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Keywords: Endoplasmic reticulum stress
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Clin Sci (Lond) (2021) 135 (21): 2467–2481.
Published: 01 November 2021
... binding protein 1 (xbp1s), a key component of endoplasmic reticulum stress (ERS), contributes to the pathogenesis of PH. Forty male SD rats were randomly assigned to four groups: Control, Monocrotaline (MCT), MCT+AAV-CTL (control), and MCT+AAV-xbp1s. The xbp1s protein levels were found to be elevated...
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Clin Sci (Lond) (2020) 134 (10): 1127–1141.
Published: 21 May 2020
.... apoptosis endoplasmic reticulum stress folic acid homocysteine melanocytes Vitiligo Vitiligo is an acquired, chronic depigmentation disorder [ 1 ]. The primary physical symptom is patchy depigmentation on the skin, the mucous membranes and occasionally in some hair bulbs, which is characterized...
Includes: Supplementary data
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Clin Sci (Lond) (2019) 133 (13): 1421–1438.
Published: 05 July 2019
... as previously described [ 29 ]. abdominal aortic aneurysm endoplasmic reticulum stress mitochondrial biogenesis oxysterols An abdominal aortic aneurysm (AAA) is defined as a focal dilation of 50 percent greater than the normal average diameter of an aorta. It is a complex disease involving...
Includes: Supplementary data
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Clin Sci (Lond) (2019) 133 (2): 167–180.
Published: 18 January 2019
...). Published by Portland Press Limited on behalf of the Biochemical Society 2019 endoplasmic reticulum stress kidney molecular chaperones systemic lupus erythematosis Systemic lupus erythematosus (SLE) is a frequently debilitating autoimmune disease mainly affecting women, with onset typically...
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Clin Sci (Lond) (2018) 132 (8): 883–899.
Published: 30 April 2018
... 2018 01 03 2018 20 03 2018 23 03 2018 © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2018 C1q/TNF-related protein 3 endoplasmic reticulum stress High-fat diet spermatogenesis silence information regulator 1...
Includes: Supplementary data
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Clin Sci (Lond) (2015) 128 (9): 559–565.
Published: 11 February 2015
... in humans. In conclusion, EGFR inhibition appears to protect mice from AAA formation induced by Ang II plus BAPN. The mechanism seems to involve suppression of vascular EGFR and ER stress. abdominal aortic aneurysm angiotensin II endoplasmic reticulum stress hypertension rupture signal...
Includes: Supplementary data
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Clin Sci (Lond) (2009) 116 (2): 99–111.
Published: 15 December 2008
... 6 2008 © The Authors Journal compilation © 2009 Biochemical Society 2009 endoplasmic reticulum stress inflammation mitochondrion obesity pancreatic β-cell Type 2 diabetes T2DM (Type 2 diabetes mellitus) in the United States and around the world has reached epidemic...