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Keywords: Cardiomyocyte Proliferation
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Clin Sci (Lond) (2022) 136 (12): 911–934.
Published: 20 June 2022
... Commons Attribution License 4.0 (CC BY) . cardiomyocyte proliferation cell cycle cyclin dependent kinases microRNA regeneration signalling Understanding the molecular pathways that underlie exit from the cell cycle may be the key to novel regenerative strategies of the human heart post...
Clin Sci (Lond) (2017) 131 (24): 2919–2932.
Published: 08 December 2017
.... Meanwhile, CGX1321 increased Ki67 + and phosphohistone H3 (PH3 + ) cardiomyocytes in culture, indicating enhanced cardiomyocyte proliferation. The mRNA microarray showed that CGX1321 up-regulated cell cycle regulating genes such as Ccnb1 and Ccne1 . CGX1321 did not alter YAP protein phosphorylation...
Includes: Supplementary data