... Society 2022 ACE inhibitor anthracycline cardiotoxicity perindopril primary cardioprotection topoisomerase II beta Anthracycline (ANT) cardiotoxicity remains one of the most significant challenges for current cardio-oncology [ 1 , 2 ]. Traditionally, the pathogenesis of ANT-induced...

... to describe how structural biology techniques like X-ray crystallography and cryo-electron microscopy have enabled remarkable discoveries into the structure–function relationship of ACE and ACE2. This, in turn, has enabled the development of ACE inhibitors for the treatment of cardiovascular disease...

... of Ang-(1–7). It is interesting that pre-treatment with A779, a selective Mas receptor antagonist, prevented the anxiolytic-like effect induced by the ACE inhibitor. In the NSF test, TGRs showed increased latency to eating, an indicative of a higher aversion in response to a new environment...

... would normally inactivate NO, or that lisinopril may increase bradykinin-mediated NO release. ACE inhibitor endothelial dysfunction smoking Correspondence: Dr R. Butler (e-mail [email protected] ). 5 3 2001 3 4 2001 The Biochemical Society and the Medical Research...