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December 1984
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ISSN 0143-5221
EISSN 1470-8736
Medical Research Society Meeting 12th and 13th July 1984
Communication
Improvement in Systolic and Diastolic LV Function in Patients with Chronic Congestive Heart Failure Treated with Nicardipine
Clin Sci (Lond) (1984) 67 (s9): 1P.
Right Ventricular Necrosis in Inferior Myocardial Infarction; A Comparison of Non-Invasive Diagnostic Methods
Clin Sci (Lond) (1984) 67 (s9): 1P.
Effect of Mioflazine OH Ca++ Localization and Infarct Size: A Study in Langendorff–Perfused Cat Hearts
Clin Sci (Lond) (1984) 67 (s9): 2P.
The Effect of Felodipine on Blood Pressure, Heart Rate, Forearm Blood Flow and the Response to Venous Occlusion in Normal Man
Clin Sci (Lond) (1984) 67 (s9): 3P.
Measurement of Aoptic Blood Velocity in Acute Myocardial Infarction by Doppler Ultrasound
Clin Sci (Lond) (1984) 67 (s9): 4P.
The Effects of Hydrogen Peroxide on the Anti-Elastolytic Properties of Serum from Emphysematous Patients and Healthy Controls
Clin Sci (Lond) (1984) 67 (s9): 5P.
The Influence of Resting Airway Calibre on Non-Specific and Specific Airway Reactivity in Asthma
Clin Sci (Lond) (1984) 67 (s9): 5P–6P.
The Effect of Prostacyclin on Alveolar-Capillary Membrane Permeability following Cardiopulmonary By-Pass
Clin Sci (Lond) (1984) 67 (s9): 6P.
Use of the Forced Oscillation Technique to Measure Transient Changes in Airways Impedance
Clin Sci (Lond) (1984) 67 (s9): 7P.
Effects of Diazepam and Chlormethiazole on Ventilatory Control in Normal Subjects
Clin Sci (Lond) (1984) 67 (s9): 8P.
Ventilatory Mechanics during Sustained Maximum Voluntary Ventilation and Exercise in Patients with Chronic Airflow Limitation
Clin Sci (Lond) (1984) 67 (s9): 9P.
Caeruloplasmin in Serum and Bronchoalveolar Lavage Fluid of Smokers and Non-Smokers
Clin Sci (Lond) (1984) 67 (s9): 9P–10P.
Failure of Glucose to Reverse the Jejunal Secretory State in Chronic Idiopathic Intestinal Pseudo-Obstruction (IIP)
Clin Sci (Lond) (1984) 67 (s9): 11P.
Hepatic and Intestinal Bile Acid (BA) Transport during Total Parenteral Nutrition (TPN) in the Rat
Clin Sci (Lond) (1984) 67 (s9): 12P.
Serum High-Density Lipoprotein (HDL) Sub-Fractions in Non-Minimal Change Nephrotic Syndrome (NMCNS)
Clin Sci (Lond) (1984) 67 (s9): 12P–13P.
Direct Demonstration of An Inhibitor of Na+K+Atpase in Plasma from Normotensive and Hypertensive Subjects
Clin Sci (Lond) (1984) 67 (s9): 13P.
Plasma Dicarboxylic Acid Concentrations in Uncontrolled Diabetes Mellitus and the Effects of Treatment
Clin Sci (Lond) (1984) 67 (s9): 13P–14P.
Oesophageal Dysfunction in Diabetes Mellitus and Its Association with Autonomic Neuropathy
Clin Sci (Lond) (1984) 67 (s9): 14P.
Sialidase Activity Acting on Apolipoprotein CIII 1 and 2 in Human Leukocytes and Platelets
Clin Sci (Lond) (1984) 67 (s9): 15P.
Inhibitory Effect of 3-Hydroxybutyrate on Lactate Binding of Rat Hepatocyte Plasma Membranes and on Lactate Transport into Isolated Rat Hepatocytes
Clin Sci (Lond) (1984) 67 (s9): 15P.
Inhibition of Urea and Glucose Production by Acetazolahide in Isolated Rat Hepatocytes
Clin Sci (Lond) (1984) 67 (s9): 15P–16P.
Hyperteiglyceridaemia and Abnormalities of Triglyceride Catabolism in Patients with Previous Pancreatitis
Clin Sci (Lond) (1984) 67 (s9): 16P.
Severity of Alcohol Dependence in a General Hospital Sample of Problem Drinkers
Clin Sci (Lond) (1984) 67 (s9): 16P–17P.
Endogenous Gastric Inhibitory Polypeptide (GIP) Does Not Affect Removal of Triacylglycerol from Plasma in Man
Clin Sci (Lond) (1984) 67 (s9): 18P.
The Influence of the Adrenal Cortex on Adrenaline Release by the Adrenal Medulla in Man
Clin Sci (Lond) (1984) 67 (s9): 18P–18.
Can Serum Thyroglobulin Predict Immediate Relapse in Graves Disease When Discontinuing Carbimazole?
Clin Sci (Lond) (1984) 67 (s9): 19P.
Neuropeptide Y in the Human Circle of Willis and Its Effect on Cerebral Cortical Blood Flow
Clin Sci (Lond) (1984) 67 (s9): 19P.
The Effect of Enkephalin Analogue (DAMME) on Pituitary Hormone Release in Human Obesity
Clin Sci (Lond) (1984) 67 (s9): 19P–20P.
Lectin Affinity Chromatography of Rat Gonado Trophins in Vivo and in Vitro
Clin Sci (Lond) (1984) 67 (s9): 20P.
Localisation of Enlarged Parathyroid Glands Using 99mtc Pertechnetate and 201Tl Thallous Chloride Scans
Clin Sci (Lond) (1984) 67 (s9): 20P.
Adenylate Cyclase in the Chick Duodenal Cell: Vtllar Localisation and Effect of 1,25-Dihydroxy Vitamin D3
Clin Sci (Lond) (1984) 67 (s9): 20P–21P.
Bone Density Trends in the Distal Radius Correlate with An Index of Axial Osteoblast Depression in Osteoporosis
Clin Sci (Lond) (1984) 67 (s9): 21P.
Simultaneous Determination of Plasma 25 Hydroxy Vitamins D2 and D3 by High Performance Liquid Chromatography in Metabolic Bone Disease
Clin Sci (Lond) (1984) 67 (s9): 21P.
Calcium Metabolism in Osteogenesis Imperfecta
P.J. Lawson-Matthew; A. Challa; J.C. Clayton; D.F. Guilland-Cumming; M.K.B. McGuire-Goldring; A.M. Caswell; D.L. Douglas; R.G.G. Russell; J.A. Kanis
Clin Sci (Lond) (1984) 67 (s9): 21P–22P.
Beneficial Effect of Isa on Renal Haemodynamics and Sodium Excretion during Beta Blockade
Clin Sci (Lond) (1984) 67 (s9): 22P.
Optimized Conditions for Trypsin Activation of Inactive Renin in Human Plasma
Clin Sci (Lond) (1984) 67 (s9): 22P.
Gludopa and Renal Function in Normal Man: A Placebo Controlled Trial
Clin Sci (Lond) (1984) 67 (s9): 22P–23P.
Impaired Sodium Excretion during Water Immersion in Diabetes Mellitus: Observations on the Renin-Aldosterone System
Clin Sci (Lond) (1984) 67 (s9): 23P.
Quantitative Measurement of Tremor in Hyperthyroidism: Effects of Nadolol and Carbimazole
Clin Sci (Lond) (1984) 67 (s9): 24P.
Serum C-Reactive Protein in the Rapid Diagnosis of Bacterial Infection during Sickle Cell Crisis: A Preliminary Report
Clin Sci (Lond) (1984) 67 (s9): 25P.
The Effects of Hydrogen Peroxide on the Anti-Elastolytic Properties of Serum from Patients with Rheumatoid Arthritis
Clin Sci (Lond) (1984) 67 (s9): 25P.
Restriction Fragment Length Polymorphism (RFLP) Analysis of the Insulin and Apoprotein C-II Genes in Different Populations
Clin Sci (Lond) (1984) 67 (s9): 26P.
Partial Purification of the Hypothalamic Sodium Transport Inhibitor
Clin Sci (Lond) (1984) 67 (s9): 27P.
Specific Thromboxane Synthetase Inhibition and Microalbumin Excretion Rate in Insulin Dependent Diabetics
Clin Sci (Lond) (1984) 67 (s9): 27P.
Increased Lung Epithelial Permeability to Histamine is Mediated by H2 Receptors
Clin Sci (Lond) (1984) 67 (s9): 27P–28P.
Localised Reentry within the Left Posterior Fascicle Responsive to Calcium Antagonists - A Mechanism of Sustained Ventricular Tachycardia
Clin Sci (Lond) (1984) 67 (s9): 29P.
Force Interval Relationships in the Human Heart Studied in Vivo and in Vitro
Clin Sci (Lond) (1984) 67 (s9): 30P.
A Possible Explanation for the Absence of Anti-Anginal Properties with Transdermal Nitroglycerin Units
Clin Sci (Lond) (1984) 67 (s9): 30P.
Cellular Electrophysiology of Adenosine and 8 Phenyltheophylline during Myocardial Ischaemia and Reperfusion
Clin Sci (Lond) (1984) 67 (s9): 30P–31P.
Measurement of Stroke Volume, Peak Velocity and Acceleration of Aortic Blood flow at Rest and on Exercise in Man By Range-Gated Ultrasound
Clin Sci (Lond) (1984) 67 (s9): 31P.
24 Hour Changes in Heart Rate of the Transplanted and Innervated Human Hearts
Clin Sci (Lond) (1984) 67 (s9): 31P.
Different Mechanisms for Pain Relief following Coronary Surgery
P. Ribeiro; M. J. Shea; J. E. Deanfield; C. M. Oakley; R. Sapsford; T. Jones; R. Walesby; A. P. Selwyn
Clin Sci (Lond) (1984) 67 (s9): 31P–32P.
Effect of Hyperventilation during Exercise on Oxygen Consumption and Co2 Production Measured at the Mouth
Clin Sci (Lond) (1984) 67 (s9): 32P.
The Influence of Non-Specific Airway Reactivity on the Immediate Bronchoconstrictor Response to Exercise and Antigen in Asthma
Clin Sci (Lond) (1984) 67 (s9): 33P.
Lung Scan Observations on the Mechanism of Hypoxaemia in Acute Minor Pulmonary Embolism
Clin Sci (Lond) (1984) 67 (s9): 33P–34P.
Acetylcholinesterase Inhibition: A Probe for Investigating Cholinergic Control of Human Airways
Clin Sci (Lond) (1984) 67 (s9): 34P.
Plasma Catecholamine Concentrations in Acute Severe Asthma and Antigen-Induced Bronchoconstriction
Clin Sci (Lond) (1984) 67 (s9): 34P–35P.
Ursocholic Acid (UCA): A New Cholesterol (CH) Gallstone Dissolving Agent? Bile Acid and Bile Lipid Dose-Response Studies in Man
Clin Sci (Lond) (1984) 67 (s9): 35P–36P.
The Subcellular Distribution and Levels of Calmodulin in Jejunal Biopsies from Control Subjects and Patients with Coeliac Disease
Clin Sci (Lond) (1984) 67 (s9): 36P.
Acarbose-Induced Elevation of Plasma Enteroglucagon Does Not Inhibit Pentagastrin Stimulated Gastric Acid Secretion in the Rat
Clin Sci (Lond) (1984) 67 (s9): 37P.
Antigenic Reactivity of Gluten Peptides Prepared by High Pressure Liquid Chromatography
Clin Sci (Lond) (1984) 67 (s9): 37P–38P.
Auto-Immunity Induced by Homologous Glomerular Basement Membrane Alone in the Brown Norway Rat
Clin Sci (Lond) (1984) 67 (s9): 38P.
Immunological Studies on Glomerular Basement Membrane in Alport's Syndrome
C.O.S. Savage; C.D. Pusey; M. Kershaw; P. Harrison; J.S. Cameron; D.R. Turner; S. Cashman; D.J. Evans; D.K. Peters; C.M. Lockwood
Clin Sci (Lond) (1984) 67 (s9): 38P.
Effect of Fish Oil (FO) on Plasma Lipids (PL), Platelet Fatty Acids (PFA) and Platelet Function in Chronic Renal Failure(CRF)
Clin Sci (Lond) (1984) 67 (s9): 39P.
Effects of High and Low Molecular Weight Forms of Atrial Natriuretic Factor in the Isolated Kidney
Clin Sci (Lond) (1984) 67 (s9): 39P.
Changes in Leucocyte Sodium Transport with Alterations in Sodium balance: A Qualitative Difference in Normotensive Relatives of Hypertensives Compared to Controls
Clin Sci (Lond) (1984) 67 (s9): 39P–40P.
25-Hydroxy Vitamin D Deficiency Does Not Account for Impaired Quadriceps Strength in Asians
Clin Sci (Lond) (1984) 67 (s9): 40P.
Intravenous Clodronate in the Treatment and Retreatment of Paget's Disease
A.J.P. Yates; C.J. Preston; R.C. Percival; R.E.S. Gray; R.M. Atkins; G.H. Urwin; R.G.G. Russell; J.A. Kanis
Clin Sci (Lond) (1984) 67 (s9): 40P–41P.
Inhibition of Sodium Pump Activity by Physiological Doses of Noradrenaline in Human Leucocytes and Rat Aortae
Clin Sci (Lond) (1984) 67 (s9): 41P.
Selective Inhibition of Intestinal Disaccharide Absorption by Deoxynojirimycin-Derived Glycosidase Inhibitors
Clin Sci (Lond) (1984) 67 (s9): 41P–42P.
Impaired Lv Function in Acute Myocardial Infarction (AMI), Assessed Non-Invasively by Doppler Ultrasound
Clin Sci (Lond) (1984) 67 (s9): 42P.
Cation Uptake as a Measure of Regional Myocardial Blood Flow: Direct Validation in Patients with Infarction
A. P. Selwyn; M. J. Shea; R. Wilson; J. E. Deanfield; C. De Landsheere; D. Turton; F. Brady; V. Pike
Clin Sci (Lond) (1984) 67 (s9): 43P.
The Effect of End Tidal Pco2 on the Response of Airways Impedance to Hyperventilation
Clin Sci (Lond) (1984) 67 (s9): 43P.
Brkathlessness in Respiratory Patients is Greater with Reflexly-Stimulated than with Voluntary Hyperventilation
Clin Sci (Lond) (1984) 67 (s9): 44P.
Improvement in Insulin Resistance with Longterm Insulin Therapy is Related to C-Peptide Level
Clin Sci (Lond) (1984) 67 (s9): 45P.
Plasma Insulin Concentration in Fasting Non-Diabetics is Higher Standing than Lying
Clin Sci (Lond) (1984) 67 (s9): 45P.
Characteris Ation of the Proteolytic Enzymes Involved in the Conversion of Proinsulin to Insulin
Clin Sci (Lond) (1984) 67 (s9): 45P–46P.
Effect of Pyridoxlne on Oxalate Dynamlcs in Pyridoxins Responsive Primary Hyperoxaluria
Clin Sci (Lond) (1984) 67 (s9): 46P.
Purine De Novo Synthesis in Peripheral Mononuclear Cells and Hepatic Dysfunction
Clin Sci (Lond) (1984) 67 (s9): 47P.
Effect of Cimetidine on Carbamazepin Auto-and Hetero-Enzyme Induction in Man
Clin Sci (Lond) (1984) 67 (s9): 48P.
Influence of Metkephamid, a δ Opioid Receptor Agonist, on Cardiovascular and Autonomic Function in Man
Clin Sci (Lond) (1984) 67 (s9): 49P.
Effect of β-Adrenoreceptor Blockade on Lipoprotein Metabolism in Hypertriglyceridaemic Patients and Normal Men
Clin Sci (Lond) (1984) 67 (s9): 49P.
Desensitisation of Platelet Alpha2 Adrenoceptors Following Short Term Adrenoceptor Agonist Infusions in Man
Clin Sci (Lond) (1984) 67 (s9): 49P–50P.
Prostaglandin Synthetase Inhibition Attenuates the Vasodilator Properties of Nitroglycerin
Clin Sci (Lond) (1984) 67 (s9): 50P.
The Effect of Anti-Inflammatory Agents on Release of Elastase from Human Neutrophils in Vitro
Clin Sci (Lond) (1984) 67 (s9): 51P.
Circulating Antibodies against the Asialo-Glycoprotein Receptor (Hepatic Lectin) in Chronic Liver Disease
Clin Sci (Lond) (1984) 67 (s9): 51P–52P.
Granulocytes and Slow Reacting Substances (SRS) in High Permeability Lung Oedema of Adult Respiratory Distress Syndrome (ARDS)
A. Hussein; J. Loyd; P. Tagari; H. Chapel; G. de J. Lee; M. Buchanan; R. Butt; G. Coates; H. O'brodovich
Clin Sci (Lond) (1984) 67 (s9): 52P.
Low Plasma C4 Concentrations: Association with Microangiopathy in Insulin Dependent Diabetics
Clin Sci (Lond) (1984) 67 (s9): 53P.
Evidence of Impaired Exercise Tolerance in Young Insulin-Dependent Diabetics without Cardiac or Autonomic Abnormalities
Clin Sci (Lond) (1984) 67 (s9): 54P.
A Simple Semi-Automated Technique for Estimating Left Ventricular Volumes by Two Dimensional Echocardiography
Clin Sci (Lond) (1984) 67 (s9): 54P.
The Clinical Role of Thallium-201 Scintigraphy in the Management of Coronary Artery Disease
Clin Sci (Lond) (1984) 67 (s9): 54P–55P.
The Use of 2D-Echocardiography in Evaluation of Myocardial Function after Acute Infarction
Clin Sci (Lond) (1984) 67 (s9): 55P.
Effects of β Adrenergic Antagonists on Intracellular Na & K in Unstimulated Heart and Skeletal Muscle
Clin Sci (Lond) (1984) 67 (s9): 56P.
Assessment of Lipid Status following Acute Myocardial Infarction
Clin Sci (Lond) (1984) 67 (s9): 56P.
Effect of Acute and Chronic Beta Blockade on Arrhythmogenesis and Electrophysiology during Myocardial Ischaemia and Reperfusion
Clin Sci (Lond) (1984) 67 (s9): 56P.
Nisoldipine: A New Calcium Antagonist Effective in the Prevention of Coronary Artery Spasm
Clin Sci (Lond) (1984) 67 (s9): 57P.
Prolonged Arterial and Veno-Dilator Effects of Oral Isosorbide-5-Mondnitrate in Normals and Patients with Acute Myocardial Infarction
Clin Sci (Lond) (1984) 67 (s9): 57P.
Changes in Breathing Pattern after Low Doses of Almitrine Bismesylate in Rats during Acute Hypoxia/Hypercapnia
Clin Sci (Lond) (1984) 67 (s9): 58P.
Effect of Fenoterol 2.5 Mgs and Ipratropium 500 Ug on Pefr and Breathing Patterns in Acute Asthma
Clin Sci (Lond) (1984) 67 (s9): 58P.
Regional Ventilation Perfusion Ratio and Specific Ventilation in Asthmatics Using Positron Emission Tomography (PET)
Clin Sci (Lond) (1984) 67 (s9): 59P–60P.
Effect of Alveolar Pressure on Pulmonary Artery Pressure in a Rat Model of Chronic Hypoxic Lung Disease
Clin Sci (Lond) (1984) 67 (s9): 61P.
Can Verapamil Reverse the Effect of Chronic Hypoxia on the Pulmonary Circulation in Rats?
Clin Sci (Lond) (1984) 67 (s9): 61P.
Is the Potentiation of Diaphragmatic Contractility by Theophylline Dependent on Extracellular Ca++?
Clin Sci (Lond) (1984) 67 (s9): 62P.
The Effect of Air Ionisation on Lung Function in Chronic Asthmatics
Clin Sci (Lond) (1984) 67 (s9): 62P–63P.
Intestinal Monosaccharide Transport is Unimpaired by Deoxynojirimycin-Derived Glycosidase Inhibitors
Clin Sci (Lond) (1984) 67 (s9): 63P.
Comparison of Four Different Markers of Human Intestinal Permeability: (I) Effect of Detergent and Test Dose Osmolarity
Clin Sci (Lond) (1984) 67 (s9): 65P.
Intestinal Permeability and Transglutaminase Alterations in Methotrexate-Induced Enteropathy in the Rat
Clin Sci (Lond) (1984) 67 (s9): 65P.
Pth and 1,25(OH)2D3 Responses to Reduction of Serum Phosphate in Advanced Chronic Renal Failure
Clin Sci (Lond) (1984) 67 (s9): 65P–66P.
The Interrelations between Erythrocyte Lithium Efflux Hypertension and a Family History of Hypertension
Clin Sci (Lond) (1984) 67 (s9): 66P.
Platelet Aggregation in Type 2 (Non-Insulin Dependent) Diabetes is Associated with Plasma Cholesterol and Platelet Fatty Acids
Clin Sci (Lond) (1984) 67 (s9): 66P–67P.
Low HDL2/HDL3 Ratio and Impaired Intravenous Fat Tolerance in Young Smokers
Clin Sci (Lond) (1984) 67 (s9): 68P.
A Possible Role for Gip in the Differential Response to Oral and Intravenous Glucose in the Transplantable Rat Insulinoma - A Role for Gip
Clin Sci (Lond) (1984) 67 (s9): 68P.
Metabolic Effects of Conversion from Cyclosporin a (CYA) to Azathtoprine (AZA) in Renal Transplant Recipients
Clin Sci (Lond) (1984) 67 (s9): 70P.
Effect of Triiodothyronine (T3) on Glucose Production Rate During Starvation
Clin Sci (Lond) (1984) 67 (s9): 70P.
13CO2 Recovery in Expired Air Following the Intravenous Administration of 13C-Sodium Bicarbonate
Clin Sci (Lond) (1984) 67 (s9): 70P–71P.
Abnormal Sodium-Potassium Transport in a Mouse Colonic Adenocarcinoma Cell Line
Clin Sci (Lond) (1984) 67 (s9): 71P.
Needle Aspiration in the Management of Cystic Lesions of the Thyroid
Clin Sci (Lond) (1984) 67 (s9): 71P.
Serum Inhibitors of Basal and Somatomedin Stimulated 35S Sulphate Uptake by Porcine Cartilage in Vitro
Clin Sci (Lond) (1984) 67 (s9): 72P.
Biliary Radioactivity Excretion after Intra Venous Administration of 3H-1,25-Dihydroxyvitamin D3 in Man
Clin Sci (Lond) (1984) 67 (s9): 73P.
Vitamin D Status and Bone Histomorphometry after Biliopancreatic Bypass for Obesity
Clin Sci (Lond) (1984) 67 (s9): 73P.
Aminohexane Diphosphonate (AHDP) for the Treatment of Paget's Disease
R.M. Atkins; C.J. Preston; A.J.P. Yates; R.C. Percival; R.E.S. Gray; G.H. Urwin; R.G.G. Russell; S. Rosini; S. Harris; M.N.C. Beneton; J.A. Kanis
Clin Sci (Lond) (1984) 67 (s9): 73P–74P.
Disturbance of Human Gastrointestinal Transit by Pain: The Role of Adrenergic Pathways
Clin Sci (Lond) (1984) 67 (s9): 74P–75P.
Adrenaline Causes Potassium Influx in Skeletal Muscle but Potassium Efflux from Cardiac Muscle
Clin Sci (Lond) (1984) 67 (s9): 75P.
Chronic Administration of Panax Ginseng and the Levels of Catecholamines and Camp in Rat Brain and Heart
Clin Sci (Lond) (1984) 67 (s9): 75P–76P.
Thromboxane B2 Concentrations Are Not Reduced in Premature Neonates who Develop Major Intraventricular Haemorrhage
Clin Sci (Lond) (1984) 67 (s9): 76P.
Changes in Platelets and Megakaryocytes in Simulated High Altitude in Rats
Clin Sci (Lond) (1984) 67 (s9): 76P.
Serum C-Reactive Protein Response to Therapeutic Embolisation and Its Possible Role in Management
Clin Sci (Lond) (1984) 67 (s9): 77P.
Reticulocyte Life Span and the Role of the Spleen in Acute Blood Loss Anaemia in the Rat
Clin Sci (Lond) (1984) 67 (s9): 78P.