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Thomas Jansson
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Articles

PiggyBac Transposase Mediated Inducible Trophoblast-specific Knockdown of Mtor Decreases Placental Nutrient Transport and Fetal Growth

Open Access
Fredrick J Rosario, Johann Urschitz, Haide Razavy, Marlee Elston, Powell L Theresa, Thomas Jansson
Journal: Clinical Science
Clin Sci (Lond) (2025) CS20243293.
https://doi.org/10.1042/CS20243293
Published: 18 June 2025
View articletitled, PiggyBac Transposase Mediated Inducible Trophoblast-specific Knockdown of Mtor Decreases Placental Nutrient Transport and Fetal Growth
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Articles

Overexpression of the LAT1 in primary human trophoblast cells increases the uptake of essential amino acids and activates mTOR signaling

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In Collection
Reproductive Physiology and Disease
Fredrick J. Rosario, Johann Urschitz, Theresa L. Powell, Thomas L. Brown, Thomas Jansson
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (21): 1651–1664.
https://doi.org/10.1042/CS20230490
Published: 10 November 2023
View articletitled, Overexpression of the LAT1 in primary human trophoblast cells increases the uptake of essential amino acids and activates mTOR signaling
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Articles

Maternal glucagon-like peptide-1 is positively associated with fetal growth in pregnancies complicated with obesity

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In Collection
Reproductive Physiology and Disease
Jerad H. Dumolt, Fredrick J. Rosario, Avery C. Kramer, Stacee Horwitz, Theresa L. Powell, Thomas Jansson
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (8): 663–678.
https://doi.org/10.1042/CS20220890
Published: 21 April 2023
View articletitled, Maternal glucagon-like peptide-1 is positively associated with fetal growth in pregnancies complicated with obesity
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Articles

A novel technique using chronic infusion of small extracellular vesicles from gestational diabetes mellitus causes glucose intolerance in pregnant mice

Open Access
In Collection
Reproductive Physiology and Disease
Laura B James-Allan, Frederick J Rosario, Lana Madi, Kelsey Barner, Soumyalekshmi Nair, Andrew Lai, Flavio Carrion, Theresa L Powell, Carlos Salomon, Thomas Jansson
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (21): 1535–1549.
https://doi.org/10.1042/CS20220484
Published: 03 November 2022
View articletitled, A novel technique using chronic infusion of small extracellular vesicles from gestational diabetes mellitus causes glucose intolerance in pregnant mice
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Includes: Supplementary data
Articles

Placenta-specific Slc38a2 /SNAT2 knockdown causes fetal growth restriction in mice

Open Access
Owen R. Vaughan, Katarzyna Maksym, Elena Silva, Kenneth Barentsen, Russel V. Anthony, Thomas L. Brown, Sara L. Hillman, Rebecca Spencer, Anna L. David, Fredrick J. Rosario, Theresa L. Powell, Thomas Jansson
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (17): 2049–2066.
https://doi.org/10.1042/CS20210575
Published: 31 August 2021
View articletitled, Placenta-specific Slc38a2 /SNAT2 knockdown causes fetal growth restriction in mice
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Includes: Supplementary data
Articles

Inhibition of mechanistic target of rapamycin signaling decreases levels of O-GlcNAc transferase and increases serotonin release in the human placenta

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Amy Catherine Kelly, Anita Kramer, Fredrick J. Rosario, Theresa L. Powell, Thomas Jansson
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (23): 3123–3136.
https://doi.org/10.1042/CS20201050
Published: 07 December 2020
View articletitled, Inhibition of mechanistic target of rapamycin signaling decreases levels of O-GlcNAc transferase and increases serotonin release in the human placenta
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Includes: Supplementary data
Articles

Placental function in maternal obesity

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Amy C. Kelly, Theresa L. Powell, Thomas Jansson
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (8): 961–984.
https://doi.org/10.1042/CS20190266
Published: 21 April 2020
View articletitled, Placental function in maternal obesity
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Articles

Down-regulation of placental Cdc42 and Rac1 links mTORC2 inhibition to decreased trophoblast amino acid transport in human intrauterine growth restriction

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Thomas Jansson, Marisol Castillo-Castrejon, Madhulika B. Gupta, Theresa L. Powell, Fredrick J. Rosario
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (1): 53–70.
https://doi.org/10.1042/CS20190794
Published: 10 January 2020
View articletitled, Down-regulation of placental Cdc42 and Rac1 links mTORC2 inhibition to decreased trophoblast amino acid transport in human intrauterine growth restriction
Open the PDF for Down-regulation of placental Cdc42 and Rac1 links mTORC2 inhibition to decreased trophoblast amino acid transport in human intrauterine growth restriction in another window
Includes: Supplementary data
Articles

Human placental exosomes in gestational diabetes mellitus carry a specific set of miRNAs associated with skeletal muscle insulin sensitivity

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Soumyalekshmi Nair, Nanthini Jayabalan, Dominic Guanzon, Carlos Palma, Katherin Scholz-Romero, Omar Elfeky, Felipe Zuñiga, Valeska Ormazabal, Emilio Diaz, Gregory E. Rice, Gregory Duncombe, Thomas Jansson, Harold David McIntyre, Martha Lappas, Carlos Salomon
Journal: Clinical Science
Clin Sci (Lond) (2018) 132 (22): 2451–2467.
https://doi.org/10.1042/CS20180487
Published: 30 November 2018
View articletitled, Human placental exosomes in gestational diabetes mellitus carry a specific set of miRNAs associated with skeletal muscle insulin sensitivity
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Includes: Supplementary data
Articles

Alterations in placental long chain polyunsaturated fatty acid metabolism in human intrauterine growth restriction

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Stephanie Skuby Chassen, Veronique Ferchaud-Roucher, Madhulika B. Gupta, Thomas Jansson, Theresa L. Powell
Journal: Clinical Science
Clin Sci (Lond) (2018) 132 (5): 595–607.
https://doi.org/10.1042/CS20171340
Published: 15 March 2018
View articletitled, Alterations in placental long chain polyunsaturated fatty acid metabolism in human intrauterine growth restriction
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Includes: Supplementary data
Articles

Regulation of amino acid transporter trafficking by mTORC1 in primary human trophoblast cells is mediated by the ubiquitin ligase Nedd4-2

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Fredrick J. Rosario, Kris Genelyn Dimasuay, Yoshikatsu Kanai, Theresa L. Powell, Thomas Jansson
Journal: Clinical Science
Clin Sci (Lond) (2016) 130 (7): 499–512.
https://doi.org/10.1042/CS20150554
Published: 17 February 2016
View articletitled, Regulation of amino acid transporter trafficking by mTORC1 in primary human trophoblast cells is mediated by the ubiquitin ligase Nedd4-2
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Includes: Supplementary data
Articles

Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR

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Yi-Yung Chen, Fredrick J. Rosario, Majida Abu Shehab, Theresa L. Powell, Madhulika B. Gupta, Thomas Jansson
Journal: Clinical Science
Clin Sci (Lond) (2015) 129 (12): 1131–1141.
https://doi.org/10.1042/CS20150511
Published: 22 October 2015
View articletitled, Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR
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Includes: Supplementary data
Articles

Role of the placenta in fetal programming: underlying mechanisms and potential interventional approaches

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Thomas Jansson, Theresa L. Powell
Journal: Clinical Science
Clin Sci (Lond) (2007) 113 (1): 1–13.
https://doi.org/10.1042/CS20060339
Published: 01 June 2007
View articletitled, Role of the placenta in fetal programming: underlying mechanisms and potential interventional approaches
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