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John D. Imig
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Articles

SARS-CoV-2 spike protein causes cardiovascular disease independent of viral infection

In Collection
Coronavirus
John D. Imig
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (6): 431–434.
https://doi.org/10.1042/CS20220028
Published: 29 March 2022
View article titled, SARS-CoV-2 spike protein causes cardiovascular disease independent of viral infection
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Articles

Eicosanoid blood vessel regulation in physiological and pathological states

John D. Imig
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (20): 2707–2727.
https://doi.org/10.1042/CS20191209
Published: 23 October 2020
View article titled, Eicosanoid blood vessel regulation in physiological and pathological states
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Articles

Epoxyeicosatrienoic acid analog EET-B attenuates post-myocardial infarction remodeling in spontaneously hypertensive rats

Jan Neckář, Md. Abdul Hye Khan, Garrett J. Gross, Michaela Cyprová, Jaroslav Hrdlička, Alena Kvasilová, John R. Falck, William B. Campbell, Lenka Sedláková, Šárka Škutová, Veronika Olejníčková, Martina Gregorovičová, David Sedmera, František Kolář, John D. Imig
Journal: Clinical Science
Clin Sci (Lond) (2019) 133 (8): 939–951.
https://doi.org/10.1042/CS20180728
Published: 29 April 2019
View article titled, Epoxyeicosatrienoic acid analog EET-B attenuates post-myocardial infarction remodeling in spontaneously hypertensive rats
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Articles

Epoxyeicosatrienoic acid analogue mitigates kidney injury in a rat model of radiation nephropathy

Md. Abdul Hye Khan, Brian Fish, Geneva Wahl, Amit Sharma, John R. Falck, Mahesh P. Paudyal, John E. Moulder, John D. Imig, Eric P. Cohen
Journal: Clinical Science
Clin Sci (Lond) (2016) 130 (8): 587–599.
https://doi.org/10.1042/CS20150778
Published: 08 March 2016
View article titled, Epoxyeicosatrienoic acid analogue mitigates kidney injury in a rat model of radiation nephropathy
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Includes: Supplementary data
Articles

Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition

Md. Abdul Hye Khan, Tengis S. Pavlov, Sarah V. Christain, Jan Neckář, Alexander Staruschenko, Kathryn M. Gauthier, Jorge H. Capdevila, John R. Falck, William B. Campbell, John D. Imig
Journal: Clinical Science
Clin Sci (Lond) (2014) 127 (7): 463–474.
https://doi.org/10.1042/CS20130479
Published: 17 June 2014
View article titled, Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition
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Includes: Supplementary data
Articles

Inhibition of soluble epoxide hydrolase by cis -4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension

Jan Neckář, Libor Kopkan, Zuzana Husková, František Kolář, František Papoušek, Herbert J. Kramer, Sung Hee Hwang, Bruce D. Hammock, John D. Imig, Jiří Malý, Ivan Netuka, Bohuslav Ošťádal, Luděk Červenka
Journal: Clinical Science
Clin Sci (Lond) (2012) 122 (11): 513–527.
https://doi.org/10.1042/CS20110622
Published: 10 February 2012
View article titled, Inhibition of soluble epoxide hydrolase by cis -4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension
Open the PDF for Inhibition of soluble epoxide hydrolase by cis -4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension in another window
Includes: Supplementary data
Articles

Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertensioninduced end-organ damage in Ren-2 transgenic rats

Věra Čertíková Chábová, Agnieszka Walkowska, Elzbieta Kompanowska-Jezierska, Janusz Sadowski, Petr Kujal, Zdenka Vernerová, Zdeňa Vaňourková, Libor Kopkan, Herbert J. Kramer, John R. Falck, John D. Imig, Bruce D. Hammock, Ivana Vaněčková, Luděk Červenka
Journal: Clinical Science
Clin Sci (Lond) (2010) 118 (10): 617–632.
https://doi.org/10.1042/CS20090459
Published: 23 February 2010
View article titled, Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertensioninduced end-organ damage in Ren-2 transgenic rats
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Includes: Supplementary data
Articles

Obesity is the major contributor to vascular dysfunction and inflammation in high-fat diet hypertensive rats

Ahmed A. Elmarakby, John D. Imig
Journal: Clinical Science
Clin Sci (Lond) (2010) 118 (4): 291–301.
https://doi.org/10.1042/CS20090395
Published: 16 November 2009
View article titled, Obesity is the major contributor to vascular dysfunction and inflammation in high-fat diet hypertensive rats
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Articles

Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto–Kakizaki rats

Jeffrey J. Olearczyk, Jeffrey E. Quigley, Bradford C. Mitchell, Tatsuo Yamamoto, In-Hae Kim, John W. Newman, Ayala Luria, Bruce D. Hammock, John D. Imig
Journal: Clinical Science
Clin Sci (Lond) (2009) 116 (1): 61–70.
https://doi.org/10.1042/CS20080039
Published: 28 November 2008
View article titled, Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto–Kakizaki rats
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Articles

Eicosanoids and renal vascular function in diseases

John D. Imig
Journal: Clinical Science
Clin Sci (Lond) (2006) 111 (1): 21–34.
https://doi.org/10.1042/CS20050251
Published: 14 June 2006
View article titled, Eicosanoids and renal vascular function in diseases
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Articles

Rofecoxib decreases renal injury in obese Zucker rats

Aparajita DEY, Christine MARIC, Wayne H. KAESEMEYER, Constantine Z. ZAHARIS, Janet STEWART, Jennifer S. POLLOCK, John D. IMIG
Journal: Clinical Science
Clin Sci (Lond) (2004) 107 (6): 561–570.
https://doi.org/10.1042/CS20040125
Published: 24 November 2004
View article titled, Rofecoxib decreases renal injury in obese Zucker rats
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