... infusions of I -[ 3 H]dopa into anaesthetized intact rats and rats pretreated with the sympathetic neurotoxin, 6-hydroxydopamine. 2. In intact rats, large arteriovenous increments in plasma dopa concentrations were noted in the femoral (47%) and adrenal (141%) beds, with a small arterial-portal venous...

...A. Schömig; R. Dietz; W. Rascher; H. Ebser; U. Voss; F. Gross 1. Neonatal sympathectomy with 6 hydroxydopamine (6-OHDA) was used as a tool to assess the significance of an increased sympathetic vascular tone for the development of high blood pressure in stroke-prone spontaneously hypertensive rats...

...Kathleen H. Berecek; W. Rascher; F. Gross 1. Alterations in vascular reactivity were assessed in isolated artificially perfused kidneys from stroke-prone spontaneously hypertensive (spSH) rats at different stages of hypertension and after neonatal sympathectomy with 6-hydroxydopamine (6-OHDA). 2...

...Suzanne Oparil; Lynda Erinoff; A. Cutilletta 1. Neither nerve-growth-factor antiserum (NGFAS) administered subcutaneously nor 6-hydroxydopamine administered intraventricularly to immature spontaneously hypertensive rats (SHR) inhibited the development of the hypertensive syndrome. In contrast...

...P. J. Lewis; H. J. Dargie; C. T. Dollery 1. The mechanism by which pretreatment of rats with intracisternal 6-hydroxydopamine prevents the onset of deoxycorticosterone hypertension has been studied. 2. Rats pretreated with central 6-hydroxydopamine increase their consumption of 0.17 mol/l sodium...

... and the Medical Research Society 1973 central nervous system neurogenic hypertension renal hypertension clonidine 6-hydroxydopamine intracisternal injection Clinical Science and Molecular Medicine (1973) 45,701-709. CENTRAL A N D PERIPHERAL MECHANISMS I N THE MAINTENANCE O F EXPERIMENTAL...

...P. J. Lewis; J. L. Reid; J. P. Chalmers; C. T. Dollery 1. Depletion of brain catecholamines by injection of 6-hydroxydopamine (6-OH D) into the cisterna magna in rabbits significantly diminished the rise in arterial pressure following the wrapping of both kidneys in cellophane, 6-OHD treated...