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Keywords: Alcohol-induced liver injury (ALI)
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Articles

DNMT3b-mediated methylation of ZSWIM3 enhances inflammation in alcohol-induced liver injury via regulating TRAF2-mediated NF-κB pathway

Hai-Di Li, Xin Chen, Jie-Jie Xu, Xiao-Sa Du, Yang Yang, Juan-Juan Li, Xiao-Juan Yang, Hui-Min Huang, Xiao-Feng Li, Ming-Fei Wu, Chong Zhang, Chao Zhang, Zeng Li, Hua Wang, Xiao-Ming Meng, Cheng Huang, Jun Li
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (14): 1935–1956.
https://doi.org/10.1042/CS20200031
Published: 23 July 2020
... in alcohol-induced liver injury (ALI) was found to be associated with hypermethylation. Analysis of CpG prediction indicated the presence of two methylated sites in the ZSWIM3 promoter region and methylation inhibitor and DNA methyltransferases (DNMTs)-siRNA transfection were found to restore down-regulated...
View article titled, DNMT3b-mediated methylation of ZSWIM3 enhances inflammation in alcohol-induced liver injury via regulating TRAF2-mediated NF-κB pathway
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Includes: Supplementary data