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Articles

Antiviral activities of hemp cannabinoids

Richard B. van Breemen, Daniel Simchuk
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (8): 633–643.
https://doi.org/10.1042/CS20220193
Published: 21 April 2023
View article titled, Antiviral activities of hemp cannabinoids
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Articles

TNF/iNOS/NO pathway mediates host susceptibility to endothelial-dependent circulatory failure and death induced by betacoronavirus infection

Ildernandes Vieira-Alves, Antonielle Rodrigues Pereira Alves, Natália Muradas Valério Souza, Tales Leonardo de Melo, Leda Maria de Castro Coimbra Campos, Larisse de Souza Barbosa Lacerda, Celso Martins Queiroz-Junior, Ana Cláudia dos Santos Pereira Andrade, Luciola Silva Barcelos, Mauro Martins Teixeira, Vivian Vasconcelos Costa, Steyner F. Cortes, Virginia S. Lemos
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (7): 543–559.
https://doi.org/10.1042/CS20220663
Published: 13 April 2023
View article titled, TNF/iNOS/NO pathway mediates host susceptibility to endothelial-dependent circulatory failure and death induced by betacoronavirus infection
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Includes: Supplementary data
Articles

Therapeutic use of calpeptin in COVID-19 infection

In Collection
Coronavirus
Jameel Inal, Ainura Paizuldaeva, Esmeralda Terziu
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (20): 1439–1447.
https://doi.org/10.1042/CS20220638
Published: 21 October 2022
View article titled, Therapeutic use of calpeptin in COVID-19 infection
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Articles

Casting a wide NET: an update on uncontrolled NETosis in response to COVID-19 infection

Erin B. Taylor
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (13): 1047–1052.
https://doi.org/10.1042/CS20220039
Published: 06 July 2022
View article titled, Casting a wide NET: an update on uncontrolled NETosis in response to COVID-19 infection
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Articles

SIRT7 restricts HBV transcription and replication through catalyzing desuccinylation of histone H3 associated with cccDNA minichromosome

Hai-Bo Yu, Sheng-Tao Cheng, Fang Ren, Yong Chen, Xiao-Feng Shi, Vincent Kam Wai Wong, Betty Yuen Kwan Law, Ji-Hua Ren, Shan Zhong, Wei-Xian Chen, Hong-Mei Xu, Zhen-Zhen Zhang, Jie-Li Hu, Xue-Fei Cai, Yuan Hu, Wen-Lu Zhang, Quan-Xin Long, Lin He, Zhong-Wen Hu, Hui Jiang, Hong-Zhong Zhou, Ai-Long Huang, Juan Chen
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (12): 1505–1522.
https://doi.org/10.1042/CS20210392
Published: 23 June 2021
View article titled, SIRT7 restricts HBV transcription and replication through catalyzing desuccinylation of histone H3 associated with cccDNA minichromosome
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Includes: Supplementary data
Articles

Adeno-associated viral (AAV) vector-mediated therapeutics for diabetic cardiomyopathy – current and future perspectives

Darnel Prakoso, Mitchel Tate, Miles J. De Blasio, Rebecca H. Ritchie
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (11): 1369–1387.
https://doi.org/10.1042/CS20210052
Published: 02 June 2021
View article titled, Adeno-associated viral (AAV) vector-mediated therapeutics for diabetic cardiomyopathy – current and future perspectives
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Articles

Host cell glutamine metabolism as a potential antiviral target

Sandro Massao Hirabara, Renata Gorjao, Adriana Cristina Levada-Pires, Laureane Nunes Masi, Elaine Hatanaka, Maria Fernanda Cury-Boaventura, Eliane Borges da Silva, Laiane Cristina dos Santos-Oliveira, Vinicius Leonardo Sousa Diniz, Tamires Afonso Duarte Serdan, Vivian Araujo Barbosa de Oliveira, Diego Ribeiro de Souza, Raquel Bragante Gritte, Talita Souza-Siqueira, Raquel Freitas Zambonatto, Tania Cristina Pithon-Curi, Roberto Barbosa Bazotte, Philip Newsholme, Rui Curi
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (2): 305–325.
https://doi.org/10.1042/CS20201042
Published: 22 January 2021
View article titled, Host cell glutamine metabolism as a potential antiviral target
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Articles

ACE2: from protection of liver disease to propagation of COVID-19

In Collection
ACE2, a multifunctional protein – from cardiovascular regulation to COVID-19
Fiona J. Warner, Harinda Rajapaksha, Nicholas Shackel, Chandana B. Herath
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (23): 3137–3158.
https://doi.org/10.1042/CS20201268
Published: 07 December 2020
View article titled, ACE2: from protection of liver disease to propagation of COVID-19
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Articles

LncRNA HOTAIR modulates hepatitis B virus transcription and replication by enhancing SP1 transcription factor

Fang Ren, Ji-Hua Ren, Chun-Li Song, Ming Tan, Hai-Bo Yu, Yu-Jiao Zhou, Yi-Ping Qin, Sheng-Tao Cheng, Yuan Zhang, Ai-Long Huang, Juan Chen, Xiao Yang
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (22): 3007–3022.
https://doi.org/10.1042/CS20200970
Published: 23 November 2020
View article titled, LncRNA HOTAIR modulates hepatitis B virus transcription and replication by enhancing SP1 transcription factor
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Includes: Supplementary data
Articles

Twenty years of progress in angiotensin converting enzyme 2 and its link to SARS-CoV-2 disease

In Collection
ACE2, a multifunctional protein – from cardiovascular regulation to COVID-19
Carlos M. Ferrario, Sarfaraz Ahmad, Leanne Groban
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (19): 2645–2664.
https://doi.org/10.1042/CS20200901
Published: 16 October 2020
View article titled, Twenty years of progress in angiotensin converting enzyme 2 and its link to SARS-CoV-2 disease
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Articles

Unpuzzling COVID-19: tissue-related signaling pathways associated with SARS-CoV-2 infection and transmission

In Collection
Coronavirus
Daniella S. Battagello, Guilherme Dragunas, Marianne O. Klein, Ana L.P. Ayub, Fernando J. Velloso, Ricardo G. Correa
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (16): 2137–2160.
https://doi.org/10.1042/CS20200904
Published: 21 August 2020
View article titled, Unpuzzling COVID-19: tissue-related signaling pathways associated with SARS-CoV-2 infection and transmission
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Articles

Impaired insulin exocytosis in chronic hepatitis C infection: contributory role of p38δ MAPK–protein kinase D–golgi complex axis

Parimala Narne
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (12): 1449–1456.
https://doi.org/10.1042/CS20200686
Published: 18 June 2020
View article titled, Impaired insulin exocytosis in chronic hepatitis C infection: contributory role of p38δ MAPK–protein kinase D–golgi complex axis
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Articles

SARS-CoV2 may evade innate immune response, causing uncontrolled neutrophil extracellular traps formation and multi-organ failure

In Collection
Coronavirus
Alain R. Thierry, Benoit Roch
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (12): 1295–1300.
https://doi.org/10.1042/CS20200531
Published: 16 June 2020
View article titled, SARS-CoV2 may evade innate immune response, causing uncontrolled neutrophil extracellular traps formation and multi-organ failure
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Articles

Covid-19: the renin–angiotensin system imbalance hypothesis

In Collection
Coronavirus
Katharina Lanza, Lucas G. Perez, Larissa B. Costa, Thiago M. Cordeiro, Vitria A. Palmeira, Victor T. Ribeiro, Ana Cristina Simões e Silva
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (11): 1259–1264.
https://doi.org/10.1042/CS20200492
Published: 08 June 2020
View article titled, Covid-19: the renin–angiotensin system imbalance hypothesis
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Articles

Soluble angiotensin-converting enzyme 2: a potential approach for coronavirus infection therapy?

In Collection
Coronavirus
Daniel Batlle, Jan Wysocki, Karla Satchell
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (5): 543–545.
https://doi.org/10.1042/CS20200163
Published: 13 March 2020
View article titled, Soluble angiotensin-converting enzyme 2: a potential approach for coronavirus infection therapy?
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Articles

CD8 + CD28 − T cells: key cytotoxic players impacting disease pathogenesis in chronic HBV infection

Madhuparna Nandi, Sourina Pal, Sumantra Ghosh, Bidhan Chandra Chakraborty, Debangana Dey, Ayana Baidya, Achintya Shil, Saran Chattopadhyaya, Soma Banerjee, Amal Santra, Abhijit Chowdhury, Simanti Datta
Journal: Clinical Science
Clin Sci (Lond) (2019) 133 (17): 1917–1934.
https://doi.org/10.1042/CS20190369
Published: 13 September 2019
View article titled, CD8 + CD28 − T cells: key cytotoxic players impacting disease pathogenesis in chronic HBV infection
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Articles

Rhinovirus-induces progression of lung disease in a mouse model of COPD via IL-33/ST2 signaling axis

Joao A. Gimenes, Jr, Vikram Srivastava, Hymavathi ReddyVari, Sudhir Kotnala, Rahul Mishra, Mohamed Farazuddin, Wuyan Li, Umadevi S. Sajjan
Journal: Clinical Science
Clin Sci (Lond) (2019) 133 (8): 983–996.
https://doi.org/10.1042/CS20181088
Published: 29 April 2019
View article titled, Rhinovirus-induces progression of lung disease in a mouse model of COPD via IL-33/ST2 signaling axis
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Includes: Supplementary data
Articles

Use of the immunoglobulin G avidity assay to differentiate between recent Zika and past dengue virus infections

Andrea K.M. Furuya, Danielle Hunt, Kirsten St. George, Alan P. Dupuis, II, Laura D. Kramer, Pei-Yong Shi, Susan Wong
Journal: Clinical Science
Clin Sci (Lond) (2019) 133 (7): 859–867.
https://doi.org/10.1042/CS20180874
Published: 04 April 2019
View article titled, Use of the immunoglobulin G avidity assay to differentiate between recent Zika and past dengue virus infections
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Includes: Supplementary data
Articles

Occurrence and regression of BK polyomavirus associated carcinoma: a clinical and next-generation sequencing study

Fangxiang Fu, Wenfeng Deng, Siyuan Yu, Yanna Liu, Lixin Yu, Rumin Liu, Jiping Lang, Dianxiang Geng, Jian Geng, Jiangtao Li, Gang Huang, Minhua Luo, Fu Xiong, Chin-Lee Wu, Yun Miao
Journal: Clinical Science
Clin Sci (Lond) (2018) 132 (16): 1753–1763.
https://doi.org/10.1042/CS20180443
Published: 30 August 2018
View article titled, Occurrence and regression of BK polyomavirus associated carcinoma: a clinical and next-generation sequencing study
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Includes: Supplementary data
Articles

The human papillomavirus replication cycle, and its links to cancer progression: a comprehensive review

Sheila V. Graham
Journal: Clinical Science
Clin Sci (Lond) (2017) 131 (17): 2201–2221.
https://doi.org/10.1042/CS20160786
Published: 10 August 2017
View article titled, The human papillomavirus replication cycle, and its links to cancer progression: a comprehensive review
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Articles

Role of human metapneumovirus and respiratory syncytial virus in asthma exacerbations: where are we now?

Penny A. Rudd, Belinda J. Thomas, Ali Zaid, Martin MacDonald, Keiko Kan-o, Michael S. Rolph, Anand R. Soorneedi, Philip G. Bardin, Suresh Mahalingam
Journal: Clinical Science
Clin Sci (Lond) (2017) 131 (14): 1713–1721.
https://doi.org/10.1042/CS20160011
Published: 30 June 2017
View article titled, Role of human metapneumovirus and respiratory syncytial virus in asthma exacerbations: where are we now?
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Articles

Pulmonary immunity to viruses

In Collection
Coronavirus
S. Rameeza Allie, Troy D. Randall
Journal: Clinical Science
Clin Sci (Lond) (2017) 131 (14): 1737–1762.
https://doi.org/10.1042/CS20160259
Published: 30 June 2017
View article titled, Pulmonary immunity to viruses
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Articles

Enhanced protective responses to a serotype-independent pneumococcal vaccine when combined with an inactivated influenza vaccine

Rachelle Babb, Austen Chen, Abiodun D. Ogunniyi, Timothy R. Hirst, Ervin E. Kara, Shaun R. McColl, Mohammed Alsharifi, James C. Paton
Journal: Clinical Science
Clin Sci (Lond) (2017) 131 (2): 169–180.
https://doi.org/10.1042/CS20160475
Published: 23 December 2016
View article titled, Enhanced protective responses to a serotype-independent pneumococcal vaccine when combined with an inactivated influenza vaccine
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