... remain poorly understood. In a recent issue of Clinical Science ( vol. 132, issue 7, 759-776 ), Wang and colleagues, highlight the important role of overactivated C-type natriuretic peptide (CNP) and natriuretic peptide receptor 2 (CNP/NPR2) system in preventing oocyte maturation and ovulation in PCOS...

...Martin G. BUCKLEY; Geraint H. JENKINS; Andrew G. MITCHELL; Magdi H. YACOUB; Donald R. J. SINGER C-type natriuretic peptide (CNP) is a potent, endothelial-derived relaxant and growth-inhibitory factor. Accelerated vascular disease is an important cause of morbidity in cardiac transplant recipients...

... between natriuretic peptides and urinary endothelin-1 was further investigated. Six healthy volunteers received, on three different occasions, increasing doses of atrial or C-type natriuretic peptide (0, 2 and 4 ;pmol·min -1 ·kg -1 for 1 ;h each), or placebo. 2. Atrial natriuretic peptide caused...

...Kazuhito Totsune; Kazuhiro Takahashi; Osamu Murakami; Fumitoshi Satoh; Masahiko Sone; Toraichi Mouri 1. C-type natriuretic peptide is a neuropeptide, which is also produced by the vascular endothelial cells. Plasma immunoreactive C-type natriuretic peptide concentrations in patients with various...