... using values for these RNA catabolites. For comparison, the corresponding excretion of creatinine, which originates from the energy metabolism of muscle, and of 3-methylhistidine (m 3 His), which is an indicator of muscle protein degradation, was determined. Differences in excretion during...

...-mail [email protected] ). 10 10 2002 7 1 2003 18 2 2003 18 2 2003 © 2003 The Biochemical Society 2003 3-methylhistidine lipopolysaccharide protein metabolism starvation Clinical Science (2003) 104, 585 590 (Printed in Great Britain) 585 Measuring whole-body actin...

... 1990 © 1991 The Biochemical Society and the Medical Research Society 1991 metabolic acidosis 3-methylhistidine muscle metabolism nitrogen excretion Clinical Science (1991) 80, 457-462 457 Skeletal muscle degradation and nitrogen wasting in rats with chronic metabolic acidosis BRYAN...

... support (IVF). Non-protein calories were provided as either all d -glucose or as 50% d -glucose/50% lipid. 2. In comparison with starvation, whole-body protein breakdown, as assessed by [ 15 N]glycine, [ 13 C]leucine and urinary excretion of 3-methylhistidine (3-MH), was diminished during IVF...

...Finbarr C. Martin; Timothy J. Peters 1. Muscle protein breakdown in vivo has been studied by measurements of urinary 3-methylhistidine/creatinine ratios. No differences were found between control subjects and chronic alcoholics either with or without proximal muscle wasting or cirrhosis. 2...

...; III, malnourished, chronically infected; IV, malnourished, uninfected. 3. Urinary nitrogen excretion was highest in group I and lowest in groups III and IV. Urinary creatinine was highest in group I, but did not differ significantly in groups II, III and IV. The excretion of 3-methylhistidine closely...

...J. L. Burgoyne; F. J. Ballard; F. M. Tomas; A. Dobozy; A. H. MacLennan; A. Fitzgerald; G. W. Dahlenburg 1. Myofibrillar protein breakdown was calculated from the urinary excretion ratio of N τ -methylhistidine (3-methylhistidine) to creatinine in newborn premature and full-term infants...

...M. Zoli; G. Marchesini; Cristina Dondi; G. P. Bianchi; E. Pisi 1. The urinary excretion of 3-methylhistidine and creatinine was measured in 15 controls and in two groups of 15 patients with liver cirrhosis, with and without severe muscle wasting. All subjects were on a meat-free diet. The values...

... exercise appear to become available through a fall in whole-body protein synthesis and a rise in whole-body protein breakdown. After exercise, protein balance becomes positive through a rise in the rate of whole-body synthesis in excess of breakdown. 4. Studies of free 3-methylhistidine in muscle, plasma...

...M. Elia; A. Carter; S. Bacon; R. Smith 1. To establish whether 3-methylhistidine in food is quantitatively excreted in the urine, five normal adults on a vegetarian diet were given known amounts of 3-methylhistidine in meat or fish. The mean cumulative 5-day increment in 3-methylhistidine excretion...

... and is apparently unrelated to changes in ketone bodies and insulin. 13 3 1979 31 10 1979 © 1980 The Biochemical Society and the Medical Research Society 1980 alanine amino acids glucagon glucose insulin ketone bodies 3-methylhistidine nitrogen surgery Clinical Science (1980...

...F. J. Ballard; F. M. Tomas; L. M. Pope; P. G. Hendry; B. E. James; R. A. MacMahon 1. Myofibrillar protein degradation has been measured by the rate of 3-methylhistidine excretion in premature infants weighing between 635 g and 1295 g. Analyses were made in conjunction with 1–3 day nitrogen balance...

...F. J. Ballard; F. M. Tomas; L. M. Stern 1. Myofibrillar protein degradation has been measured in patients with Duchenne muscular dystrophy, normal boys, adult males and Duchenne carriers by the rate of 3-methylhistidine excretion after transfer of subjects to a meat-free diet. 2. Although absolute...

...F. M. Tomas; F. J. Ballard; L. M. Pope 1. Urinary excretion of 3-methylhistidine and creatinine have been measured in normal male and female humans ranging in age from pre-term neonates to 68 years to assess changes in the rate of muscle protein degradation and in muscle mass. 2. The 3...

...-methylhistidine fell to a plateau by day 5 in all subjects. Myofibrillar protein catabolic rate calculated from the mean value of 3-methylhistidine excretion from day 5 to day 10 averaged 1·21 g day −1 kg −1 body weight. The average turnover of muscle myofibrillar protein was calculated to be 2·16%/day. 3. From...

...D. H. Williamson; Rose Farrell; Alison Kerr; R. Smith 1. Urinary excretion of 3-methylhistidine, an index of the rate of muscle breakdown, has been measured during the first 7 days in patients after elective surgery or accidental injury. 2. There was no major difference between the mean daily...