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Articles

Complex regulation of tau phosphorylation by the endothelin system in brain microvascular endothelial cells (BMVECs): link to barrier function

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In Collection
Endothelin XVIII Conference Collection
Eda Karakaya, Yasir Abdul, Jazlyn Edwards, Sarah Jamil, Onder Albayram, Adviye Ergul
Journal: Clinical Science
Clin Sci (Lond) (2024) 138 (21): 1329–1341.
https://doi.org/10.1042/CS20240616
Published: 24 October 2024
View articletitled, Complex regulation of tau phosphorylation by the endothelin system in brain microvascular endothelial cells (BMVECs): link to barrier function
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Includes: Supplementary data
Articles

Methylglyoxal and glyoxalase 1—a metabolic stress pathway-linking hyperglycemia to the unfolded protein response and vascular complications of diabetes

Open Access
Naila Rabbani
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (11): 819–824.
https://doi.org/10.1042/CS20220099
Published: 30 May 2022
View articletitled, Methylglyoxal and glyoxalase 1—a metabolic stress pathway-linking hyperglycemia to the unfolded protein response and vascular complications of diabetes
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Articles

Promyelocytic leukemia protein: an atherosclerosis suppressor protein?

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Cali B. Corbett, Amanda K. St. Paul, Michael V. Autieri
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (13): 1557–1561.
https://doi.org/10.1042/CS20210314
Published: 30 June 2021
View articletitled, Promyelocytic leukemia protein: an atherosclerosis suppressor protein?
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Articles

Targeting protein phosphatase PP2A for cancer therapy: development of allosteric pharmaceutical agents

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David L. Brautigan, Caroline Farrington, Goutham Narla
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (13): 1545–1556.
https://doi.org/10.1042/CS20201367
Published: 30 June 2021
View articletitled, Targeting protein phosphatase PP2A for cancer therapy: development of allosteric pharmaceutical agents
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Articles

SIRT7 restricts HBV transcription and replication through catalyzing desuccinylation of histone H3 associated with cccDNA minichromosome

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Hai-Bo Yu, Sheng-Tao Cheng, Fang Ren, Yong Chen, Xiao-Feng Shi, Vincent Kam Wai Wong, Betty Yuen Kwan Law, Ji-Hua Ren, Shan Zhong, Wei-Xian Chen, Hong-Mei Xu, Zhen-Zhen Zhang, Jie-Li Hu, Xue-Fei Cai, Yuan Hu, Wen-Lu Zhang, Quan-Xin Long, Lin He, Zhong-Wen Hu, Hui Jiang, Hong-Zhong Zhou, Ai-Long Huang, Juan Chen
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (12): 1505–1522.
https://doi.org/10.1042/CS20210392
Published: 23 June 2021
View articletitled, SIRT7 restricts HBV transcription and replication through catalyzing desuccinylation of histone H3 associated with cccDNA minichromosome
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Includes: Supplementary data
Articles

Promyelocytic leukemia protein promotes the phenotypic switch of smooth muscle cells in atherosclerotic plaques of human coronary arteries

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Weronika Karle, Samuel Becker, Philipp Stenzel, Christoph Knosalla, Günter Siegel, Oliver Baum, Andreas Zakrzewicz, Janine Berkholz
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (7): 887–905.
https://doi.org/10.1042/CS20201399
Published: 09 April 2021
View articletitled, Promyelocytic leukemia protein promotes the phenotypic switch of smooth muscle cells in atherosclerotic plaques of human coronary arteries
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Includes: Supplementary data
Articles

Inhibition of SENP2-mediated Akt deSUMOylation promotes cardiac regeneration via activating Akt pathway

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Yijin Chen, Tong Xu, Mengsha Li, Chuling Li, Yusheng Ma, Guojun Chen, Yili Sun, Hao Zheng, Guangkai Wu, Wangjun Liao, Yulin Liao, Yanmei Chen, Jianping Bin
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (6): 811–828.
https://doi.org/10.1042/CS20201408
Published: 23 March 2021
View articletitled, Inhibition of SENP2-mediated Akt deSUMOylation promotes cardiac regeneration via activating Akt pathway
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Includes: Supplementary data
Articles

The role of protein arginine methyltransferases in kidney diseases

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Chunyun Zhang, Shougang Zhuang
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (15): 2037–2051.
https://doi.org/10.1042/CS20200680
Published: 07 August 2020
View articletitled, The role of protein arginine methyltransferases in kidney diseases
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Articles

Circular RNA circFGD4 suppresses gastric cancer progression via modulating miR-532-3p/APC/β-catenin signalling pathway

Open Access
Xinglong Dai, Jianjun Liu, Xiong Guo, Anqi Cheng, Xiaoya Deng, Liqun Guo, Ziwei Wang
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (13): 1821–1839.
https://doi.org/10.1042/CS20191043
Published: 17 July 2020
View articletitled, Circular RNA circFGD4 suppresses gastric cancer progression via modulating miR-532-3p/APC/β-catenin signalling pathway
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Articles

Short-chain fatty acid, acylation and cardiovascular diseases

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In Collection
Adipose biology, cardiovascular and cardiometabolic disease
Xiao-Feng Chen, Xiangqi Chen, Xiaoqiang Tang
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (6): 657–676.
https://doi.org/10.1042/CS20200128
Published: 27 March 2020
View articletitled, Short-chain fatty acid, acylation and cardiovascular diseases
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Articles

Down-regulation of placental Cdc42 and Rac1 links mTORC2 inhibition to decreased trophoblast amino acid transport in human intrauterine growth restriction

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Thomas Jansson, Marisol Castillo-Castrejon, Madhulika B. Gupta, Theresa L. Powell, Fredrick J. Rosario
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (1): 53–70.
https://doi.org/10.1042/CS20190794
Published: 10 January 2020
View articletitled, Down-regulation of placental Cdc42 and Rac1 links mTORC2 inhibition to decreased trophoblast amino acid transport in human intrauterine growth restriction
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Includes: Supplementary data
Articles

Involvement of serum amyloid A1 in the rupture of fetal membranes through induction of collagen I degradation

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Wang-sheng Wang, Wen-jiao Li, Ya-wei Wang, Lu-yao Wang, Ya-bing Mi, Jiang-wen Lu, Yi Lu, Chu-yue Zhang, Kang Sun
Journal: Clinical Science
Clin Sci (Lond) (2019) 133 (3): 515–530.
https://doi.org/10.1042/CS20180950
Published: 12 February 2019
View articletitled, Involvement of serum amyloid A1 in the rupture of fetal membranes through induction of collagen I degradation
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Includes: Supplementary data
Articles

Implications of plasma thiol redox in disease

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Percíllia V.S. Oliveira, Francisco R.M. Laurindo
Journal: Clinical Science
Clin Sci (Lond) (2018) 132 (12): 1257–1280.
https://doi.org/10.1042/CS20180157
Published: 29 June 2018
View articletitled, Implications of plasma thiol redox in disease
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Articles

O-Linked β- N -acetylglucosamine (O-GlcNAc) modification: a new pathway to decode pathogenesis of diabetic retinopathy

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Zafer Gurel, Nader Sheibani
Journal: Clinical Science
Clin Sci (Lond) (2018) 132 (2): 185–198.
https://doi.org/10.1042/CS20171454
Published: 19 January 2018
View articletitled, O-Linked β- N -acetylglucosamine (O-GlcNAc) modification: a new pathway to decode pathogenesis of diabetic retinopathy
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Articles

Sulphur dioxide suppresses inflammatory response by sulphenylating NF-κB p65 at Cys 38 in a rat model of acute lung injury

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Siyao Chen, Yaqian Huang, Zhiwei Liu, Wen Yu, Heng Zhang, Kun Li, Xiaoqi Yu, Chaoshu Tang, Bin Zhao, Junbao Du, Hongfang Jin
Journal: Clinical Science
Clin Sci (Lond) (2017) 131 (21): 2655–2670.
https://doi.org/10.1042/CS20170274
Published: 27 October 2017
View articletitled, Sulphur dioxide suppresses inflammatory response by sulphenylating NF-κB p65 at Cys 38 in a rat model of acute lung injury
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Articles

Pharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR −/− mouse model of atherosclerosis

Open Access
Dawn Thompson, Nicola Morrice, Louise Grant, Samantha Le Sommer, Emma K. Lees, Nimesh Mody, Heather M. Wilson, Mirela Delibegovic
Journal: Clinical Science
Clin Sci (Lond) (2017) 131 (20): 2489–2501.
https://doi.org/10.1042/CS20171066
Published: 29 September 2017
View articletitled, Pharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR −/− mouse model of atherosclerosis
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Includes: Supplementary data
Articles

Urinary glycated uromodulin in diabetic kidney disease

Open Access
Chia-Chu Chang, Chen-Yu Chen, Ching-Hui Huang, Chia-Lin Wu, Hung-Ming Wu, Ping-Fang Chiu, Chew-Teng Kor, Ting-Huan Chen, Geen-Dong Chang, Cheng-Chin Kuo, Hui-Chin Wen, Chih-Yang Huang, Chung-Ho Chang
Journal: Clinical Science
Clin Sci (Lond) (2017) 131 (15): 1815–1829.
https://doi.org/10.1042/CS20160978
Published: 05 July 2017
View articletitled, Urinary glycated uromodulin in diabetic kidney disease
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Articles

Intact initiation of autophagy and mitochondrial fission by acute exercise in skeletal muscle of patients with Type 2 diabetes

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Rikke Kruse, Andreas J.T. Pedersen, Jonas M. Kristensen, Stine J. Petersson, Jørgen F.P. Wojtaszewski, Kurt Højlund
Journal: Clinical Science
Clin Sci (Lond) (2017) 131 (1): 37–47.
https://doi.org/10.1042/CS20160736
Published: 09 December 2016
View articletitled, Intact initiation of autophagy and mitochondrial fission by acute exercise in skeletal muscle of patients with Type 2 diabetes
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Includes: Supplementary data
Articles

N -glycans of growth factor receptors: their role in receptor function and disease implications

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Motoko Takahashi, Yoshihiro Hasegawa, Congxiao Gao, Yoshio Kuroki, Naoyuki Taniguchi
Journal: Clinical Science
Clin Sci (Lond) (2016) 130 (20): 1781–1792.
https://doi.org/10.1042/CS20160273
Published: 09 September 2016
View articletitled, N -glycans of growth factor receptors: their role in receptor function and disease implications
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Articles

Protein kinase C mechanisms that contribute to cardiac remodelling

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Alexandra C. Newton, Corina E. Antal, Susan F. Steinberg
Journal: Clinical Science
Clin Sci (Lond) (2016) 130 (17): 1499–1510.
https://doi.org/10.1042/CS20160036
Published: 18 July 2016
View articletitled, Protein kinase C mechanisms that contribute to cardiac remodelling
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