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Articles

Clopidogrel application: beyond coronary artery disease

Chunyu Zeng
Journal: Clinical Science
Clin Sci (Lond) (2010) 118 (7): 459–461.
https://doi.org/10.1042/CS20090546
Published: 12 January 2010
... ). 28 10 2009 2 11 2009 4 11 2009 4 11 2009 ADP angiotensin II clopidogrel endothelium hypertension mesenteric artery P2Y receptor Platelets, normally circulating in resting form, respond to vascular injury by adhering to the damaged vessel wall. Activation results...
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Articles

Clopidogrel, independent of the vascular P2Y 12 receptor, improves arterial function in small mesenteric arteries from AngII-hypertensive rats

Fernanda R. C. Giachini, David A. Osmond, Shali Zhang, Fernando S. Carneiro, Victor V. Lima, Edward W. Inscho, R. Clinton Webb, Rita C. Tostes
Journal: Clinical Science
Clin Sci (Lond) (2010) 118 (7): 463–471.
https://doi.org/10.1042/CS20090392
Published: 12 January 2010
...±2.8) in AngII-treated animals. Vascular expression of P2Y 12 receptor was determined by Western blot. Pharmacological characterization of vascular P2Y 12 was performed with the P2Y 12 agonist 2-MeS-ADP [2-(methylthio) adenosine 5′-trihydrogen diphosphate trisodium]. Although 2-MeS-ADP induced...
View article titled, Clopidogrel, independent of the vascular P2Y 12 receptor, improves arterial function in small mesenteric arteries from AngII-hypertensive rats
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Articles

Aspirin Does Not Affect the Flow Cytometric Detection of Fibrinogen Binding to, or Release of α-Granules or Lysosomes from, Human Platelets

Nicolas A. F. Chronos, Darren J. Wilson, Sarah L. Janes, Ronald A. Hutton, Nigel P. Buller, Alison H. Goodall
Journal: Clinical Science
Clin Sci (Lond) (1994) 87 (5): 575–580.
https://doi.org/10.1042/cs0870575
Published: 01 November 1994
...Nicolas A. F. Chronos; Darren J. Wilson; Sarah L. Janes; Ronald A. Hutton; Nigel P. Buller; Alison H. Goodall 1. Aspirin inhibits the conversion of arachidonic acid to thromboxane A 2 which reinforces the effects of weak agonists such as ADP in platelets. 2. In this study the effect of aspirin (300...
View article titled, Aspirin Does Not Affect the Flow Cytometric Detection of Fibrinogen Binding to, or Release of α-Granules or Lysosomes from, Human Platelets
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