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Keywords: 5-fluorouracil
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Articles
Clin Sci (Lond) (1987) 72 (6): 705–716.
Published: 01 June 1987
...J. R. Bronk; Norma Lister; Susan Lynch 1. The transport of 5-fluorouracil, uracil and thymine has been studied with isolated jejunal loops of rat small intestine. High performance liquid chromatography was used to identify the pyrimidines and measure their concentrations. 2. When the lumen of the...
Articles
Clin Sci (Lond) (1981) 61 (6): 717–722.
Published: 01 December 1981
...M. L. G. Gardner; Jane A. Plumb 1. Water absorption rates by small intestine in vitro and the incidence of diarrhoea in vivo were estimated after 5-fluorouracil was injected into rats at various times of day and night. 2. Impairment of water absorption and the incidence of diarrhoea were minimal in...
Articles
Clin Sci (Lond) (1981) 60 (6): 707–710.
Published: 01 June 1981
...Jane A. Plumb; M. L. G. Gardner 1. Rats injected intraperitoneally (i.p.) with the Tris salt of 5-fluorouracil (1.44 mmol/kg) showed severe toxic symptoms and a 15% mortality. No mortality and no obvious toxicity, apart from intestinal toxicity, resulted after injection of the sodium salt at...
Articles
Clin Sci (Lond) (1979) 56 (3): 243–249.
Published: 01 March 1979
...M. L. G. Gardner; R. C. Heading 1. Water absorption and cytoplasmic dipeptidase activities were determined in isolated rat small intestine after animals had fed on various ‘elemental’ diets or a standard rat diet and after a single injection of 5-fluorouracil. 2. Vivonex diets were associated with...
Articles
Clin Sci Mol Med (1978) 54 (4): 411–418.
Published: 01 April 1978
...M. L. G. Gardner; R. R. Samson; R. C. Heading 1. Glucose absorption, water absorption and dipeptide hydrolase activities have been determined in isolated rat small intestine at 1, 3, 5 and 21 days after a single intraperitoneal injection of 5-fluorouracil. 2. Absorption rates and enzyme activities...