... © 1989 The Biochemical Society and the Medical Research Society 1989 calcium metabolism disorder 1,25-dihydroxycholecalciferol glomerular filtration rate 25-hydroxycholecalciferol hyperparathyroidism Clinical Science (1989) 76, 81-86 Determinants of the serum concentration of 1,25...

... 1986 The Biochemical Society and the Medical Research Society 1986 27 1 1986 11 2 1986 calcidiol lactone 1,25-dihydroxycholecalciferol 24,25-dihydroxycholecalciferol 25,26-dihydroxycholecalciferol renal failure vitamin D metabolism-extrarenal synthesis of metabolites...

... calcaemia calcium clearance 1,25-dihydroxycholecalciferol kidney phosphataemia phosphate renal transport secondary hyperparathyroidism Clinical Science (1982) 62,503-508 503 Decrease in the tubular reabsorption of calcium with evidence for compensatory hyperparathyroidism in X-linked...

...S. E. Papapoulos; T. L. Clemens; L. M. Sandler; L. J. Fraher; J. Winer; J. L. H. O'riordan 1. 1,25-Dihydroxycholecalciferol [1,25-(OH) 2 -D 3 ] was administered orally to four normal subjects and six patients with chronic renal failure not on dialysis. The serum concentration of 1,25-(OH) 2 D 3...

..., 1,25-dihydroxycholecalciferol (1,25-(OH),D Sequential measurements of radioactive serum 25-hydroxycholecalciferol (25-(OH)D 24,254- hydroxycholecalciferol (24,25-(OH),D,) and 25,26-dihydroxycholecalciferol (25,26-(OH),D,) as well as 1,25-(OH),D3 were made for up to 10 days after injecting the labelled...

... that in phosphorus deprivation, unlike in calcium deprivation, a diet very low in phosphorus is required to stimulate the renal 25-(OH)D 3 -1-hydroxylase activity. 17 6 1977 24 10 1977 © 1978 The Biochemical Society and the Medical Research Society 1978 1,25-dihydroxycholecalciferol...

... instead of into the normal metabolite 1,25-dihydroxycholecalciferol. 2. This inhibition of the renal 1-hydroxylase disappeared on withdrawal of the diphosphonate. 3. Kidneys from chicks given diphosphonate for 12 days converted 25-hydroxycholecalciferol into 24,25-dihydroxycholecalciferol on incubation...

... and in patients with primary disorders of parathyroid function. 2. The formation of labelled 1,25-dihydroxycholecalciferol [1,25-(OH) 2 D 3 ] and labelled 24,25-dihydroxycholecalciferol [24,25-(OH) 2 D 3 ] has been related to the prevailing concentrations in serum of 25-hydroxycholecalciferol [25-(OH)D 3...

...R. G. G. Russell; R. Smith; C. Preston; R. J. Walton; C. G. Woods; R. G. Henderson; A. W. Norman 1. 1,25-Dihydroxycholecalciferol (1,25-(OH) 2 -D 3 ) was given at a dose of 5.0 nmol (2.1 μg) daily by mouth for 4–12 days to three patients with hypophosphataemic (type I), vitamin D-resistant rickets...

... of EHDP enhances the intestinal accumulation of a vitamin D 3 metabolite with the chromatographic characteristics of 1,25-dihydroxycholecalciferol. 8 11 1974 © 1975 The Biochemical Society and the Medical Research Society 1975 disodium ethane-1-hydroxy-1,1-diphosphonate calcium...

...R. G. Larkins; S. J. MacAuley; A. Rapoport; T. J. Martin; B. R. Tulloch; P. G. H. Byfield; E. W. Matthews; I. MacIntyre 1. The production of 1,25-dihydroxycholecalciferol (1,25-DHCC) from tritiated 25-hydroxycholecalciferol (25-HCC) was assessed in renal tubules prepared from vitamin D-deficient...

... with the diphosphonate, and irrespective of the duration of such treatment, responded initially to a single intravenous dose of cholecalciferol with a normal production of 1,25-dihydroxycholecalciferol. 3. This normal response was followed within 2 days by an apparent inhibition of the renal biosynthesis of 1,25...