowel Disease
Clin Sci (Lond) (1984) 66 (2): 60P.
Reduced Brain Na+,K+-Atpase Activity during Acute Hepatic Failure in the Rat: A Possible Cause of Encephalopathy and Cerebral Oedema
Clin Sci (Lond) (1984) 66 (2): 62P.
Does Intraluminal Hydrocortisone Stimulate Glucose-Coupled Sodium Transport in the Human Jejunum?
Clin Sci (Lond) (1984) 66 (2): 62P.
Dietary Potassium Loading Increases Intracellular Potassium Activity and Apical Cell Membrane Potassium Conductance in Distal Colon
Clin Sci (Lond) (1984) 66 (2): 63P.
Intestinal Permeability to 51Cr Edta in Rats with Experimentally-Induced Enteropathy
Clin Sci (Lond) (1984) 66 (2): 63P.
Jejunal Transglutaminase: Demonstration of Activity, Enzyme Kinetics, Substrate Specificity and Levels in Patients with Coeliac Disease
Clin Sci (Lond) (1984) 66 (2): 64P.
Biochemical and Cytochemical Studies of Rat Duodenal and Ileal Hco3−-Atpase Activities
Clin Sci (Lond) (1984) 66 (2): 64P.
Studies on the Distribution of Hepatocytes in Rats following Rapid Intravenous Infusion via the Jugular Vein
Clin Sci (Lond) (1984) 66 (2): 65P.
Dopamine, Noradrenaline and Adrenaline in the Adrenal Medulla and Cortex of the Rat
Clin Sci (Lond) (1984) 66 (2): 65P.
The Use of Nifedipine in Combination Therapy for the Management of Hypertension
Clin Sci (Lond) (1984) 66 (2): 66P.
Moderate Intakes of Eicosapentaenoic Acid (Epa) and Docosahexaenoic Acid (Dha) May Mitigate Salt Induced Hypertension in the Rat
Clin Sci (Lond) (1984) 66 (2): 66P.
Duration and Diurnal Variation of the Hypotensive Effect of Enalapril in Patients with Essential Hypertension
Clin Sci (Lond) (1984) 66 (2): 66P.
The Influence of Dietary Potassium Supplementation on the Development of Hypertension in the Spontaneously Hypertensive Rat (Shr)
Clin Sci (Lond) (1984) 66 (2): 67P.
Importance of Direct Measurement of Plasma Colloid Osmotic Pressure in Critically Ill Patients
Clin Sci (Lond) (1984) 66 (2): 67P.
Studies on Regional Blood-Brain Barrier Permeability in Patients Using 82Rb+, 11C-Methyl-Albumin and Positron Emission Tomography
Clin Sci (Lond) (1984) 66 (2): 68P.
The Effects of Dopamine Agonists on Regional Cerebral Blood Flow and Oxygen Metabolism in Patients with Parkinson's Disease and Normal Volunteers
Clin Sci (Lond) (1984) 66 (2): 68P–69P.
Alterations in the Responses of Circulating Tsh, Prolactin and Aldosterone Levels to Metoclopramide in Hypothyroidism Due to Warming
Clin Sci (Lond) (1984) 66 (2): 70P.
An Investigation of Neuroendocrine and Cardiovascular Effects of Substance P Micro-Injected into the Nucleus Tractus Solitarii
Clin Sci (Lond) (1984) 66 (2): 70P–71P.
Vascular Distribution of a Potent Vasoconstrictor Peptide, Neuropeptide Y (Npy)
Clin Sci (Lond) (1984) 66 (2): 71P.
The Effect of Nou-Esterified Fatty Acids on Vascular Adp-Degeading Enzyme (Adpase) Activity
Clin Sci (Lond) (1984) 66 (2): 72P.
Evidence That Human Neutrophil Alkaline Phosphatase Has the Same Biochemical Characteristics as the Liver / Bone / Kidney Isoenzyme
Clin Sci (Lond) (1984) 66 (2): 72P–73P.
Erythrocyte 5-Aminolaevulinic Acid Dehydrase Hydroxymethylbilane Synthase and Uroporphyrinogen Iii Synthase Activities in Alcoholics
Clin Sci (Lond) (1984) 66 (2): 73P.
Localisation of Intracellular Copper in Liver and Kidney during the Development of Copper Tolerance in the Rat
Clin Sci (Lond) (1984) 66 (2): 74P.
Changes in Hepatic Cytochrome P-450 Concentrations in Allergic Arthritis in Rabbits: A Microspectrophotometric Study
Clin Sci (Lond) (1984) 66 (2): 75P.
Kinetics of the Humoral Immune Response in Mice Experimentally Infected with Trypanosoma Cruzi
Clin Sci (Lond) (1984) 66 (2): 76P.
Strategies for the Generation of Monoclonal Antibodies against Human Pancreatic Exocrine Cancer
Clin Sci (Lond) (1984) 66 (2): 76P.
Objective Monitoring of Disease Activity in Wegener's Granulomatosis by Measurement of Serum C-Reactive Protein Concentration
Clin Sci (Lond) (1984) 66 (2): 76P.
The Mononuclear Cells of Human Mesenteric Blood, Intestinal Mucosa, and Mesenteric Lymph Nodes: Compartmentalization of Nk Cells
Clin Sci (Lond) (1984) 66 (2): 77P.
Isolation of Intestinal Mononuclear Cells: Factors Released Which Affect Lymphocyte Viability and Function
Clin Sci (Lond) (1984) 66 (2): 77P.
Failure of Dopamine Blockade to Attenuate the Rise in Arginine Vasopressin Due to Increased Plasma Osmolality
Clin Sci (Lond) (1984) 66 (2): 77P.
Editorial Review
Articles
The Antihypertensive Effect of Dietary Potassium Chloride Loading in Rats with Adrenal Regeneration Hypertension
Clin Sci (Lond) (1984) 66 (2): 129–140.
The Influence of Acute Starvation on the Cardiovascular Responses to Lower Body Subatmospheric Pressure or to Standing in Man
Clin Sci (Lond) (1984) 66 (2): 141–146.
Glycine Pools and Turnover Rates in Leukaemia Patients Measured with [15N]Glycine
Clin Sci (Lond) (1984) 66 (2): 147–154.
The Measurement of Whole Body Protein Turnover in the Preterm Infant with Intragastric Infusion of l-[1-13C]Leucine and Sampling of the Urinary Leucine Pool
Clin Sci (Lond) (1984) 66 (2): 155–164.
Prostaglandins Cause An Increase in Serum Acute-Phase Proteins in Man, Which is Diminished in Systemic Sclerosis
Clin Sci (Lond) (1984) 66 (2): 165–171.
Fatty Acid Oxidation in Mitochondria from Needle Biopsy Samples of Human Skeletal Muscle
Clin Sci (Lond) (1984) 66 (2): 173–178.
Ephedrine-Induced Thermogenesis in Man: No Role for Interscapular Brown Adipose Tissue
Clin Sci (Lond) (1984) 66 (2): 179–186.
Hypercalcaemia of Malignancy: Evidence for a Non-Parathyroid Humoral Agent with An Effect on Renal Tubular Handling of Calcium
Clin Sci (Lond) (1984) 66 (2): 187–191.
Urinary Adenosine Cyclic 3′,5′-Monophosphate in Idiopathic Calcium Stone-Formers: Response to An Oral Calcium Load
Clin Sci (Lond) (1984) 66 (2): 193–199.
Effect of Molecular Charge on the Induction of Proteinuria and Glomerular Ultrastructural Damage in Hyperalbuminaemic Female Wistar Rats
Clin Sci (Lond) (1984) 66 (2): 201–206.
Release of Active and Inactive Kallikrein from the Isolated Perfused Rat Kidney
Clin Sci (Lond) (1984) 66 (2): 207–215.
The Effect of Leucocyte Elastase on the Immunoelectrophoretic Behaviour of α1-Antitrypsin
Clin Sci (Lond) (1984) 66 (2): 217–224.
Effect of High Sodium Intake on Tissue Distribution of Endogenous Digitalis-Like Material in the Rat
Clin Sci (Lond) (1984) 66 (2): 225–228.
Short Communication
The Importance of Urinary Immunoglobulin Light Chain Isoelectric Point (Pi) in Nephrotoxicity in Multiple Myeloma
Clin Sci (Lond) (1984) 66 (2): 229–232.
Baroreflex Setting and Sensitivity after Acute and Chronic Nicardipine Therapy
Clin Sci (Lond) (1984) 66 (2): 233–235.
The Dilator Response to K+ Is Reduced in the Forearm Resistance Vessels of Men with Primary Hypertension
Clin Sci (Lond) (1984) 66 (2): 237–239.