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Keywords: β-adrenoreceptor
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Articles
Clin Sci (Lond) (1981) 60 (1): 33–40.
Published: 01 January 1981
...K. L. Evemy; P. Cummins; W. A. Littler 1. The effect of prolonged administration of β-adrenoreceptor-blocking agents was studied in growing rabbits. Equivalent doses of propranolol and timolol were given parenterally for 8 weeks. 2. Animals given propranolol had a significantly lower heart rate...
Articles
Clin Sci (Lond) (1979) 57 (3): 241–247.
Published: 01 September 1979
...R. D. S. Watson; T. J. Stallard; W. A. Littler 1. Sensitivity of the sino-aortic baroreflex was investigated before and after acute (23 patients) and chronic (23 patients) β-adrenoreceptor antagonism in patients with essential hypertension. 2. Sensitivity was inversely related to age ( r = −0·60...
Articles
Clin Sci (Lond) (1979) 56 (2): 115–120.
Published: 01 February 1979
... stimulated release of active renin is associated with removal of inactive renin from the circulation by the kidney. This may in fact be due to intrarenal transformation of circulating inactive renin into its active counterpart. The findings suggest that a β-adrenoreceptor might be involved in this activation...
Articles
Clin Sci Mol Med (1978) 54 (1): 17–23.
Published: 01 January 1978
... associated with frusemide diuresis. 4. Blockade of β-adrenoreceptors with propranolol, by contrast, reduced blood AII increments associated with all three procedures. 5. It is suggested that renin release during moderate haemorrhage and acute suprarenal aortic stenosis is, in the dog, partly due to...
Articles
Clin Sci Mol Med (1976) 51 (s3): 537s–540s.
Published: 01 December 1976
... in group 2 before treatment. Thus, in this latter subgroup, low-renin profiles might reflect reduced β-adrenoreceptor activity. 5. Plasma aldosterone was lower in group 2 but appeared to be inappropriately high relative to renin. 6. The data suggest that in hypertensive patients classified according...
Articles
Clin Sci Mol Med (1976) 51 (s3): 501s–563s.
Published: 01 December 1976
...D. Pugsley; B. Armstrong; M. Nassim; L. J. Beilin 1. Labetalol (AH 5158) is a new drug which has both α- and β-adrenoreceptor antagonist activity. Labetalol has been compared with propranolol and placebo for the treatment of mild to moderate hypertension (150/100 to 189/114 mmHg), in a double-blind...
Articles
Clin Sci Mol Med (1976) 51 (s3): 97s–99s.
Published: 01 December 1976
... their action on β-adrenoreceptors. 7. The system of superfusion of isolated glomeruli provides a technique for studying the influence of mediators leading to renin release acting directly on juxtaglomerular cells, independent of pressure change, tubular sodium, the sympathetic nervous system and...