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Articles

Oncogenic plasmid DNA and liver injury agent dictates liver cancer development in a mouse model

Vincent Chiu, Christine Yee, Nathan Main, Igor Stevanovski, Matthew J Watt, Trevor Wilson, Peter Angus, Tara Roberts, Nicholas Shackel, Chandana B Chandana Herath
Journal: Clinical Science
Clin Sci (Lond) (2024) CS20240560.
https://doi.org/10.1042/CS20240560
Published: 10 September 2024
View article titled, Oncogenic plasmid DNA and liver injury agent dictates liver cancer development in a mouse model
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Articles

PDCD10 promotes the tumour-supporting functions of TGF-β in pancreatic cancer

Qianwen Zhou, Katja Breitkopf-Heinlein, Haristi Gaitantzi, Emrullah Birgin, Christoph Reissfelder, Nuh N Rahbari
Journal: Clinical Science
Clin Sci (Lond) (2024) CS20240450.
https://doi.org/10.1042/CS20240450
Published: 30 August 2024
View article titled, PDCD10 promotes the tumour-supporting functions of TGF-β in pancreatic cancer
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Articles

When the liver is in poor condition, so is the heart - cardiac remodelling in MASH mouse models

Isabelle A Leclercq, Sebastian Bott, Justine Lallement, Alice Marino, Evangelos-Panagiotis Daskalopoulos, Christophe Beauloye, Hrag Esfahani, Chantal Dessy
Journal: Clinical Science
Clin Sci (Lond) (2024) CS20240833.
https://doi.org/10.1042/CS20240833
Published: 29 August 2024
View article titled, When the liver is in poor condition, so is the heart - cardiac remodelling in MASH mouse models
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Articles

Differential changes in end organ immune cells and inflammation in salt-sensitive hypertension: effects of increasing M2 macrophages

Shobana Navaneethabalakrishnan, Bethany L. Goodlett, Hannah L. Smith, Robert A. Montalvo, II, Alyssa Cardenas, Brett M. Mitchell
Journal: Clinical Science
Clin Sci (Lond) (2024) 138 (14): 921–940.
https://doi.org/10.1042/CS20240699
Published: 16 July 2024
View article titled, Differential changes in end organ immune cells and inflammation in salt-sensitive hypertension: effects of increasing M2 macrophages
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Includes: Supplementary data
Articles

Differential changes in end organ immune cells and inflammation in salt-sensitive hypertension: effects of lowering blood pressure

Shobana Navaneethabalakrishnan, Bethany L. Goodlett, Hannah L. Smith, Alyssa Cardenas, Asia Burns, Brett M. Mitchell
Journal: Clinical Science
Clin Sci (Lond) (2024) 138 (14): 901–920.
https://doi.org/10.1042/CS20240698
Published: 16 July 2024
View article titled, Differential changes in end organ immune cells and inflammation in salt-sensitive hypertension: effects of lowering blood pressure
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Includes: Supplementary data
Articles

miR-486-5p protects against rat ischemic kidney injury and prevents the transition to chronic kidney disease and vascular dysfunction

Adrianna Douvris, Jose L. Viñas, Alexey Gutsol, Joseph Zimpelmann, Dylan Burger, Kevin D. Burns
Journal: Clinical Science
Clin Sci (Lond) (2024) 138 (10): 599–614.
https://doi.org/10.1042/CS20231752
Published: 22 May 2024
View article titled, miR-486-5p protects against rat ischemic kidney injury and prevents the transition to chronic kidney disease and vascular dysfunction
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Includes: Supplementary data
Articles

Inflammatory liver diseases and susceptibility to sepsis

Hong Lu
Journal: Clinical Science
Clin Sci (Lond) (2024) 138 (7): 435–487.
https://doi.org/10.1042/CS20230522
Published: 04 April 2024
View article titled, Inflammatory liver diseases and susceptibility to sepsis
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Articles

Therapeutic implication of human placental extract to prevent liver cirrhosis in rats with metabolic dysfunction-associated steatohepatitis

Mitsuyoshi Yamagata, Mutsumi Tsuchishima, Takashi Saito, Mikihiro Tsutsumi, Joseph George
Journal: Clinical Science
Clin Sci (Lond) (2024) 138 (5): 327–349.
https://doi.org/10.1042/CS20230533
Published: 05 March 2024
View article titled, Therapeutic implication of human placental extract to prevent liver cirrhosis in rats with metabolic dysfunction-associated steatohepatitis
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Articles

Tetramethylpyrazine attenuates renal tubular epithelial cell ferroptosis in contrast-induced nephropathy by inhibiting transferrin receptor and intracellular reactive oxygen species

Zhongqiang Zhu, Jun Li, Zhiyong Song, Tonglu Li, Zongping Li, Xuezhong Gong
Journal: Clinical Science
Clin Sci (Lond) (2024) 138 (5): 235–249.
https://doi.org/10.1042/CS20231184
Published: 27 February 2024
View article titled, Tetramethylpyrazine attenuates renal tubular epithelial cell ferroptosis in contrast-induced nephropathy by inhibiting transferrin receptor and intracellular reactive oxygen species
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Includes: Supplementary data
Articles

NaHCO 3 loading causes increased arterial pressure and kidney damage in rats with chronic kidney disease

Elinor C. Mannon, P. Robinson Muller, Jingping Sun, Weston B. Bush, Alex Coleman, Hiram Ocasio, Aaron J. Polichnowski, Michael W. Brands, Paul M. O'Connor
Journal: Clinical Science
Clin Sci (Lond) (2024) 138 (4): 189–203.
https://doi.org/10.1042/CS20231709
Published: 19 February 2024
View article titled, NaHCO 3 loading causes increased arterial pressure and kidney damage in rats with chronic kidney disease
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Articles

Physiological response to fetal intravenous lipid emulsion

In Collection
Reproductive Physiology and Disease
Brian D. Piccolo, Athena Chen, Samantha Louey, Kent L.R. Thornburg, Sonnet S. Jonker
Journal: Clinical Science
Clin Sci (Lond) (2024) 138 (3): 117–134.
https://doi.org/10.1042/CS20231419
Published: 02 February 2024
View article titled, Physiological response to fetal intravenous lipid emulsion
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Includes: Supplementary data
Articles

Importance of the gut microbiota in mice with a ‘humanized’ bile acid pool

In Collection
New discoveries in bile acids, gut microbiota and host interactions in health and diseases
Justine Gillard, Isabelle A. Leclercq
Journal: Clinical Science
Clin Sci (Lond) (2024) 138 (1): 61–64.
https://doi.org/10.1042/CS20231465
Published: 10 January 2024
View article titled, Importance of the gut microbiota in mice with a ‘humanized’ bile acid pool
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Articles

Bile salt signaling and bile salt-based therapies in cardiometabolic disease

In Collection
New discoveries in bile acids, gut microbiota and host interactions in health and diseases
Claire C.J. Groenen, Thuc-Anh Nguyen, Coen C. Paulusma, Stan F.J. van de Graaf
Journal: Clinical Science
Clin Sci (Lond) (2024) 138 (1): 1–21.
https://doi.org/10.1042/CS20230934
Published: 05 January 2024
View article titled, Bile salt signaling and bile salt-based therapies in cardiometabolic disease
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Articles

Immune landscape of the kidney allograft in response to rejection

Harsimar Kaur Ahuja, Shafquat Azim, Daniel Maluf, Valeria R. Mas
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (24): 1823–1838.
https://doi.org/10.1042/CS20230493
Published: 21 December 2023
View article titled, Immune landscape of the kidney allograft in response to rejection
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Articles

Cellular senescence and kidney aging

In Collection
The biology of ageing: Geroscience and the exposome
Nikolai Rex, Anette Melk, Roland Schmitt
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (24): 1805–1821.
https://doi.org/10.1042/CS20230140
Published: 21 December 2023
View article titled, Cellular senescence and kidney aging
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Articles

Leptin antagonism attenuates hypertension and renal injury in an experimental model of autoimmune disease

William J. Kalusche, Clinton T. Case, Erin B. Taylor
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (23): 1771–1785.
https://doi.org/10.1042/CS20230924
Published: 14 December 2023
View article titled, Leptin antagonism attenuates hypertension and renal injury in an experimental model of autoimmune disease
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Includes: Supplementary data
Articles

PE (0:0/14:0), an endogenous metabolite of the gut microbiota, exerts protective effects against sepsis-induced intestinal injury by modulating the AHR/CYP1A1 pathway

Wang Ze Tian, Qi Yue, Wang Fei, Peng Zi Yao, Rui Qin Han, Jianguo Tang
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (22): 1753–1769.
https://doi.org/10.1042/CS20230704
Published: 22 November 2023
View article titled, PE (0:0/14:0), an endogenous metabolite of the gut microbiota, exerts protective effects against sepsis-induced intestinal injury by modulating the AHR/CYP1A1 pathway
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Articles

Gut microbiota depletion aggravates bile acid-induced liver pathology in mice with a human-like bile acid composition

In Collection
New discoveries in bile acids, gut microbiota and host interactions in health and diseases
Esther Verkade, Wenqiang Shen, Milaine V. Hovingh, Niels L. Mulder, Krisztina de Bruyn, Martijn Koehorst, Hilde D. de Vries, Vincent W. Bloks, Folkert Kuipers, Jan Freark de Boer
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (21): 1637–1650.
https://doi.org/10.1042/CS20230812
Published: 10 November 2023
View article titled, Gut microbiota depletion aggravates bile acid-induced liver pathology in mice with a human-like bile acid composition
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Includes: Supplementary data
Articles

Transcriptome-based exploration of potential molecular targets and mechanisms of selenomethionine in alleviating renal ischemia–reperfusion injury

Jun Pei, Xiaomao Tian, Chengjun Yu, Jin Luo, Yifan Hong, Jie Zhang, Sheng Wen, Yi Hua, Guanghui Wei
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (18): 1477–1498.
https://doi.org/10.1042/CS20230818
Published: 22 September 2023
View article titled, Transcriptome-based exploration of potential molecular targets and mechanisms of selenomethionine in alleviating renal ischemia–reperfusion injury
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Articles

B- and T-lymphocyte attenuator could be a new player in accelerated atherosclerosis associated with chronic kidney disease

Nuria Dolade, Sandra Rayego-Mateos, Alicia Garcia-Carrasco, Maryse Guerin, Jose-Luis Martín-Ventura, Marta Ruiz-Ortega, Pierre-Louis Tharaux, Jose Manuel Valdivielso
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (17): 1409–1429.
https://doi.org/10.1042/CS20230399
Published: 13 September 2023
View article titled, B- and T-lymphocyte attenuator could be a new player in accelerated atherosclerosis associated with chronic kidney disease
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Includes: Supplementary data
Articles

Maternal hepatic adaptations during obese pregnancy encompass lobe-specific mitochondrial alterations and oxidative stress

Luís F. Grilo, João D. Martins, Mariana S. Diniz, Carolina Tocantins, Chiara H. Cavallaro, Inês Baldeiras, Teresa Cunha-Oliveira, Stephen Ford, Peter W. Nathanielsz, Paulo J. Oliveira, Susana P. Pereira
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (17): 1347–1372.
https://doi.org/10.1042/CS20230048
Published: 01 September 2023
View article titled, Maternal hepatic adaptations during obese pregnancy encompass lobe-specific mitochondrial alterations and oxidative stress
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Includes: Supplementary data
Articles

Brief early life angiotensin-converting enzyme inhibition attenuates the diuretic response to saline loading in sheep with solitary functioning kidney

Zoe McArdle, Reetu R. Singh, Karen M. Moritz, Michiel F. Schreuder, Kate M. Denton
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (16): 1285–1296.
https://doi.org/10.1042/CS20230663
Published: 22 August 2023
View article titled, Brief early life angiotensin-converting enzyme inhibition attenuates the diuretic response to saline loading in sheep with solitary functioning kidney
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Includes: Supplementary data
Articles

Decoding the role of leptin and adiponectin in obesity-related gastrointestinal cancer

Vanda Marques, Fabiola Arella, Marta B. Afonso, André A. Santos, Cecília M.P. Rodrigues
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (15): 1095–1114.
https://doi.org/10.1042/CS20230411
Published: 02 August 2023
View article titled, Decoding the role of leptin and adiponectin in obesity-related gastrointestinal cancer
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Articles

Ovarian cancer G protein-coupled receptor 1 deficiency exacerbates crystal deposition and kidney injury in oxalate nephropathy in female mice

Nima Yassini, Janine Sprenger, Eva Maria Pastor Arroyo, Christiane Krudewig, Giovanni Pellegrini, Nicole Joller, Carsten A. Wagner, Pedro Henrique Imenez Silva
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (14): 1013–1025.
https://doi.org/10.1042/CS20230421
Published: 25 July 2023
View article titled, Ovarian cancer G protein-coupled receptor 1 deficiency exacerbates crystal deposition and kidney injury in oxalate nephropathy in female mice
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Includes: Supplementary data
Articles

Absence of gut microbiota reduces neonatal survival and exacerbates liver disease in Cyp2c70 -deficient mice with a human-like bile acid composition

In Collection
New discoveries in bile acids, gut microbiota and host interactions in health and diseases
Wilhelm Sjöland, Annika Wahlström, Kassem Makki, Marc Schöler, Antonio Molinaro, Lisa Olsson, Thomas Uwe Greiner, Robert Caesar, Jan Freark de Boer, Folkert Kuipers, Fredrik Bäckhed, Hanns-Ulrich Marschall
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (13): 995–1011.
https://doi.org/10.1042/CS20230413
Published: 14 July 2023
View article titled, Absence of gut microbiota reduces neonatal survival and exacerbates liver disease in Cyp2c70 -deficient mice with a human-like bile acid composition
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Includes: Supplementary data
Articles

High sodium promotes the secretion and synthesis of PTH through PiT-1-IKKβ pathway in parathyroid gland in vitro

Aiwen Shen, Yu Wang, Guoxin Ye, Jianping Mao, Qian Zhang, Jing Chen
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (12): 947–962.
https://doi.org/10.1042/CS20220754
Published: 20 June 2023
View article titled, High sodium promotes the secretion and synthesis of PTH through PiT-1-IKKβ pathway in parathyroid gland in vitro
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Includes: Supplementary data
Articles

Restoration of the gut barrier integrity and restructuring of the gut microbiome in aging by angiotensin-(1–7)

In Collection
The biology of ageing: Geroscience and the exposome
Kishore Chittimalli, Jesmin Jahan, Anil Sakamuri, Zachary L. McAdams, Aaron C. Ericsson, Yagna P.R. Jarajapu
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (11): 913–930.
https://doi.org/10.1042/CS20220904
Published: 14 June 2023
View article titled, Restoration of the gut barrier integrity and restructuring of the gut microbiome in aging by angiotensin-(1–7)
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Includes: Supplementary data
Articles

Beneficial effects of brief early life angiotensin-converting enzyme inhibition wane with time in sheep with solitary functioning kidney

Zoe McArdle, Reetu R. Singh, Helle Bielefeldt-Ohmann, Karen M. Moritz, Kate M. Denton, Michiel F. Schreuder
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (8): 603–615.
https://doi.org/10.1042/CS20220811
Published: 19 April 2023
View article titled, Beneficial effects of brief early life angiotensin-converting enzyme inhibition wane with time in sheep with solitary functioning kidney
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Articles

Potential therapeutic action of tauroursodeoxycholic acid against cholestatic liver injury via hepatic Fxr/Nrf2 and CHOP-DR5-caspase-8 pathway

In Collection
New discoveries in bile acids, gut microbiota and host interactions in health and diseases
Guochao Song, Fengyi Weng, Bin Zou, Jing Zhao, Jingyi Jin, Dongming Yan, Kai Huang, Xin Sun, Chenghai Liu, Yiyang Hu, Yue Li, Furong Qiu
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (7): 561–577.
https://doi.org/10.1042/CS20220674
Published: 13 April 2023
View article titled, Potential therapeutic action of tauroursodeoxycholic acid against cholestatic liver injury via hepatic Fxr/Nrf2 and CHOP-DR5-caspase-8 pathway
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Includes: Supplementary data
Articles

Skin-specific mechanisms of body fluid regulation in hypertension

Jun Yu Chen, Khai Syuen Chew, Sheon Mary, Philipp Boder, Domenico Bagordo, Gian Paolo Rossi, Rhian M. Touyz, Christian Delles, Giacomo Rossitto
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (3): 239–250.
https://doi.org/10.1042/CS20220609
Published: 07 February 2023
View article titled, Skin-specific mechanisms of body fluid regulation in hypertension
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Includes: Supplementary data
Articles

Overexpression of notch signaling in renin cells leads to a polycystic kidney phenotype

Brian C. Belyea, Fang Xu, Margaret Wiltsie, Hayes Fountain, Jennifer Charlton, Agnes B. Fogo, Maria Luisa Soledad Sequeira-Lopez, Roberto Ariel Gomez
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (1): 35–45.
https://doi.org/10.1042/CS20220496
Published: 05 January 2023
View article titled, Overexpression of notch signaling in renin cells leads to a polycystic kidney phenotype
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Includes: Supplementary data
Articles

Biological tuners to reshape the bile acid pool for therapeutic purposes in non-alcoholic fatty liver disease

In Collection
New discoveries in bile acids, gut microbiota and host interactions in health and diseases
Justine Gillard, Isabelle A. Leclercq
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (1): 65–85.
https://doi.org/10.1042/CS20220697
Published: 05 January 2023
View article titled, Biological tuners to reshape the bile acid pool for therapeutic purposes in non-alcoholic fatty liver disease
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Articles

Inhibition of monoamine oxidase B reduces atherosclerosis and fatty liver in mice

Shu-Huei Wang, Feng-Chiao Tsai, Heng-Huei Lin, Tse-Ya Yu, Chun-Heng Kuo, Hung-Yuan Li, Mao-Shin Lin
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (1): 17–30.
https://doi.org/10.1042/CS20220477
Published: 03 January 2023
View article titled, Inhibition of monoamine oxidase B reduces atherosclerosis and fatty liver in mice
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Articles

The fatty acid imbalance of cystic fibrosis exists at birth independent of feeding in pig and ferret models

Aliye Uc, Birgitta Strandvik, Jianrong Yao, Xiaoming Liu, Yaling Yi, Xingshen Sun, Ruth Welti, John F. Engelhardt, Andrew W. Norris
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (24): 1773–1791.
https://doi.org/10.1042/CS20220450
Published: 13 December 2022
View article titled, The fatty acid imbalance of cystic fibrosis exists at birth independent of feeding in pig and ferret models
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Includes: Supplementary data
Articles

The nonindustrialised microbiome in a modern world

Fergus Shanahan, Tarini S. Ghosh, Michael G. Molloy, Paul W. O’Toole
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (22): 1683–1690.
https://doi.org/10.1042/CS20220203
Published: 23 November 2022
View article titled, The nonindustrialised microbiome in a modern world
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Articles

α-Adrenergic blockade prevented environmental temperature reduction-induced transient portal pressure surge in cirrhotic and portal hypertensive rats

Hui-Chun Huang, Ching-Chih Chang, Chon Kit Pun, Ming-Hung Tsai, Chiao-Lin Chuang, Shao-Jung Hsu, Yi-Hsiang Huang, Ming-Chih Hou, Fa-Yauh Lee
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (20): 1449–1466.
https://doi.org/10.1042/CS20220290
Published: 26 October 2022
View article titled, α-Adrenergic blockade prevented environmental temperature reduction-induced transient portal pressure surge in cirrhotic and portal hypertensive rats
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Includes: Supplementary data
Articles

Small-molecule Wnt inhibitors are a potential novel therapy for intestinal fibrosis in Crohns disease

Amy Lewis, Saray Sánchez, Giulio Berti, Belen Pan-Castillo, Anke Nijhuis, Shameer Mehta, Liliane Eleid, Hannah Gordon, Radha Gadhok, Christopher Kimberley, Annamaria Minicozzi, Joanne Chin-Aleong, Roger Feakins, Robert Kypta, James Oliver Lindsay, Andrew Silver
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (19): 1405–1423.
https://doi.org/10.1042/CS20210889
Published: 14 October 2022
View article titled, Small-molecule Wnt inhibitors are a potential novel therapy for intestinal fibrosis in Crohns disease
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Includes: Supplementary data
Articles

Hypertension and renal disease programming: focus on the early postnatal period

Maria Florencia Albertoni Borghese, Lucas Humberto Oronel, Maria Del Carmen Ortiz, Mónica Patricia Majowicz
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (17): 1303–1339.
https://doi.org/10.1042/CS20220293
Published: 08 September 2022
View article titled, Hypertension and renal disease programming: focus on the early postnatal period
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Articles

Interactions between the intrarenal dopaminergic and the renin–angiotensin systems in the control of systemic arterial pressure

Pedro Alves Soares Vaz de Castro, Pedro A. Jose, Ana Cristina Simões e Silva
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (16): 1205–1227.
https://doi.org/10.1042/CS20220338
Published: 18 August 2022
View article titled, Interactions between the intrarenal dopaminergic and the renin–angiotensin systems in the control of systemic arterial pressure
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Articles

Modulating hepatic macrophages with annexin A1 in non-alcoholic steatohepatitis

Federico F. De Ponti, Charlotte L. Scott
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (15): 1111–1115.
https://doi.org/10.1042/CS20220258
Published: 01 August 2022
View article titled, Modulating hepatic macrophages with annexin A1 in non-alcoholic steatohepatitis
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Articles

Differential effects of cyclo-oxygenase 1 and 2 inhibition on angiogenesis inhibitor-induced hypertension and kidney damage

In Collection
Cardiovascular-Oncology
Katrina M. Mirabito Colafella, Daan C.H. van Dorst, Rugina I. Neuman, Leni van Doorn, Karla Bianca Neves, Augusto C. Montezano, Ingrid M. Garrelds, Richard van Veghel, René de Vries, Estrellita Uijl, Marian C. Clahsen-van Groningen, Hans J. Baelde, Anton H. van den Meiracker, Rhian M. Touyz, Willy Visser, A.H. Jan Danser, Jorie Versmissen
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (9): 675–694.
https://doi.org/10.1042/CS20220182
Published: 10 May 2022
View article titled, Differential effects of cyclo-oxygenase 1 and 2 inhibition on angiogenesis inhibitor-induced hypertension and kidney damage
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Includes: Supplementary data
Articles

ANGPTL1 attenuates cancer migration, invasion, and stemness through regulating FOXO3a-mediated SOX2 expression in colorectal cancer

Ting-Yu Chang, Kuo-Cheng Lan, Chen-Yuan Chiu, Meei-Ling Sheu, Shing-Hwa Liu
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (9): 657–673.
https://doi.org/10.1042/CS20220043
Published: 06 May 2022
View article titled, ANGPTL1 attenuates cancer migration, invasion, and stemness through regulating FOXO3a-mediated SOX2 expression in colorectal cancer
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Includes: Supplementary data
Articles

Alkali therapy protects renal function, suppresses inflammation, and improves cellular metabolism in kidney disease

Eva Maria Pastor Arroyo, Nima Yassini, Elif Sakiri, Giancarlo Russo, Soline Bourgeois, Nilufar Mohebbi, Kerstin Amann, Nicole Joller, Carsten A. Wagner, Pedro Henrique Imenez Silva
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (8): 557–577.
https://doi.org/10.1042/CS20220095
Published: 21 April 2022
View article titled, Alkali therapy protects renal function, suppresses inflammation, and improves cellular metabolism in kidney disease
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Includes: Supplementary data
Articles

Microbiota transplantation in portal hypertension: promises and pitfalls

Emilie K. Mitten, György Baffy
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (6): 425–429.
https://doi.org/10.1042/CS20220029
Published: 25 March 2022
View article titled, Microbiota transplantation in portal hypertension: promises and pitfalls
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Articles

MicroRNAs as messengers of liver diseases: has the message finally been decrypted?

Carlos J. Pirola, Silvia Sookoian
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (5): 323–328.
https://doi.org/10.1042/CS20211177
Published: 02 March 2022
View article titled, MicroRNAs as messengers of liver diseases: has the message finally been decrypted?
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Articles

The HDAC2/SP1/miR-205 feedback loop contributes to tubular epithelial cell extracellular matrix production in diabetic kidney disease

Zongji Zheng, Shuting Zhang, Jiaqi Chen, Meina Zou, Yanlin Yang, Wen Lu, Shijing Ren, Xiangyu Wang, Wenhui Dong, Zikun Zhang, Ling Wang, Meiping Guan, Gladys L.Y. Cheing, Yaoming Xue, Yijie Jia
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (3): 223–238.
https://doi.org/10.1042/CS20210470
Published: 07 February 2022
View article titled, The HDAC2/SP1/miR-205 feedback loop contributes to tubular epithelial cell extracellular matrix production in diabetic kidney disease
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Includes: Supplementary data
Articles

AIM2 inflammasome contributes to aldosterone-induced renal injury via endoplasmic reticulum stress

Yong Wu, Huan Yang, Sujuan Xu, Ming Cheng, Jie Gu, Weichen Zhang, Shaojun Liu, Minmin Zhang
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (1): 103–120.
https://doi.org/10.1042/CS20211075
Published: 07 January 2022
View article titled, AIM2 inflammasome contributes to aldosterone-induced renal injury via endoplasmic reticulum stress
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Includes: Supplementary data
Articles

Inhibition of HDAC3 protects against kidney cold storage/transplantation injury and allograft dysfunction

Xiaohong Xiang, Guie Dong, Jiefu Zhu, Gang Zhang, Zheng Dong
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (1): 45–60.
https://doi.org/10.1042/CS20210823
Published: 05 January 2022
View article titled, Inhibition of HDAC3 protects against kidney cold storage/transplantation injury and allograft dysfunction
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Includes: Supplementary data
Articles

Salt loading decreases urinary excretion and increases intracellular accumulation of uromodulin in stroke-prone spontaneously hypertensive rats

Sheon Mary, Philipp Boder, Giacomo Rossitto, Lesley Graham, Kayley Scott, Arun Flynn, David Kipgen, Delyth Graham, Christian Delles
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (24): 2749–2761.
https://doi.org/10.1042/CS20211017
Published: 17 December 2021
View article titled, Salt loading decreases urinary excretion and increases intracellular accumulation of uromodulin in stroke-prone spontaneously hypertensive rats
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Includes: Supplementary data
Articles

The acute pressure natriuresis response is suppressed by selective ET A receptor blockade

Geoffrey Culshaw, David Binnie, Neeraj Dhaun, Patrick Hadoke, Matthew Bailey, David J Webb
Journal: Clinical Science
Clin Sci (Lond) (2021) CS20210937.
https://doi.org/10.1042/CS20210937
Published: 17 December 2021
View article titled, The acute pressure natriuresis response is suppressed by selective ET A receptor blockade
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