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Keywords: Acute kidney injury
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Clin Sci (Lond) (2021) 135 (23): 2607–2618.
Published: 08 December 2021
...Laurie Bruzzese; Gwénaël Lumet; Donato Vairo; Claire Guiol; Régis Guieu; Alice Faure Ischaemia–reperfusion injury (IRI) is a major cause of acute kidney injury (AKI) and chronic kidney disease, which consists of cellular damage and renal dysfunction. AKI is a major complication...
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Clin Sci (Lond) (2021) 135 (20): 2341–2356.
Published: 18 October 2021
..., the increased concentration of vasoconstrictor mediators together with the preservation (and even increase) of the response to them may help to explain sepsis-induced acute kidney injury. Correspondence: Jamil Assreuy ( jamil.assreuy@ufsc.br ) 11 05 2021 24 09 2021 07 10 2021 08 10...
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Clin Sci (Lond) (2020) 134 (16): 2223–2234.
Published: 28 August 2020
... and vascular rarefaction. Mechanistically, the protective effect of miR-20a-5p on acute kidney injury (AKI) was associated with inhibition of TECs mitochondrial injury and apoptosis in vitro and in vivo . In conclusion, miR-20a-5p is enriched in hypoxia-derived tubular exosomes and protects against acute...
Includes: Supplementary data
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Clin Sci (Lond) (2020) 134 (15): 2037–2051.
Published: 07 August 2020
... products—symmetric dimethylarginine (SDMA) and asymmetric dimethylarginine (ADMA)—are involved in several renal pathological processes, including renal fibrosis, acute kidney injury (AKI), diabetic nephropathy (DN), hypertension, graft rejection and renal tumors. We aim in this review to elucidate...
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Clin Sci (Lond) (2019) 133 (9): 1031–1047.
Published: 02 May 2019
...Hitesh Soni; Dieniffer Peixoto-Neves; Michael A. Olushoga; Adebowale Adebiyi Renal vasoconstriction, an early manifestation of ischemic acute kidney injury (AKI), results in renal hypoperfusion and a rapid decline in kidney function. The pathophysiological mechanisms that underlie ischemia...
Includes: Supplementary data
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Clin Sci (Lond) (2018) 132 (16): 1725–1739.
Published: 22 August 2018
...; Denise Maria Avancini Costa Malheiros; Marlene Antonia Reis; Clarice Kazue Fujihara; Roberto Zatz; Alvaro Pacheco-Silva; Niels Olsen Saraiva Câmara; Danilo Candido de Almeida Acute kidney injury (AKI) is considered an inflammatory disease in which toll-like receptors (TLRs) signaling pathways play...
Includes: Supplementary data
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Clin Sci (Lond) (2017) 131 (14): 1617–1629.
Published: 30 June 2017
... Ortiz ( aortiz@fjd.es ) 09 01 2017 06 04 2017 07 04 2017 © 2017 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2017 acute kidney injury chronic kidney disease implementation patient outcomes prevention translational research...
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Clin Sci (Lond) (2015) 128 (11): 749–750.
Published: 17 March 2015
... medicine after renal injury. © The Authors Journal compilation © 2015 Biochemical Society 2015 acute kidney injury bone marrow renin–angiotensin system Stem and progenitor cells, either isolated from bone marrow or other tissues, have been the centre of attention since the discovery...
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Clin Sci (Lond) (2010) 119 (9): 385–394.
Published: 23 July 2010
... enzyme) and the AT 1 receptor (AngII type 1 receptor) are associated with the inflammatory process and microvascular dysfunction of AKI (acute kidney injury) induced by renal I/R (ischaemia/reperfusion). However, Ang-(1–7) [angiotensin-(1–7)], ACE2 (angiotensin I-converting enzyme 2) and the Mas receptor...