... comparable in males and females 24 h post-IR (Pcr: P sex = 0.08, P sex*IR = 0.002; KIM-1: P sex = 0.39, P sex*IR = 0.43; tubular damage: P sex = 0.84, P sex*IR = 0.69), although the IR-induced increase in plasma creatinine was greater in males than in females. AKI HMGB1 inflammation...

... Science (2018) 132 , 2121–2133], Cui et al. examine the ability of urinary angiotensinogen (uAGT) to predict the progression of acute kidney injury (AKI) to CKD. They principally employ a murine ischaemia reperfusion injury model to study this and provide data from a small prospective study of patients...

...Yunwen Yang; Xiaowen Yu; Yue Zhang; Guixia Ding; Chunhua Zhu; Songming Huang; Zhanjun Jia; Aihua Zhang Renal hypoxia occurs in acute kidney injury (AKI) of various etiologies. Activation of hypoxia-inducible transcription factor (HIF) has been identified as an important mechanism of cellular...