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Volume 84, Issue 3

March 1993

All Issues

Cover Image

Cover Image

ISSN 0143-5221

EISSN 1470-8736

In this Issue

Editorial Review
GLAXO/MRS Young Investigator Medal
Papers

Editorial Review

Tumour necrosis factor-α: Its role in the metabolic response to sepsis

Tom van der Poll; Hans P. Sauerwein

Clin Sci (Lond) (1993) 84 (3): 247–256.

View Articletitled, Tumour necrosis factor-<em>α</em>: Its role in the metabolic response to sepsis

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GLAXO/MRS Young Investigator Medal

Genetics of a multifactorial disease: Autoimmune type I diabetes mellitus

Richard John Cornall

Clin Sci (Lond) (1993) 84 (3): 257–262.

Abstract

View Articletitled, Genetics of a multifactorial disease: Autoimmune type I diabetes mellitus

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Papers

Cardiovascular responses to a high-fat and a high-carbohydrate meal in healthy elderly subjects

M. B. Sidery; A. J. Cowley; I. A. MacDonald

Clin Sci (Lond) (1993) 84 (3): 263–270.

Abstract

View Articletitled, Cardiovascular responses to a high-fat and a high-carbohydrate meal in healthy elderly subjects

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Paradoxical forearm vasodilatation and haemodynamic improvement during cardiopulmonary baroreceptor unloading in patients with congestive heart failure

Katsuhiko Nishian; Seinosuke Kawashima; Tadaaki Iwasaki

Clin Sci (Lond) (1993) 84 (3): 271–280.

Abstract

View Articletitled, Paradoxical forearm vasodilatation and haemodynamic improvement during cardiopulmonary baroreceptor unloading in patients with congestive heart failure

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Chronic insulin treatment in rats: Evidence against a role for insulin as a pressor agent

Félix Vargas; José Mario Sabio; Miguel Angel Castillo; Juan De Dios Luna; José Manuel Haro; Cipriano García Del Río

Clin Sci (Lond) (1993) 84 (3): 281–286.

Abstract

View Articletitled, Chronic insulin treatment in rats: Evidence against a role for insulin as a pressor agent

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Free-radical scavengers, thiol-containing reagents and endothelium-dependent relaxation in isolated rat and human resistance arteries

W. Sunman; A.D. Hughes; P.S. Sever

Clin Sci (Lond) (1993) 84 (3): 287–295.

Abstract

View Articletitled, Free-radical scavengers, thiol-containing reagents and endothelium-dependent relaxation in isolated rat and human resistance arteries

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Lack of effect of peripheral nervous blockade on nocturnal fluctuations in lower-leg subcutaneous blood flow in man

J. H. Sindrup; L. J. Petersen; J. Kastrup; H. Wroblewski; J. K. Kristensen

Clin Sci (Lond) (1993) 84 (3): 297–304.

Abstract

View Articletitled, Lack of effect of peripheral nervous blockade on nocturnal fluctuations in lower-leg subcutaneous blood flow in man

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Cerebrospinal fluid levels of substance P and calcitonin-gene-related peptide: Correlation with sural nerve levels and neuropathic signs in sensory diabetic polyneuropathy

C. Tsigos; L. T. Diemel; A. White; D. R. Tomlinson; R. J. Young

Clin Sci (Lond) (1993) 84 (3): 305–311.

Abstract

View Articletitled, Cerebrospinal fluid levels of substance P and calcitonin-gene-related peptide: Correlation with sural nerve levels and neuropathic signs in sensory diabetic polyneuropathy

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Possible long-lasting inhibition of converting enzyme by enalapril in human cerebrospinal fluid

Marcello Fanciullacci; Massimo Alessandri; Maria Nicolodi; Sergio Michelacci; Federigo Sicuteri

Clin Sci (Lond) (1993) 84 (3): 313–317.

Abstract

View Articletitled, Possible long-lasting inhibition of converting enzyme by enalapril in human cerebrospinal fluid

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Nocturnal desaturation and serum erythropoietin: A study in patients with chronic obstructive pulmonary disease and in normal subjects

Michael F. Fitzpatrick; Tom MacKay; Kenneth F. Whyte; Martin Allen; Robert C. Tam; Caroline J. Dore; Michael Henley; P. Mary Cotes; Neil J. Douglas

Clin Sci (Lond) (1993) 84 (3): 319–324.

Abstract

View Articletitled, Nocturnal desaturation and serum erythropoietin: A study in patients with chronic obstructive pulmonary disease and in normal subjects

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Effects of correcting arterial hypoxaemia on respiratory resistance in patients with chronic obstructive pulmonary disease

C. I. Coe; N. B. Pride

Clin Sci (Lond) (1993) 84 (3): 325–329.

Abstract

View Articletitled, Effects of correcting arterial hypoxaemia on respiratory resistance in patients with chronic obstructive pulmonary disease

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Normal values for handgrip strength in 920 men and women aged over 65 years, and longitudinal changes over 4 years in 620 survivors

E. J. Bassey; U. J. Harries

Clin Sci (Lond) (1993) 84 (3): 331–337.

Abstract

View Articletitled, Normal values for handgrip strength in 920 men and women aged over 65 years, and longitudinal changes over 4 years in 620 survivors

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Electron paramagnetic resonance spectroscopy of stable free radicals in the liver compared with ultrastructural and functional damage in a rat model of alcohol- and iron-overload

Graham P. Butcher; Nigel Deighton; Roger M. Batt; Boliang Ding; Susan Haywood; John Hoffman; Malcolm J. Jackson; Martyn C. R. Symons; Jonathan M. Rhodes

Clin Sci (Lond) (1993) 84 (3): 339–348.

Abstract

View Articletitled, Electron paramagnetic resonance spectroscopy of stable free radicals in the liver compared with ultrastructural and functional damage in a rat model of alcohol- and iron-overload

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Altered glomerular steady-state levels of tumour necrosis factor-α mRNA during nephrotic and sclerotic phases of puromycin aminonucleoside nephrosis in rats

Tsukasa Nakamura; Isao Ebihara; Mitsumine Fukui; Toshimasa Takahashi; Yasuhiko Tomino; Hikaru Koide

Clin Sci (Lond) (1993) 84 (3): 349–356.

Abstract

View Articletitled, Altered glomerular steady-state levels of tumour necrosis factor-<em>α</em> mRNA during nephrotic and sclerotic phases of puromycin aminonucleoside nephrosis in rats

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Oncogenic plasmid DNA and liver injury agent dictates liver cancer development in a mouse model

Candesartan restores blood–brain barrier dysfunction, mitigates aberrant gene expression, and extends lifespan in a knockin mouse model of epileptogenesis

REV-ERBα agonist SR10067 attenuates Th2 cytokine-mediated barrier dysfunction in human bronchial epithelial cells

PDCD10 promotes the tumour-supporting functions of TGF-β in pancreatic cancer

Endothelin-1 down-regulates nuclear factor erythroid 2-related factor-2 and contributes to perivascular adipose tissue dysfunction in obesity

Editorial Review

Tumour necrosis factor-α: Its role in the metabolic response to sepsis

GLAXO/MRS Young Investigator Medal

Genetics of a multifactorial disease: Autoimmune type I diabetes mellitus

Papers

Cardiovascular responses to a high-fat and a high-carbohydrate meal in healthy elderly subjects

Paradoxical forearm vasodilatation and haemodynamic improvement during cardiopulmonary baroreceptor unloading in patients with congestive heart failure

Chronic insulin treatment in rats: Evidence against a role for insulin as a pressor agent

Free-radical scavengers, thiol-containing reagents and endothelium-dependent relaxation in isolated rat and human resistance arteries

Lack of effect of peripheral nervous blockade on nocturnal fluctuations in lower-leg subcutaneous blood flow in man

Cerebrospinal fluid levels of substance P and calcitonin-gene-related peptide: Correlation with sural nerve levels and neuropathic signs in sensory diabetic polyneuropathy

Possible long-lasting inhibition of converting enzyme by enalapril in human cerebrospinal fluid

Nocturnal desaturation and serum erythropoietin: A study in patients with chronic obstructive pulmonary disease and in normal subjects

Effects of correcting arterial hypoxaemia on respiratory resistance in patients with chronic obstructive pulmonary disease

Normal values for handgrip strength in 920 men and women aged over 65 years, and longitudinal changes over 4 years in 620 survivors

Electron paramagnetic resonance spectroscopy of stable free radicals in the liver compared with ultrastructural and functional damage in a rat model of alcohol- and iron-overload

Altered glomerular steady-state levels of tumour necrosis factor-α mRNA during nephrotic and sclerotic phases of puromycin aminonucleoside nephrosis in rats

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