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Articles

Antiviral activities of hemp cannabinoids

Open Access
Richard B. van Breemen, Daniel Simchuk
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (8): 633–643.
https://doi.org/10.1042/CS20220193
Published: 21 April 2023
View articletitled, Antiviral activities of hemp cannabinoids
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Articles

TNF/iNOS/NO pathway mediates host susceptibility to endothelial-dependent circulatory failure and death induced by betacoronavirus infection

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Ildernandes Vieira-Alves, Antonielle Rodrigues Pereira Alves, Natália Muradas Valério Souza, Tales Leonardo de Melo, Leda Maria de Castro Coimbra Campos, Larisse de Souza Barbosa Lacerda, Celso Martins Queiroz-Junior, Ana Cláudia dos Santos Pereira Andrade, Luciola Silva Barcelos, Mauro Martins Teixeira, Vivian Vasconcelos Costa, Steyner F. Cortes, Virginia S. Lemos
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (7): 543–559.
https://doi.org/10.1042/CS20220663
Published: 13 April 2023
View articletitled, TNF/iNOS/NO pathway mediates host susceptibility to endothelial-dependent circulatory failure and death induced by betacoronavirus infection
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Includes: Supplementary data
Articles

Therapeutic use of calpeptin in COVID-19 infection

Open Access
In Collection
Coronavirus
Jameel Inal, Ainura Paizuldaeva, Esmeralda Terziu
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (20): 1439–1447.
https://doi.org/10.1042/CS20220638
Published: 21 October 2022
View articletitled, Therapeutic use of calpeptin in COVID-19 infection
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Articles

Casting a wide NET: an update on uncontrolled NETosis in response to COVID-19 infection

Open Access
Erin B. Taylor
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (13): 1047–1052.
https://doi.org/10.1042/CS20220039
Published: 06 July 2022
View articletitled, Casting a wide NET: an update on uncontrolled NETosis in response to COVID-19 infection
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Articles

SIRT7 restricts HBV transcription and replication through catalyzing desuccinylation of histone H3 associated with cccDNA minichromosome

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Hai-Bo Yu, Sheng-Tao Cheng, Fang Ren, Yong Chen, Xiao-Feng Shi, Vincent Kam Wai Wong, Betty Yuen Kwan Law, Ji-Hua Ren, Shan Zhong, Wei-Xian Chen, Hong-Mei Xu, Zhen-Zhen Zhang, Jie-Li Hu, Xue-Fei Cai, Yuan Hu, Wen-Lu Zhang, Quan-Xin Long, Lin He, Zhong-Wen Hu, Hui Jiang, Hong-Zhong Zhou, Ai-Long Huang, Juan Chen
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (12): 1505–1522.
https://doi.org/10.1042/CS20210392
Published: 23 June 2021
View articletitled, SIRT7 restricts HBV transcription and replication through catalyzing desuccinylation of histone H3 associated with cccDNA minichromosome
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Includes: Supplementary data
Articles

Adeno-associated viral (AAV) vector-mediated therapeutics for diabetic cardiomyopathy – current and future perspectives

Open Access
Darnel Prakoso, Mitchel Tate, Miles J. De Blasio, Rebecca H. Ritchie
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (11): 1369–1387.
https://doi.org/10.1042/CS20210052
Published: 02 June 2021
View articletitled, Adeno-associated viral (AAV) vector-mediated therapeutics for diabetic cardiomyopathy – current and future perspectives
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Articles

Host cell glutamine metabolism as a potential antiviral target

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Sandro Massao Hirabara, Renata Gorjao, Adriana Cristina Levada-Pires, Laureane Nunes Masi, Elaine Hatanaka, Maria Fernanda Cury-Boaventura, Eliane Borges da Silva, Laiane Cristina dos Santos-Oliveira, Vinicius Leonardo Sousa Diniz, Tamires Afonso Duarte Serdan, Vivian Araujo Barbosa de Oliveira, Diego Ribeiro de Souza, Raquel Bragante Gritte, Talita Souza-Siqueira, Raquel Freitas Zambonatto, Tania Cristina Pithon-Curi, Roberto Barbosa Bazotte, Philip Newsholme, Rui Curi
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (2): 305–325.
https://doi.org/10.1042/CS20201042
Published: 22 January 2021
View articletitled, Host cell glutamine metabolism as a potential antiviral target
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Articles

ACE2: from protection of liver disease to propagation of COVID-19

Open Access
In Collection
ACE2, a multifunctional protein – from cardiovascular regulation to COVID-19
Fiona J. Warner, Harinda Rajapaksha, Nicholas Shackel, Chandana B. Herath
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (23): 3137–3158.
https://doi.org/10.1042/CS20201268
Published: 07 December 2020
View articletitled, ACE2: from protection of liver disease to propagation of COVID-19
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Articles

LncRNA HOTAIR modulates hepatitis B virus transcription and replication by enhancing SP1 transcription factor

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Fang Ren, Ji-Hua Ren, Chun-Li Song, Ming Tan, Hai-Bo Yu, Yu-Jiao Zhou, Yi-Ping Qin, Sheng-Tao Cheng, Yuan Zhang, Ai-Long Huang, Juan Chen, Xiao Yang
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (22): 3007–3022.
https://doi.org/10.1042/CS20200970
Published: 23 November 2020
View articletitled, LncRNA HOTAIR modulates hepatitis B virus transcription and replication by enhancing SP1 transcription factor
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Includes: Supplementary data
Articles

Twenty years of progress in angiotensin converting enzyme 2 and its link to SARS-CoV-2 disease

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In Collection
ACE2, a multifunctional protein – from cardiovascular regulation to COVID-19
Carlos M. Ferrario, Sarfaraz Ahmad, Leanne Groban
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (19): 2645–2664.
https://doi.org/10.1042/CS20200901
Published: 16 October 2020
View articletitled, Twenty years of progress in angiotensin converting enzyme 2 and its link to SARS-CoV-2 disease
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Articles

Unpuzzling COVID-19: tissue-related signaling pathways associated with SARS-CoV-2 infection and transmission

Open Access
In Collection
Coronavirus
Daniella S. Battagello, Guilherme Dragunas, Marianne O. Klein, Ana L.P. Ayub, Fernando J. Velloso, Ricardo G. Correa
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (16): 2137–2160.
https://doi.org/10.1042/CS20200904
Published: 21 August 2020
View articletitled, Unpuzzling COVID-19: tissue-related signaling pathways associated with SARS-CoV-2 infection and transmission
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Articles

Impaired insulin exocytosis in chronic hepatitis C infection: contributory role of p38δ MAPK–protein kinase D–golgi complex axis

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Parimala Narne
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (12): 1449–1456.
https://doi.org/10.1042/CS20200686
Published: 18 June 2020
View articletitled, Impaired insulin exocytosis in chronic hepatitis C infection: contributory role of p38δ MAPK–protein kinase D–golgi complex axis
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Articles

SARS-CoV2 may evade innate immune response, causing uncontrolled neutrophil extracellular traps formation and multi-organ failure

Open Access
In Collection
Coronavirus
Alain R. Thierry, Benoit Roch
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (12): 1295–1300.
https://doi.org/10.1042/CS20200531
Published: 16 June 2020
View articletitled, SARS-CoV2 may evade innate immune response, causing uncontrolled neutrophil extracellular traps formation and multi-organ failure
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Articles

Covid-19: the renin–angiotensin system imbalance hypothesis

Open Access
In Collection
Coronavirus
Katharina Lanza, Lucas G. Perez, Larissa B. Costa, Thiago M. Cordeiro, Vitria A. Palmeira, Victor T. Ribeiro, Ana Cristina Simões e Silva
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (11): 1259–1264.
https://doi.org/10.1042/CS20200492
Published: 08 June 2020
View articletitled, Covid-19: the renin–angiotensin system imbalance hypothesis
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Articles

Soluble angiotensin-converting enzyme 2: a potential approach for coronavirus infection therapy?

Open Access
In Collection
Coronavirus
Daniel Batlle, Jan Wysocki, Karla Satchell
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (5): 543–545.
https://doi.org/10.1042/CS20200163
Published: 13 March 2020
View articletitled, Soluble angiotensin-converting enzyme 2: a potential approach for coronavirus infection therapy?
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Articles

CD8 + CD28 − T cells: key cytotoxic players impacting disease pathogenesis in chronic HBV infection

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Madhuparna Nandi, Sourina Pal, Sumantra Ghosh, Bidhan Chandra Chakraborty, Debangana Dey, Ayana Baidya, Achintya Shil, Saran Chattopadhyaya, Soma Banerjee, Amal Santra, Abhijit Chowdhury, Simanti Datta
Journal: Clinical Science
Clin Sci (Lond) (2019) 133 (17): 1917–1934.
https://doi.org/10.1042/CS20190369
Published: 13 September 2019
View articletitled, CD8 + CD28 − T cells: key cytotoxic players impacting disease pathogenesis in chronic HBV infection
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Articles

Rhinovirus-induces progression of lung disease in a mouse model of COPD via IL-33/ST2 signaling axis

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Joao A. Gimenes, Jr, Vikram Srivastava, Hymavathi ReddyVari, Sudhir Kotnala, Rahul Mishra, Mohamed Farazuddin, Wuyan Li, Umadevi S. Sajjan
Journal: Clinical Science
Clin Sci (Lond) (2019) 133 (8): 983–996.
https://doi.org/10.1042/CS20181088
Published: 29 April 2019
View articletitled, Rhinovirus-induces progression of lung disease in a mouse model of COPD via IL-33/ST2 signaling axis
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Includes: Supplementary data
Articles

Use of the immunoglobulin G avidity assay to differentiate between recent Zika and past dengue virus infections

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Andrea K.M. Furuya, Danielle Hunt, Kirsten St. George, Alan P. Dupuis, II, Laura D. Kramer, Pei-Yong Shi, Susan Wong
Journal: Clinical Science
Clin Sci (Lond) (2019) 133 (7): 859–867.
https://doi.org/10.1042/CS20180874
Published: 04 April 2019
View articletitled, Use of the immunoglobulin G avidity assay to differentiate between recent Zika and past dengue virus infections
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Includes: Supplementary data
Articles

Occurrence and regression of BK polyomavirus associated carcinoma: a clinical and next-generation sequencing study

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Fangxiang Fu, Wenfeng Deng, Siyuan Yu, Yanna Liu, Lixin Yu, Rumin Liu, Jiping Lang, Dianxiang Geng, Jian Geng, Jiangtao Li, Gang Huang, Minhua Luo, Fu Xiong, Chin-Lee Wu, Yun Miao
Journal: Clinical Science
Clin Sci (Lond) (2018) 132 (16): 1753–1763.
https://doi.org/10.1042/CS20180443
Published: 30 August 2018
View articletitled, Occurrence and regression of BK polyomavirus associated carcinoma: a clinical and next-generation sequencing study
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Includes: Supplementary data
Articles

The human papillomavirus replication cycle, and its links to cancer progression: a comprehensive review

Open Access
Sheila V. Graham
Journal: Clinical Science
Clin Sci (Lond) (2017) 131 (17): 2201–2221.
https://doi.org/10.1042/CS20160786
Published: 10 August 2017
View articletitled, The human papillomavirus replication cycle, and its links to cancer progression: a comprehensive review
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Articles

Role of human metapneumovirus and respiratory syncytial virus in asthma exacerbations: where are we now?

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Penny A. Rudd, Belinda J. Thomas, Ali Zaid, Martin MacDonald, Keiko Kan-o, Michael S. Rolph, Anand R. Soorneedi, Philip G. Bardin, Suresh Mahalingam
Journal: Clinical Science
Clin Sci (Lond) (2017) 131 (14): 1713–1721.
https://doi.org/10.1042/CS20160011
Published: 30 June 2017
View articletitled, Role of human metapneumovirus and respiratory syncytial virus in asthma exacerbations: where are we now?
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Articles

Pulmonary immunity to viruses

Available to Purchase
In Collection
Coronavirus
S. Rameeza Allie, Troy D. Randall
Journal: Clinical Science
Clin Sci (Lond) (2017) 131 (14): 1737–1762.
https://doi.org/10.1042/CS20160259
Published: 30 June 2017
View articletitled, Pulmonary immunity to viruses
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Articles

Enhanced protective responses to a serotype-independent pneumococcal vaccine when combined with an inactivated influenza vaccine

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Rachelle Babb, Austen Chen, Abiodun D. Ogunniyi, Timothy R. Hirst, Ervin E. Kara, Shaun R. McColl, Mohammed Alsharifi, James C. Paton
Journal: Clinical Science
Clin Sci (Lond) (2017) 131 (2): 169–180.
https://doi.org/10.1042/CS20160475
Published: 23 December 2016
View articletitled, Enhanced protective responses to a serotype-independent pneumococcal vaccine when combined with an inactivated influenza vaccine
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