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Keywords: 20-hydroxyeicosatetraenoic acid (20-HETE)
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Articles
Role of the CYP4A/20-HETE pathway in vascular dysfunction of the Dahl salt-sensitive rat
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (2013) 124 (12): 695–700.
Published: 26 February 2013
... Journal compilation © 2013 Biochemical Society 2013 cerebral circulation cytochrome P450-4A (CYP4A) 20-hydroxyeicosatetraenoic acid (20-HETE) oxidative stress salt-sensitive vascular function 20-HETE (20-hydroxyeicosatetraenoic acid), a vasoconstrictor metabolite of arachidonic acid...
Articles
Introgression of Brown Norway CYP4A genes on to the Dahl salt-sensitive background restores vascular function in SS-5 BN consomic rats
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (2013) 124 (5): 333–342.
Published: 16 November 2012
... in the arteries of SS rats. These findings indicate that SS rats have an up-regulation of the CYP4A/20-HETE pathway resulting in elevated ROS (reactive oxygen species) and reduced NO bioavailability causing vascular dysfunction. 20-hydroxyeicosatetraenoic acid (20-HETE) cytochrome P450 4A ω-hydroxylase...
Articles
Cytochrome P450 metabolites of arachidonic acid are elevated in stroke patients compared with healthy controls
Available to PurchaseNatalie C. Ward, Kevin D. Croft, David Blacker, Graeme J. Hankey, Anne Barden, Trevor A. Mori, Ian B. Puddey, Christopher D. Beer
Journal:
Clinical Science
Clin Sci (Lond) (2011) 121 (11): 501–507.
Published: 09 August 2011
... Journal compilation © 2011 Biochemical Society 2011 acute ischaemic stroke arachidonic acid cytochrome P450 (CYP450) dihydroxyeicosatetraenoic acid (DiHETE) epoxyeicosatrienoic acid (EET) 20-hydroxyeicosatetraenoic acid (20-HETE) oxidative stress Ischaemic brain injury is thought...