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Keywords: Crohn's disease
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Clin Sci (Lond) (2018) 132 (11): 1155–1168.
Published: 09 June 2018
... to this work. 19 02 2018 13 03 2018 14 03 2018 14 03 2018 © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2018 Crohn’s disease inflammatory bowel disease ulcerative colitis Crohn’s disease (CD) and ulcerative colitis...
Includes: Supplementary data
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Clin Sci (Lond) (2015) 129 (12): 1107–1113.
Published: 22 October 2015
...Francesca Zorzi; Emma Calabrese; Giovanni Monteleone In Crohn's disease, one of the two major forms of inflammatory bowel diseases in human beings, persistent and chronic inflammation promotes fibrotic processes thereby facilitating formation of strictures, the most common indication for surgical...
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Clin Sci (Lond) (2015) 129 (3): 271–280.
Published: 08 May 2015
... and function, in IBD. A significant increase in IL-34 mRNA and protein expression was seen in inflamed mucosa of patients with CD (Crohn's disease) and patients with UC (ulcerative colitis) compared with the uninvolved areas of the same patients and normal controls. IL-34 was up-regulated in LPMCs (lamina...
Includes: Supplementary data
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Clin Sci (Lond) (2010) 118 (12): 707–715.
Published: 30 March 2010
...-damaging immune response in IBDs. Correspondence: Dr Giovanni Monteleone (email Gi.Monteleone@Med.uniroma2.it ). 11 1 2010 16 2 2010 25 2 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 Crohn's disease cytokine inflammatory bowel disease (IBD...
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Clin Sci (Lond) (2004) 107 (4): 331–341.
Published: 24 September 2004
... investigated the cellular and molecular mechanisms of interactions between intestinal mucosal cells and the resident luminal bacteria in healthy individuals and patients with ulcerative colitis and Crohn's disease. Mechanisms by which the intestinal mucosa is able to avoid pro-inflammatory responses...
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Clin Sci (Lond) (1998) 94 (5): 473–478.
Published: 01 May 1998
...Jack Satsangi; Miles Parkes; Derek P. Jewell; John I. Bell 1. The aetiology of the chronic inflammatory bowel diseases, Crohn's disease and ulcerative colitis, is uncertain. Studies of specific environmental factors and immune dysfunction have provided little insight into disease pathogenesis. 2...
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Clin Sci (Lond) (1993) 84 (4): 381–386.
Published: 01 April 1993
... outcome. 3. IgM, but not IgG, lipocortin-I antibody levels were elevated in patients with ulcerative colitis and Crohn's disease compared with healthy control subjects. In patients with Crohn's disease not taking corticosteroids, IgM lipocortin-I antibody levels were directly related to disease activity...
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Clin Sci (Lond) (1992) 83 (5): 623–626.
Published: 01 November 1992
.... 2. Rectal biopsies taken at colonoscopy from patients with ulcerative colitis (n = 9), patients with Crohn's disease ( n = 6) and control subjects ( n = 16) were cultured for 24 h in the presence of N -[ 3 H]acetyl-glucosamine and [ 35 S]sulphate. Mucin was then extracted and purified, and the ratio...
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Clin Sci (Lond) (1992) 82 (3): 273–275.
Published: 01 March 1992
... colitis [median 74.5 (range 17.7–450.8) pg/mg] than in patients with active Crohn's disease [10.4 (4–46.9) pg/mg; P <0.002] or in normal control subjects [10.4(4–16.6) pg/mg; P <0.002]. 3. Circulating neutrophil-activating peptide-1/interleukin-8 was generally undetectable but there were higher...
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Clin Sci (Lond) (1990) 79 (2): 175–183.
Published: 01 August 1990
... and in Crohn's disease, but not in the irritable bowel syndrome, coeliac disease in remission or ulcerative colitis. Excretion of lactose, but not raffinose, was increased in patients with mucosal lactase deficiency, whereas excretion of l-arabinose was reduced in all disease groups except ulcerative colitis. 4...
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Clin Sci (Lond) (1988) 75 (3): 277–283.
Published: 01 September 1988
...C. C. Ainley; J. Cason; L. K. Carlsson; B. M. Slavin; R. P. H. Thompson 1. The zinc contents of plasma, erythrocytes, polymorphonuclear leucocytes and mononuclear leucocytes from 18 normal control subjects, 31 patients with Crohn's disease and 15 patients with ulcerative colitis were measured. 2...
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Clin Sci (Lond) (1987) 73 (4): 361–364.
Published: 01 October 1987
...Sergio Pacheco; Keith Hillier; Colin Smith 1. Colonic mucosa from 19 patients with ulcerative colitis, eight with Crohn's disease and 14 controls were analysed for arachidonic acid (C20:4), linoleic acid (C18:2), oleic acid (C18:1), stearic acid (C18:0) and palmitic acid (C16:0). 2. Gas–liquid...
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Clin Sci (Lond) (1981) 61 (2): 229–234.
Published: 01 August 1981
...J. R. Clamp; G. Fraser; A. E. Read 1. Mucus samples obtained from colectomy colons from 10 patients with ulcerative colitis and four patients with Crohn's disease of the colon, together with samples from 10 normal postmortem colons, have been studied. 2. Two glycoprotein fractions were isolated...
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Clin Sci (Lond) (1980) 58 (4): 295–300.
Published: 01 April 1980
...A. S. Mee; D. P. Jewell 1. The activity of a specific lysosomal marker enzyme N '-acetyl-β-d-glucosaminidase has been determined fluorimetrically in the monocytes and in the serum of patients with Crohn's disease and ulcerative colitis and compared with results obtained from healthy and disease...