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Keywords: β-cell function
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Articles

VMP1-related autophagy induced by a fructose-rich diet in β-cells: its prevention by incretins

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Bárbara Maiztegui, Verónica Boggio, Carolina L. Román, Luis E. Flores, Héctor Del Zotto, Alejandro Ropolo, Daniel Grasso, María I. Vaccaro, Juan J. Gagliardino
Journal: Clinical Science
Clin Sci (Lond) (2017) 131 (8): 673–687.
https://doi.org/10.1042/CS20170010
Published: 28 March 2017
... model assessment (HOMA) for insulin resistance (HOMA-IR) and β-cell function (HOMA-β) indices. A significant reduction in β-cell mass was associated with an increased apoptotic rate and morphological/ultrastructural changes indicative of autophagic activity. All these changes were prevented by either...
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Articles

β -Cell Function in Hypopituitary Adults before and during Growth Hormone Treatment

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Salem A. Beshyah, Susan V. Gelding, Christine Andres, Desmond G. Johnston, I. Peter Gray
Journal: Clinical Science
Clin Sci (Lond) (1995) 89 (3): 321–328.
https://doi.org/10.1042/cs0890321
Published: 01 September 1995
...Salem A. Beshyah; Susan V. Gelding; Christine Andres; Desmond G. Johnston; I. Peter Gray 1. We studied β-cell function in 40 hypopituitary adults and in 36 matched control subjects. Hypopituitary patients were studied again at 1, 3 and 6 months during a double-blind placebo-controlled trial...
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