...L. F. O. Obika; J. F. Laycock 1. The cardiovascular effects of pressor doses of arginine vasopressin were examined in anaesthetized Brattleboro rats with hereditary diabetes insipidus (BDI) and normal rats of the parent Long Evans (LE) strain, either 37 or 85 days old. 2. Control mean arterial...

... pressures were reduced by captopril (given in the drinking water) in Long Evans rats and in Brattleboro rats; there was no accompanying change in heart rate. 5. Bolus administration of captopril (30 mg day −1 kg −1 ) either intragastrically or subcutaneously did not change the fluid intakes or outputs...

..., less blood had to be taken from the Brattleboro rats than from the Long Evans rats. 3. After rapid arterial haemorrhage in the absence of naloxone, blood pressure recovery was slower in Brattleboro rats than in Long Evans rats. Naloxone did not affect the response to rapid arterial haemorrhage in Long...

... difference between the systolic blood pressures of Brattleboro rats and Long Evans rats while the animals were housed in groups, although the heart rates of the Brattleboro rats were significantly higher. 3. After S days of isolation in metabolism cages, systolic blood pressure was significantly increased...