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Articles

A Method for the Continuous Measurement and Display of Pulmonary Resistance in Man

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R. Lane, S. Freedman, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1993) 84 (6): 671–673.
https://doi.org/10.1042/cs0840671
Published: 01 June 1993
View articletitled, A Method for the Continuous Measurement and Display of Pulmonary Resistance in Man
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Articles

Wakefulness Drive to Breathe Evinced by Assisting Inspiration with Airway Pressure

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MJ Morrell, SA Shea, A Guz
Journal: Clinical Science
Clin Sci (Lond) (1992) 83 (s27): 21P.
https://doi.org/10.1042/cs083021P
Published: 01 July 1992
View articletitled, Wakefulness Drive to Breathe Evinced by Assisting Inspiration with Airway Pressure
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Articles

Ventilatory Response to Exercise in Man Increases by Prior Conditioning of Breathing with Added Dead Space

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S H Moosavi, L Adams, A Guz
Journal: Clinical Science
Clin Sci (Lond) (1992) 82 (s26): 32P–33P.
https://doi.org/10.1042/cs082032Pb
Published: 01 March 1992
View articletitled, Ventilatory Response to Exercise in Man Increases by Prior Conditioning of Breathing with Added Dead Space
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Articles

A Method for the Continuous Measurement of Pulmonary Resistance

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R Lane, S Freedman, A Guz
Journal: Clinical Science
Clin Sci (Lond) (1992) 82 (s26): 31P.
https://doi.org/10.1042/cs082031P
Published: 01 March 1992
View articletitled, A Method for the Continuous Measurement of Pulmonary Resistance
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Articles

Isolation and Partial Characterisation of Sheep Bronchial Inhibitor of Elastase from Bronchoalveolar Lavage

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R Mistry, PD Snashall, A Guz, TD Tetley
Journal: Clinical Science
Clin Sci (Lond) (1991) 80 (s24): 21P.
https://doi.org/10.1042/cs080021Pa
Published: 01 March 1991
View articletitled, Isolation and Partial Characterisation of Sheep Bronchial Inhibitor of Elastase from Bronchoalveolar Lavage
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Articles

Negative Pharyngeal Pressure Causes Reflex Upper Airway Dilator Muscle Activation in Man

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JA Innes, RL Horner, A Guz
Journal: Clinical Science
Clin Sci (Lond) (1990) 78 (s22): 16P.
https://doi.org/10.1042/cs078016Pb
Published: 01 January 1990
View articletitled, Negative Pharyngeal Pressure Causes Reflex Upper Airway Dilator Muscle Activation in Man
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Articles

Do Human Alveolar Type II Cells Proliferate “In Vitro”?

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L Bingle, TB Bull, B Fox, A Guz, RJ Richards, TD Tetley
Journal: Clinical Science
Clin Sci (Lond) (1990) 78 (s22): 3P–4P.
https://doi.org/10.1042/cs078003Pc
Published: 01 January 1990
View articletitled, Do Human Alveolar Type II Cells Proliferate “In Vitro”?
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Articles

A Possible Anti-Inflammatory Mechanism for Glucocorticoids in the Human Lung

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SF Smith, NJ Goulding, TD Tetley, JL Godolphin, A Guz, RJ Flower
Journal: Clinical Science
Clin Sci (Lond) (1989) 77 (s21): 20P.
https://doi.org/10.1042/cs077020P
Published: 01 December 1989
View articletitled, A Possible Anti-Inflammatory Mechanism for Glucocorticoids in the Human Lung
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Articles

Is there Clinically-Useful Information in Patients' Descriptions of Their Respiratory Discomfort?

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M Elliott, L Adams, K Murphy, A Cockcroft, A Guz
Journal: Clinical Science
Clin Sci (Lond) (1989) 76 (s20): 35P.
https://doi.org/10.1042/cs076035Pa
Published: 01 January 1989
View articletitled, Is there Clinically-Useful Information in Patients' Descriptions of Their Respiratory Discomfort?
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Articles

Intermittent Measurements of FEV 1 are not Adequate to Follow Changes in Pulmonary Resistance Raised by Methacholine During Chemically-Stimulated Breathing

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R Lane, S Freedman, A Guz
Journal: Clinical Science
Clin Sci (Lond) (1988) 75 (s19): 2P.
https://doi.org/10.1042/cs075002Pb
Published: 01 December 1988
View articletitled, Intermittent Measurements of FEV 1 are not Adequate to Follow Changes in Pulmonary Resistance Raised by Methacholine During Chemically-Stimulated Breathing
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Articles

Interleukin-1 and tumour necrosis factor cause hypotension in the conscious rabbit

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J. R. Weinberg, D. J. M. Wright, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1988) 75 (3): 251–255.
https://doi.org/10.1042/cs0750251
Published: 01 September 1988
View articletitled, Interleukin-1 and tumour necrosis factor cause hypotension in the conscious rabbit
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Articles

Effect of hyperoxia and hypoxia on exercise-induced breathlessness in normal subjects

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N. Chronos, L. Adams, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1988) 74 (5): 531–537.
https://doi.org/10.1042/cs0740531
Published: 01 May 1988
View articletitled, Effect of hyperoxia and hypoxia on exercise-induced breathlessness in normal subjects
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Articles

Ventilation and breathlessness on maximal exercise in patients with interstitial lung disease after local anaesthetic aerosol inhalation

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A. J. Winning, R. D. Hamilton, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1988) 74 (3): 275–281.
https://doi.org/10.1042/cs0740275
Published: 01 March 1988
View articletitled, Ventilation and breathlessness on maximal exercise in patients with interstitial lung disease after local anaesthetic aerosol inhalation
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Articles

Demonstration of the Hering-Breuer Inflation Reflex in Man during Sleep

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A.J. Winnning, R.D. Hamilton, R.L. Horner, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1988) 74 (s18): 1P.
https://doi.org/10.1042/cs074001Pa
Published: 01 January 1988
View articletitled, Demonstration of the Hering-Breuer Inflation Reflex in Man during Sleep
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Articles

Interleukin 1 and Tumour Necrosis Factor Cause Reversible Hypotension in the Conscious Rabbit

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J Weinberg, A Guz
Journal: Clinical Science
Clin Sci (Lond) (1988) 74 (s18): 24P.
https://doi.org/10.1042/cs074024Pa
Published: 01 January 1988
View articletitled, Interleukin 1 and Tumour Necrosis Factor Cause Reversible Hypotension in the Conscious Rabbit
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Articles

Maximal Incremental Exercise after Airway Anaesthesia in Patients with Interstitial Long Disease

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A.J. Winning, R.D. Hamilton, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1988) 74 (s18): 71P.
https://doi.org/10.1042/cs074071P
Published: 01 January 1988
View articletitled, Maximal Incremental Exercise after Airway Anaesthesia in Patients with Interstitial Long Disease
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Articles

Pharyngeal Computed Tomography (CT) during Obstructive Sleep Apnoea

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RL Horner, SA Shea, E Bowden, L Chin, J Moivor, A Guz
Journal: Clinical Science
Clin Sci (Lond) (1988) 74 (s18): 28P.
https://doi.org/10.1042/cs074028Pa
Published: 01 January 1988
View articletitled, Pharyngeal Computed Tomography (CT) during Obstructive Sleep Apnoea
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Articles

Is hypercapnia necessary for the ventilatory response to exercise in man?

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K. Murphy, R. P. Stidwill, Brenda A. Cross, Kathryn D. Leaver, E. Anastassiades, M. Phillips, A. Guz, S. J. G. Semple
Journal: Clinical Science
Clin Sci (Lond) (1987) 73 (6): 617–625.
https://doi.org/10.1042/cs0730617
Published: 01 December 1987
View articletitled, Is hypercapnia necessary for the ventilatory response to exercise in man?
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Articles

Is low-level respiratory resistive loading during exercise perceived as breathlessness?

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R. Lane, L. Adams, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1987) 73 (6): 627–634.
https://doi.org/10.1042/cs0730627
Published: 01 December 1987
View articletitled, Is low-level respiratory resistive loading during exercise perceived as breathlessness?
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Articles

Systolic Time Intervals in Febrile Normotensive Patients

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JR Weinberg, JA Innes, A Guz
Journal: Clinical Science
Clin Sci (Lond) (1987) 73 (s17): 20P.
https://doi.org/10.1042/cs073020P
Published: 01 December 1987
View articletitled, Systolic Time Intervals in Febrile Normotensive Patients
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Articles

Stroke Volume and Cardiac Output in Febrile Normotensive Patients

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JR Weinberg, JA Innes, A Guz
Journal: Clinical Science
Clin Sci (Lond) (1987) 73 (s17): 20P.
https://doi.org/10.1042/cs073020Pa
Published: 01 December 1987
View articletitled, Stroke Volume and Cardiac Output in Febrile Normotensive Patients
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Articles

Ventilatory Response to Progressive Hypercapnic Stimulation Following Combined Heart-Lung Transplantation in Man

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N.R. Banner, M.H. Lloyd, R. Lane, A. Guz, M.H. Yacoub
Journal: Clinical Science
Clin Sci (Lond) (1987) 73 (s17): 6P.
https://doi.org/10.1042/cs073006Pa
Published: 01 December 1987
View articletitled, Ventilatory Response to Progressive Hypercapnic Stimulation Following Combined Heart-Lung Transplantation in Man
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Articles

Effects of Topical Corticosteroid Therapy on Immune Reactions in Human Skin

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J. Ashworth, J. Booker, S.M. Breathnach, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1987) 73 (s17): 18P.
https://doi.org/10.1042/cs073018P
Published: 01 December 1987
View articletitled, Effects of Topical Corticosteroid Therapy on Immune Reactions in Human Skin
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Articles

Voluntary isocapnic hyperventilation and breathlessness during exercise in normal subjects

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R. Lane, A. Cockcroft, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1987) 73 (5): 519–523.
https://doi.org/10.1042/cs0730519
Published: 01 November 1987
View articletitled, Voluntary isocapnic hyperventilation and breathlessness during exercise in normal subjects
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Articles

Breathlessness and respiratory mechanics during reflex or voluntary hyperventilation in patients with chronic airflow limitation

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S. Freedman, R. Lane, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1987) 73 (3): 311–318.
https://doi.org/10.1042/cs0730311
Published: 01 September 1987
View articletitled, Breathlessness and respiratory mechanics during reflex or voluntary hyperventilation in patients with chronic airflow limitation
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Articles

Arterial oxygen saturation and breathlessness in patients with chronic obstructive airways disease

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R. Lane, A. Cockcroft, L. Adams, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1987) 72 (6): 693–698.
https://doi.org/10.1042/cs0720693
Published: 01 June 1987
View articletitled, Arterial oxygen saturation and breathlessness in patients with chronic obstructive airways disease
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Articles

Elastase Profile of Human Lung Lavage

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A.D. Hersh, N.A. Roberts, A. Guz, T.D. Tetley
Journal: Clinical Science
Clin Sci (Lond) (1987) 72 (s16): 6P.
https://doi.org/10.1042/cs072006P
Published: 01 January 1987
View articletitled, Elastase Profile of Human Lung Lavage
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Articles

Abolition of Drug-Induced Bronchoconstriction by Exercise and Hyperventilation

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S Freedman, R Lane, M Gillett, A Guz
Journal: Clinical Science
Clin Sci (Lond) (1987) 72 (s16): 36P.
https://doi.org/10.1042/cs072036P
Published: 01 January 1987
View articletitled, Abolition of Drug-Induced Bronchoconstriction by Exercise and Hyperventilation
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Articles

Increased Bronchial Responsiveness to Methacholine but not Histamine in Combined Heart-Lung Transplant Recipients

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MK Gillett, R Heaton, NR Banner, MH Yacoub, A Guz
Journal: Clinical Science
Clin Sci (Lond) (1987) 72 (s16): 36P.
https://doi.org/10.1042/cs072036Pa
Published: 01 January 1987
View articletitled, Increased Bronchial Responsiveness to Methacholine but not Histamine in Combined Heart-Lung Transplant Recipients
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Articles

Increased Co 2 Sensitivity Following Airway Anaesthesia in Laryngectohised Man

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R.D. Hamilton, A.J. Winning, A. Perry, A.D. Cheesman, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1987) 72 (s16): 36P–37P.
https://doi.org/10.1042/cs072036Pb
Published: 01 January 1987
View articletitled, Increased Co 2 Sensitivity Following Airway Anaesthesia in Laryngectohised Man
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Articles

A New Model of Endotoxin-Induced Hypotension

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JR Weinberg, K Thomas, DJM Wright, A Guz
Journal: Clinical Science
Clin Sci (Lond) (1987) 72 (s16): 72P.
https://doi.org/10.1042/cs072072Pa
Published: 01 January 1987
View articletitled, A New Model of Endotoxin-Induced Hypotension
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Articles

The Effect of Voluntary Isocapnic Hyperventilation on Breathlessness during Exercise in Normals

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R. Lane, A. Cockcroft, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1987) 72 (s16): 37P.
https://doi.org/10.1042/cs072037P
Published: 01 January 1987
View articletitled, The Effect of Voluntary Isocapnic Hyperventilation on Breathlessness during Exercise in Normals
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Articles

Skin Vascular Resistance is Elevated in Febrile Patients as Compared to Heated Controls

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JR Weinberg, K Thomas, JE Tooke, A Guz
Journal: Clinical Science
Clin Sci (Lond) (1987) 72 (s16): 75P–76P.
https://doi.org/10.1042/cs072075Pb
Published: 01 January 1987
View articletitled, Skin Vascular Resistance is Elevated in Febrile Patients as Compared to Heated Controls
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Articles

Profile of Elastase Activity Released by Human Lung Lavage Cells in Culture

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S.F. Smith, A. Guz, T.D. Tetley
Journal: Clinical Science
Clin Sci (Lond) (1987) 72 (s16): 84P.
https://doi.org/10.1042/cs072084P
Published: 01 January 1987
View articletitled, Profile of Elastase Activity Released by Human Lung Lavage Cells in Culture
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Articles

Respiratory and cardiovascular effects of central and peripheral intravenous injections of capsaicin in man: Evidence for pulmonary chemosensitivity

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A. J. Winning, R. D. Hamilton, S. A. Shea, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1986) 71 (5): 519–526.
https://doi.org/10.1042/cs0710519
Published: 01 November 1986
View articletitled, Respiratory and cardiovascular effects of central and peripheral intravenous injections of capsaicin in man: Evidence for pulmonary chemosensitivity
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Articles

The measurement of breathlessness induced in normal subjects: individual differences

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L. Adams, N. Chronos, R. Lane, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1986) 70 (2): 131–140.
https://doi.org/10.1042/cs0700131
Published: 01 February 1986
View articletitled, The measurement of breathlessness induced in normal subjects: individual differences
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Articles

The effects of Local Anaesthetic Aerosol on Pulmonary Chemosensitivity in Dog and Man

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A.J. Winning, R.D. Hamilton, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1986) 71 (s15): 34P–35P.
https://doi.org/10.1042/cs071034Pb
Published: 01 January 1986
View articletitled, The effects of Local Anaesthetic Aerosol on Pulmonary Chemosensitivity in Dog and Man
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Articles

Effects of Supplementary Oxygen on Exercise Ventilation and Breathlessness in Patients with C.O.A.D

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A. Cockcroft, R. Lane, L. Adams, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1986) 70 (s13): 46P.
https://doi.org/10.1042/cs070046Pb
Published: 01 January 1986
View articletitled, Effects of Supplementary Oxygen on Exercise Ventilation and Breathlessness in Patients with C.O.A.D
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Articles

Pulsed Doppler Measurements of the Flow, Velocity and Acceleration of Aortic Blood on Exercise in Normal Subjects Aged over 45

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J.A. Innes, T.D. Simon, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1986) 70 (s13): 3P.
https://doi.org/10.1042/cs070003Pb
Published: 01 January 1986
View articletitled, Pulsed Doppler Measurements of the Flow, Velocity and Acceleration of Aortic Blood on Exercise in Normal Subjects Aged over 45
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Articles

An Animal Model of Emphysema: Biochemistry and Morphology of Normal and Elastase Treated Blotchy Mouse Lungs

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G.J. Phillips, B. Fox, A.C.E. McCartney, A. Guz, T.D. Tetley
Journal: Clinical Science
Clin Sci (Lond) (1986) 71 (s15): 81P.
https://doi.org/10.1042/cs071081P
Published: 01 January 1986
View articletitled, An Animal Model of Emphysema: Biochemistry and Morphology of Normal and Elastase Treated Blotchy Mouse Lungs
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Articles

Breathlessness during different forms of ventilatory stimulation: a study of mechanisms in normal subjects and respiratory patients

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L. Adams, R. Lane, S. A. Shea, A. Cockcroft, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1985) 69 (6): 663–672.
https://doi.org/10.1042/cs0690663
Published: 01 December 1985
View articletitled, Breathlessness during different forms of ventilatory stimulation: a study of mechanisms in normal subjects and respiratory patients
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Articles

Comparison of Extracellular Activity in Lung Lavage from Current, Ex- and Non-Smokers

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S.F. Smith, A. Guz, N.T. Cooke, G.H. Burton, T.D. Tetley
Journal: Clinical Science
Clin Sci (Lond) (1985) 69 (s12): 34P.
https://doi.org/10.1042/cs069034Pa
Published: 01 December 1985
View articletitled, Comparison of Extracellular Activity in Lung Lavage from Current, Ex- and Non-Smokers
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Articles

The Effects of Stimulating Lung Afferents in man with Intravenous Capsaicin

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A.J. Winning, R.D. Hamilton, S.A. Shea, W. Kox, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1985) 69 (s12): 34P–35P.
https://doi.org/10.1042/cs069034Pb
Published: 01 December 1985
View articletitled, The Effects of Stimulating Lung Afferents in man with Intravenous Capsaicin
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Articles

Effect of External Resistive Respiratory Muscle Loading on Exercise-Induced Breathlessness in Normals

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R. Lane, L. Adams, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1985) 69 (s12): 6P.
https://doi.org/10.1042/cs069006Pa
Published: 01 December 1985
View articletitled, Effect of External Resistive Respiratory Muscle Loading on Exercise-Induced Breathlessness in Normals
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Articles

An Investigation into the Effect of Pulmonary Surfactant on Enzymatic Degradation of Elastin In Vitro

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T.D. Tetley, C. Conte, E. Harris, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1985) 69 (s12): 6P–7P.
https://doi.org/10.1042/cs069006Pb
Published: 01 December 1985
View articletitled, An Investigation into the Effect of Pulmonary Surfactant on Enzymatic Degradation of Elastin In Vitro
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Articles

Effect of Exercise Training on Walking Distance, Exercise Ventilation and Breathlessness in Patients with Coad

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A. Cockcroft, A. Beaumont, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1985) 69 (s12): 7P.
https://doi.org/10.1042/cs069007P
Published: 01 December 1985
View articletitled, Effect of Exercise Training on Walking Distance, Exercise Ventilation and Breathlessness in Patients with Coad
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Articles

Breathlessness and Lung Mechanics during Hypercapnea and Voluntary Hyperventilation in Patients with Chronic Airflow Obstruction

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S. Freedman, R. Lane, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1985) 69 (s12): 7P.
https://doi.org/10.1042/cs069007Pa
Published: 01 December 1985
View articletitled, Breathlessness and Lung Mechanics during Hypercapnea and Voluntary Hyperventilation in Patients with Chronic Airflow Obstruction
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Articles

Urinary Desmosine Excretion: Assessment of its use as an Indicator of Pulmonary Elastolysis in αlPI-Deficiency and Chronic Lung Suppuration

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V. Pai, T.D. Tetley, G. Phillips, D.C.S. Hutchison, N.T. Cooke, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1985) 69 (s12): 58P.
https://doi.org/10.1042/cs069058P
Published: 01 December 1985
View articletitled, Urinary Desmosine Excretion: Assessment of its use as an Indicator of Pulmonary Elastolysis in αlPI-Deficiency and Chronic Lung Suppuration
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Articles

Acute Effects of Cigarette Smoking on the Antiprotease: Protease Balance of The Human Lung Surface

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T.D. Tetley, S.F. Smith, G.H. Burton, N.T. Cooke, A. Winning, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1985) 69 (s12): 58P.
https://doi.org/10.1042/cs069058Pa
Published: 01 December 1985
View articletitled, Acute Effects of Cigarette Smoking on the Antiprotease: Protease Balance of The Human Lung Surface
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Articles

The Measurement of Breathlessness Induced in Normal Subjects: Validity of two Scaling Techniques

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L. Adams, N. Chronos, R. Lane, A. Guz
Journal: Clinical Science
Clin Sci (Lond) (1985) 69 (1): 7–16.
https://doi.org/10.1042/cs0690007
Published: 01 July 1985
View articletitled, The Measurement of Breathlessness Induced in Normal Subjects: Validity of two Scaling Techniques
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