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I-cell disease (mucolipidosis II): Resolution of N -acetyl-β-d-glucosaminidase and α-l-fucosidase components by DEAE-cellulose chromatography

R. B. Ellis, P. Willcox, A. D. Patrick
Journal: Clinical Science
Clin Sci Mol Med (1975) 49 (6): 543–550.
https://doi.org/10.1042/cs0490543
Published: 01 December 1975
... with reports on other cases. 2. N -Acetyl-β-d-glucosaminidase was resolved into its component forms by chromatography on microcolumns of DEAE-cellulose coupled with continuous automated assay of activity in the column effluent. Cultured skin fibroblasts from three patients showed a profound deficiency...
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