...Helmut Witzgall; Reinhard Lorenz; Klaus Von Werder; Peter C. Weber 1. Plasma aldosterone, 18-hydroxycorticosterone (18-OH-B), 18-hydroxydeoxycorticosterone (18-OH-DOC), corticosterone, cortisol and prolactin levels were determined during an angiotensin II infusion at increasing rates both...

...James R. Sowers; Victor I. Martin; Frances W. J. Beck 1. The effects of dietary sodium intake on plasma 18-hydroxycorticosterone (18-OHB) responses to physiological stimuli and recumbent 24-h-plasma 18-OHB levels have been examined in nine normal male subjects. 2. Basal supine levels of 18-OHB...

... < 0.02). Heart rate did not change. Plasma renin activity (PRA) increased ( P < 0.002), and plasma and urinary aldosterone as well as plasma 18-hydroxycorticosterone (18- OH-B) decreased after captopril ( P < 0.02). Prostaglandin (PG) E 2 , kallikrein, urine volume, sodium and potassium excretion...

... was reduced at 30 and 60 min after captopril ( P < 0.02). Heart rate did not change during the whole experiment. Although plasma renin activity (PRA) increased ( P < 0.002), plasma and urinary aldosterone and plasma 18-hydroxycorticosterone (18-OH-B) decreased after captopril ( P < 0.02...

...G. Huston; V. I. Martin; E. A. S. Al-Dujaili; C. R. W. Edwards 1. The mineralocorticoid activity of 18-hydroxycorticosterone (18-OH-B) has been compared with that of aldosterone by using human bioassay in vivo with measurement of rectal potential difference and urinary log 10 Na + /K + ratio. 2...

... major aldosterone precursor 18-hydroxycorticosterone (18-OH-B). 2. Of 224 patients with essential hypertension and normal or low plasma renin activity 18 had an elevated free aldosterone and/or tetrahydroaldosterone excretion without increased aldosterone-18-glucuronide. These cases may represent early...