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1-15 of 15
Keywords: Exosomes
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Articles
Nathalia C. de Almeida Oliveira, Elida A. Neri, Caio M. Silva, Iuri C. Valadão, Miriam H. Fonseca-Alaniz, Camila Zogbi, Débora Levy, Sergio P. Bydlowski, Jose Eduardo Krieger
Journal:
Clinical Science
Clin Sci (Lond) (2022) 136 (17): 1281–1301.
Published: 05 September 2022
... response. Biomolecules secreted or shuttled within extracellular vesicles, such as exosomes, may participate in the concerted response. We investigated the exosome’s microRNAs due to their capacity to fine-tune gene expression, potentially affecting the multicellular repair response. We profiled...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2022) 136 (8): 579–597.
Published: 21 April 2022
... ) circadian clock exosomes keratinocytes microRNA skin wound healing 07 01 2022 01 04 2022 04 04 2022 © 2022 The Author(s). 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative...
Articles
miR-20a-5p is enriched in hypoxia-derived tubular exosomes and protects against acute tubular injury
Wenjuan Yu, Honghui Zeng, Junzhe Chen, Sha Fu, Qiuyan Huang, Yanchun Xu, Anping Xu, Hui-yao Lan, Ying Tang
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (16): 2223–2234.
Published: 28 August 2020
...Wenjuan Yu; Honghui Zeng; Junzhe Chen; Sha Fu; Qiuyan Huang; Yanchun Xu; Anping Xu; Hui-yao Lan; Ying Tang Exosomes have been shown to effectively regulate the biological functions of target cells. Here, we investigated the protective effect and mechanism of hypoxia-induced renal tubular epithelial...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (13): 1801–1804.
Published: 17 July 2020
... © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 cancer-associated fibroblasts Exosomes JAK2/STAT3 pathway lung cancer miR-210 The authors of the original article “miR- 210 transferred by lung cancer cell-derived exosomes may act...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (8): 955–959.
Published: 21 April 2020
...Francesco Mannavola; Gaetano Pezzicoli; Marco Tucci Exosomes (Exo) have emerged as potent amplifiers of pro-tumorigenic signals to distant cells. The knowledge of their role in colorectal cancer (CRC) is continuously up-growing, although their contribution to metastasis remains largely unclear. Liu...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (7): 807–825.
Published: 09 April 2020
...Junqiang Fan; Guanxin Xu; Zhibo Chang; Ling Zhu; Jie Yao It has been generally believed that cancer-associated fibroblasts (CAFs) have the ability to increase the process of tumor angiogenesis. However, the potential mechanisms by which cancer-derived exosomes in lung cancer (LC) remains...
Includes: Supplementary data
Articles
Suchismita Dutta, Andrew Lai, Katherin Scholz-Romero, Muhammad J. A. Shiddiky, Yusuke Yamauchi, Jay S. Mishra, Gregory E. Rice, Jon Hyett, Sathish Kumar, Carlos Salomon
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (6): 593–607.
Published: 24 March 2020
... exosome samples were processed using the Filter Aided Sample Preparation (FASP) method [ 29 ]. A total of 15 µg of exosome protein from each sample was reduced with an equal volume of lysis buffer containing 8% SDS, 100 mM Tris, pH 7.6, and 0.2 M DTT followed sonication and heating of samples at 95°C...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (2): 169–192.
Published: 23 January 2020
... stroke carotid exosomes extracellular vesicles microRNA atherosclerosis Stroke, or cerebral infarction, is the development of focal neurologic deficits secondary to disrupted blood supply to a particular area of the brain, spinal cord, or retina [ 1 , 2 ]. Strokes can be secondary...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (18): 1935–1953.
Published: 17 September 2019
...Shuming Wang; Yilin Hu; Xiurui Lv; Bin Li; Dianhua Gu; Yang Li; Yong Sun; Yang Su Circular RNAs (circRNAs) play a vital role in cancers. Accumulated evidences showed that the physiological condition of cells can be reflected by the circRNAs in the exosomes they secrete, and these exosomal circRNAs...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (14): 1629–1644.
Published: 25 July 2019
...Hui Hu; Boshi Wang; Chunyu Jiang; Ruiting Li; Jungong Zhao Background: Our previous studies observed that administration of exosomes from endothelial progenitor cells (EPC) facilitated vascular repair in the rat model of balloon injury. However, the molecular events underlying this process remain...
Includes: Supplementary data
Articles
Mona Alharbi, Andrew Lai, Dominic Guanzon, Carlos Palma, Felipe Zuñiga, Lewis Perrin, Yaowu He, John D. Hooper, Carlos Salomon
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (13): 1401–1419.
Published: 05 July 2019
...Mona Alharbi; Andrew Lai; Dominic Guanzon; Carlos Palma; Felipe Zuñiga; Lewis Perrin; Yaowu He; John D. Hooper; Carlos Salomon Exosomes are small nanovesicles that carry bioactive molecules which can be delivered to neighbouring cells to modify their biological functions. Studies have showed...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (1): 23–40.
Published: 03 January 2019
... © 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2019 adipocytes exosomes MicroRNA metabolism non-coding RNAs Obesity is a worldwide epidemic that arises as a chronic long-term imbalance between calorie intake and energy expenditure...
Articles
Soumyalekshmi Nair, Nanthini Jayabalan, Dominic Guanzon, Carlos Palma, Katherin Scholz-Romero, Omar Elfeky, Felipe Zuñiga, Valeska Ormazabal, Emilio Diaz, Gregory E. Rice, Gregory Duncombe, Thomas Jansson, Harold David McIntyre, Martha Lappas, Carlos Salomon
Journal:
Clinical Science
Clin Sci (Lond) (2018) 132 (22): 2451–2467.
Published: 30 November 2018
..., which are enriched in nanovesicles called exosomes, are important regulators of gene expression. When compared with normal pregnancies, pregnancies with gestational diabetes mellitus (GDM) are associated with skeletal muscle insulin resistance as well as increased levels of circulating placental...
Includes: Supplementary data
Articles
Shayna Sharma, Mona Alharbi, Miharu Kobayashi, Andrew Lai, Dominic Guanzon, Felipe Zuñiga, Valeska Ormazabal, Carlos Palma, Katherin Scholz-Romero, Gregory E. Rice, John D. Hooper, Carlos Salomon
Journal:
Clinical Science
Clin Sci (Lond) (2018) 132 (18): 2029–2044.
Published: 19 September 2018
... attributed to cellular changes in the microenvironment, including increased migration of mesenchymal stem cells (MSCs) and endothelial cells (ECs) to facilitate metastasis. Recently, the ability of exosomes to communicate signals between cells (and promote cancer progression) has been established...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2017) 131 (1): 1–2.
Published: 21 November 2016
... cellular organelles ER exosomes microparticles mitochondria Cellular organelles have their own critical functions. For example, mitochondria are a power source to maintain cellular and tissue energy demand. However, recent expansion of pharmacological, molecular and genetic tools have allowed us...