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Articles

Identification of endoplasmic reticulum stress-associated lncRNAs influencing inflammation and VSMC function in abdominal aortic aneurysm

Rafael Almendra-Pegueros, Cristina Rodriguez, Mercedes Camacho, David Sánchez-Infantes, J. Luis Sánchez-Quesada, Susana Cáncer, Elvira Pérez-Marlasca, Gema Medina-Gómez, José Martinez-González, Ana B. García-Redondo, María Galán
Journal: Clinical Science
Clin Sci (Lond) (2025) 139 (06): 357–372.
https://doi.org/10.1042/CS20242476
Published: 25 March 2025
View articletitled, Identification of endoplasmic reticulum stress-associated lncRNAs influencing inflammation and VSMC function in abdominal aortic aneurysm
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Includes: Supplementary data
Articles

PDCD10/CCM3, a potential target for pancreatic ductal adenocarcinoma?

Hendrik Ungefroren
Journal: Clinical Science
Clin Sci (Lond) (2025) 139 (03): 281–286.
https://doi.org/10.1042/CS20241916
Published: 04 February 2025
View articletitled, PDCD10/CCM3, a potential target for pancreatic ductal adenocarcinoma?
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Articles

Sex differences in physiological response to increased neuronal excitability in a knockin mouse model of pediatric epilepsy

Michael F. Hammer, Collin T. Krzyzaniak, Erfan Bahramnejad, Kiran J. Smelser, Joshua B. Hack, Joseph C. Watkins, Patrick T. Ronaldson
Journal: Clinical Science
Clin Sci (Lond) (2024) 138 (4): 205–223.
https://doi.org/10.1042/CS20231572
Published: 21 February 2024
View articletitled, Sex differences in physiological response to increased neuronal excitability in a knockin mouse model of pediatric epilepsy
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Includes: Supplementary data
Articles

Transcriptome-based exploration of potential molecular targets and mechanisms of selenomethionine in alleviating renal ischemia–reperfusion injury

Jun Pei, Xiaomao Tian, Chengjun Yu, Jin Luo, Yifan Hong, Jie Zhang, Sheng Wen, Yi Hua, Guanghui Wei
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (18): 1477–1498.
https://doi.org/10.1042/CS20230818
Published: 22 September 2023
View articletitled, Transcriptome-based exploration of potential molecular targets and mechanisms of selenomethionine in alleviating renal ischemia–reperfusion injury
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Articles

Regulation of cholesterol homeostasis in osteoporosis mechanisms and therapeutics

Chuncha Bao, Tao Wu, Siyi Zhu, Xiaoyi Wang, Yujia Zhang, Xiangxiu Wang, Lin Yang, Chengqi He
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (15): 1131–1143.
https://doi.org/10.1042/CS20220752
Published: 09 August 2023
View articletitled, Regulation of cholesterol homeostasis in osteoporosis mechanisms and therapeutics
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Articles

CEACAM5 inhibits the lymphatic metastasis of head and neck squamous cell carcinoma by regulating epithelial–mesenchymal transition via inhibiting MDM2

Xudong Wang, Yanshi Li, Min Pan, Tao Lu, Min Wang, Zhihai Wang, Chuan Liu, Guohua Hu
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (22): 1691–1710.
https://doi.org/10.1042/CS20220581
Published: 25 November 2022
View articletitled, CEACAM5 inhibits the lymphatic metastasis of head and neck squamous cell carcinoma by regulating epithelial–mesenchymal transition via inhibiting MDM2
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Includes: Supplementary data
Articles

Dietary restriction and medical therapy drives PPARα-regulated improvements in early diabetic kidney disease in male rats

William P. Martin, Meera Nair, Yeong H.D. Chuah, Daniel Malmodin, Anders Pedersen, Sanna Abrahamsson, Michaela Hutter, Mahmoud Abdelaal, Jessie A. Elliott, Naomi Fearon, Hans Eckhardt, Catherine Godson, Eoin P. Brennan, Lars Fändriks, Carel W. le Roux, Neil G. Docherty
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (21): 1485–1511.
https://doi.org/10.1042/CS20220205
Published: 03 November 2022
View articletitled, Dietary restriction and medical therapy drives PPARα-regulated improvements in early diabetic kidney disease in male rats
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Includes: Supplementary data
Articles

Multicellular regulation of miR-196a-5p and miR-425-5 from adipose stem cell-derived exosomes and cardiac repair

Nathalia C. de Almeida Oliveira, Elida A. Neri, Caio M. Silva, Iuri C. Valadão, Miriam H. Fonseca-Alaniz, Camila Zogbi, Débora Levy, Sergio P. Bydlowski, Jose Eduardo Krieger
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (17): 1281–1301.
https://doi.org/10.1042/CS20220216
Published: 05 September 2022
View articletitled, Multicellular regulation of miR-196a-5p and miR-425-5 from adipose stem cell-derived exosomes and cardiac repair
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Includes: Supplementary data
Articles

Xbp1s-Ddit3 promotes MCT-induced pulmonary hypertension

Hongxia Jiang, Dandan Ding, Yuanzhou He, Xiaochen Li, Yongjian Xu, Xiansheng Liu
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (21): 2467–2481.
https://doi.org/10.1042/CS20210612
Published: 01 November 2021
View articletitled, Xbp1s-Ddit3 promotes MCT-induced pulmonary hypertension
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Articles

The immune niche of the liver

Michael L. Cheng, Diana Nakib, Catia T. Perciani, Sonya A. MacParland
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (20): 2445–2466.
https://doi.org/10.1042/CS20190654
Published: 28 October 2021
View articletitled, The immune niche of the liver
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Articles

Time to fiddle with your unpublished data

In Collection
Translational meta-research
Michael J. Ryan, Rhian M. Touyz
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (1): 101–103.
https://doi.org/10.1042/CS20201298
Published: 06 January 2021
View articletitled, Time to fiddle with your unpublished data
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Articles

Developmental programming of cardiovascular function: a translational perspective

Stephane L. Bourque, Sandra T. Davidge
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (22): 3023–3046.
https://doi.org/10.1042/CS20191210
Published: 24 November 2020
View articletitled, Developmental programming of cardiovascular function: a translational perspective
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Articles

miR-20a-5p is enriched in hypoxia-derived tubular exosomes and protects against acute tubular injury

Wenjuan Yu, Honghui Zeng, Junzhe Chen, Sha Fu, Qiuyan Huang, Yanchun Xu, Anping Xu, Hui-yao Lan, Ying Tang
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (16): 2223–2234.
https://doi.org/10.1042/CS20200288
Published: 28 August 2020
View articletitled, miR-20a-5p is enriched in hypoxia-derived tubular exosomes and protects against acute tubular injury
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Includes: Supplementary data
Articles

Acute myeloid leukemia immune escape by epigenetic CD48 silencing

Zhiding Wang, Yang Xiao, Wei Guan, Mengzhen Wang, Jinghong Chen, Linlin Zhang, Yan Li, Qian Xiong, Hong Wang, Maoquan Wang, Yuyan Li, Na Lv, Yonghui Li, Lixin Wang, Li Yu
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (2): 261–271.
https://doi.org/10.1042/CS20191170
Published: 29 January 2020
View articletitled, Acute myeloid leukemia immune escape by epigenetic CD48 silencing
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Includes: Supplementary data
Articles

Transcriptome sequencing of circular RNA reveals a novel circular RNA-has_circ_0114427 in the regulation of inflammation in acute kidney injury

Yiling Cao, Xuhua Mi, Dongmei Zhang, Zheng Wang, Yongdi Zuo, Wanxin Tang
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (2): 139–154.
https://doi.org/10.1042/CS20190990
Published: 23 January 2020
View articletitled, Transcriptome sequencing of circular RNA reveals a novel circular RNA-has_circ_0114427 in the regulation of inflammation in acute kidney injury
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Includes: Supplementary data
Articles

Fatty acid oxidation inhibitor etomoxir suppresses tumor progression and induces cell cycle arrest via PPARγ-mediated pathway in bladder cancer

Songtao Cheng, Gang Wang, Yejinpeng Wang, Liwei Cai, Kaiyu Qian, Lingao Ju, Xuefeng Liu, Yu Xiao, Xinghuan Wang
Journal: Clinical Science
Clin Sci (Lond) (2019) 133 (15): 1745–1758.
https://doi.org/10.1042/CS20190587
Published: 07 August 2019
View articletitled, Fatty acid oxidation inhibitor etomoxir suppresses tumor progression and induces cell cycle arrest via PPARγ-mediated pathway in bladder cancer
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Includes: Supplementary data
Articles

Down-regulation of lncRNA XIST inhibits cell proliferation via regulating miR-744/RING1 axis in non-small cell lung cancer

Jinglu Wang, Haibo Cai, Zhaoxia Dai, Gang Wang
Journal: Clinical Science
Clin Sci (Lond) (2019) 133 (14): 1567–1579.
https://doi.org/10.1042/CS20190519
Published: 18 July 2019
View articletitled, Down-regulation of lncRNA XIST inhibits cell proliferation via regulating miR-744/RING1 axis in non-small cell lung cancer
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Articles

ZEB1-AS1 is associated with poor prognosis in non-small-cell lung cancer and influences cell migration and apoptosis by repressing ID1

Jianjun Jin, Huanqin Wang, Jiming Si, Ran Ni, Yuanhua Liu, Jing Wang
Journal: Clinical Science
Clin Sci (Lond) (2019) 133 (2): 381–392.
https://doi.org/10.1042/CS20180983
Published: 30 January 2019
View articletitled, ZEB1-AS1 is associated with poor prognosis in non-small-cell lung cancer and influences cell migration and apoptosis by repressing ID1
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Articles

Color spectrographic respiratory monitoring from the external ear canal

Kamal Jafarian, Kamran Hassani, D. John Doyle, Mohammad Niakan Lahiji, Omid Moradi Moghaddam, Ala Saket, Mahsa Majidi, Farhad Izadi
Journal: Clinical Science
Clin Sci (Lond) (2018) 132 (24): 2599–2607.
https://doi.org/10.1042/CS20180748
Published: 13 December 2018
View articletitled, Color spectrographic respiratory monitoring from the external ear canal
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Articles

Imbalance of gut microbiome and intestinal epithelial barrier dysfunction in patients with high blood pressure

Seungbum Kim, Ruby Goel, Ashok Kumar, Yanfei Qi, Gil Lobaton, Koji Hosaka, Mohammed Mohammed, Eileen M. Handberg, Elaine M. Richards, Carl J. Pepine, Mohan K. Raizada
Journal: Clinical Science
Clin Sci (Lond) (2018) 132 (6): 701–718.
https://doi.org/10.1042/CS20180087
Published: 30 March 2018
View articletitled, Imbalance of gut microbiome and intestinal epithelial barrier dysfunction in patients with high blood pressure
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Includes: Supplementary data
Articles

Targeted disruption of the Kcnj5 gene in the female mouse lowers aldosterone levels

Iris Hardege, Lu Long, Raya Al Maskari, Nicola Figg, Kevin M. O’Shaughnessy
Journal: Clinical Science
Clin Sci (Lond) (2018) 132 (1): 145–156.
https://doi.org/10.1042/CS20171285
Published: 16 January 2018
View articletitled, Targeted disruption of the Kcnj5 gene in the female mouse lowers aldosterone levels
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Includes: Supplementary data
Articles

Risk of bias reporting in the recent animal focal cerebral ischaemia literature

Zsanett Bahor, Jing Liao, Malcolm R. Macleod, Alexandra Bannach-Brown, Sarah K. McCann, Kimberley E. Wever, James Thomas, Thomas Ottavi, David W. Howells, Andrew Rice, Sophia Ananiadou, Emily Sena
Journal: Clinical Science
Clin Sci (Lond) (2017) 131 (20): 2525–2532.
https://doi.org/10.1042/CS20160722
Published: 13 October 2017
View articletitled, Risk of bias reporting in the recent animal focal cerebral ischaemia literature
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