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1-7 of 7
Keywords: EMT
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (2025) 139 (03): 281–286.
Published: 04 February 2025
... -/- ) engineered to homozygously lack PDCD10 showed that PDCD10 renders cells more chemoresistant to anticancer drugs. Moreover, PDCD10 promoted TGF-β1-dependent proliferation by inactivating the retinoblastoma 1 protein (pRb) via a SMAD4-dependent pathway, and TGF-β1-driven EMT by increasing ERK1/2 activation via...
Articles
In Collection
Reproductive Physiology and Disease
Enkhtuya Radnaa, Lauren Richardson, Brett Goldman, Jared K. Burks, Tuvshintugs Baljinnyam, Natasha Vora, Hui-juan Zhang, Elizabeth A. Bonney, Arum Han, Ramkumar Menon
Journal:
Clinical Science
Clin Sci (Lond) (2022) 136 (22): 1591–1614.
Published: 14 November 2022
... the human fetal membrane’s amnion epithelial cells (AEC). We created p38 KO AEC using the CRISPR/Cas9 approach and tested cell fate in response to OS on an AEC-free fetal membrane extracellular matrix (ECM). Screening using image CyTOF indicated OS causing epithelial–mesenchymal transition (EMT). Further...
Includes: Supplementary data
Articles
Chuanjian Suo, Zeping Gui, Zijie Wang, Jiajun Zhou, Ming Zheng, Hao Chen, Shuang Fei, Min Gu, Ruoyun Tan
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (1): 53–69.
Published: 05 January 2021
... ) * These authors contributed equally to this work. 12 08 2020 26 11 2020 08 12 2020 08 12 2020 © 2021 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 Bortezomib chronic allograft dysfunction EMT IκBα kidney transplantation...
Includes: Supplementary data
Articles
Xiaohong Sun, Kaipeng Huang, Xiao Haiming, Zeyuan Lin, Yan Yang, Meng Zhang, Peiqing Liu, Heqing Huang
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (13): 1573–1592.
Published: 30 June 2020
...Xiaohong Sun; Kaipeng Huang; Xiao Haiming; Zeyuan Lin; Yan Yang; Meng Zhang; Peiqing Liu; Heqing Huang Hyperglycemia-induced renal epithelial-to-mesenchymal transition (EMT) is a key pathological factor in diabetic renal tubulointerstitial fibrosis (RIF). Our previous studies have shown...
Articles
Yiting Geng, Xiao Zheng, Wenwei Hu, Qi Wang, Yanjie Xu, Wenting He, Chen Wu, Danxia Zhu, Changping Wu, Jingting Jiang
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (10): 1197–1213.
Published: 30 May 2019
... the proliferation, epithelial–mesenchymal transition (EMT), migration, and invasion of CRC cells. Hsa_circ_0009361 was identified as the sponge of miR-582 by fluorescence in situ hybridization (FISH), RNA immunoprecipitation (RIP), and luciferase reporter assays. Overexpression of hsa_circ_0009361 up-regulated...
Includes: Supplementary data
Articles
Chia-Chia Chao, Po-Chun Chen, Pei-Chen Chiou, Chin-Jung Hsu, Po-I Liu, Yi-Chen Yang, Russel J. Reiter, Shun-Fa Yang, Chih-Hsin Tang
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (5): 709–722.
Published: 15 March 2019
...Chia-Chia Chao; Po-Chun Chen; Pei-Chen Chiou; Chin-Jung Hsu; Po-I Liu; Yi-Chen Yang; Russel J. Reiter; Shun-Fa Yang; Chih-Hsin Tang The epithelial–mesenchymal transition (EMT) phenotype, whereby mature epithelial cells undergo phenotype transition and differentiate into motile, invasive cells, has...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (3): 545–550.
Published: 13 February 2019
...Ivonne Loeffler Interstitial fibrosis is a typical feature of end-stage renal diseases, regardless of the initial cause of kidney injury. Epithelial-to-mesenchymal transition (EMT) is a mechanism that is thought to play a role in generating the interstitial matrix-producing myofibroblasts...
