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Glucocorticoids Decrease the Conversion of Thyroxine into 3,5,3′-Tri-Iodothyronine by Isolated Rat Renal Tubules
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1982) 62 (2): 215–220.
Published: 01 February 1982
... into T 3 at concentrations of 2 × 10- 4 mol/l and 2 × 10- 5 mol/l respectively. The inhibition by cortisol and dexamethasone was time dependent and was prevented by actinomycin D and progesterone, suggesting that the inhibition is mediated by an effect on nuclear transcription dependent on binding...
