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Keywords: ETA antagonist
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Articles
Jörg TRENKNER, Friedrich PRIEM, Christian BAUER, Hans-Hellmut NEUMAYER, Manfred RASCHAK, Berthold HOCHER
Journal:
Clinical Science
Clin Sci (Lond) (2002) 103 (s2002): 385S–388S.
Published: 01 September 2002
... blockade on blood pressure and kidney function in spontaneously hypertensive rats (SHRs) on a high-salt diet are unknown. We treated SHRs on a 6% (w/v) NaCl sodium diet (SHR-S) for 48 weeks with the ETA antagonist LU 135252 (whose selectivity for ETA is 150 times greater than for ETB) with 10, 30...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2002) 103 (s2002): 215S–218S.
Published: 01 September 2002
... in the isovolumically beating heart. Additionally, the maximal inotropic response (LVP and dP/dtmax) to calcium stimulation was determined. To study the role of ETA receptors under these pathophysiological conditions, one group was treated with the ETA antagonist BQ 610 (0.8 lmol/l) during hypoperfusion, and compared...