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Keywords: Exosomes
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Articles
Clin Sci (Lond) (2020) 134 (16): 2223–2234.
Published: 28 August 2020
...Wenjuan Yu; Honghui Zeng; Junzhe Chen; Sha Fu; Qiuyan Huang; Yanchun Xu; Anping Xu; Hui-yao Lan; Ying Tang Exosomes have been shown to effectively regulate the biological functions of target cells. Here, we investigated the protective effect and mechanism of hypoxia-induced renal tubular epithelial...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2020) 134 (13): 1801–1804.
Published: 17 July 2020
... © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 cancer-associated fibroblasts Exosomes JAK2/STAT3 pathway lung cancer miR-210 The authors of the original article “miR- 210 transferred by lung cancer cell-derived exosomes may act...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2020) 134 (8): 955–959.
Published: 21 April 2020
...Francesco Mannavola; Gaetano Pezzicoli; Marco Tucci Exosomes (Exo) have emerged as potent amplifiers of pro-tumorigenic signals to distant cells. The knowledge of their role in colorectal cancer (CRC) is continuously up-growing, although their contribution to metastasis remains largely unclear. Liu...
Articles
Clin Sci (Lond) (2020) 134 (7): 807–825.
Published: 09 April 2020
...Junqiang Fan; Guanxin Xu; Zhibo Chang; Ling Zhu; Jie Yao It has been generally believed that cancer-associated fibroblasts (CAFs) have the ability to increase the process of tumor angiogenesis. However, the potential mechanisms by which cancer-derived exosomes in lung cancer (LC) remains to be...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2020) 134 (6): 593–607.
Published: 24 March 2020
... Press Limited on behalf of the Biochemical Society 2020 exosomes hypoxia placenta preeclampsia Optimal pregnancy outcome is dependent upon successful fertilization, endometrial implantation, and placentation to support blastocyst development [ 1 ]. Extravillous trophoblast plays a...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2020) 134 (2): 169–192.
Published: 23 January 2020
... in the creation of MVB was one of the first, and to date, the best characterized mechanism for exosome biogenesis [ 127 ]. The ESCRT complex is composed of 20 proteins that form four distinct complexes, ESCRT 0–III [ 128 ]. Specifically, ESCRT III along with vacuolar protein associated sorting 4...
Articles
Clin Sci (Lond) (2019) 133 (18): 1935–1953.
Published: 17 September 2019
...Shuming Wang; Yilin Hu; Xiurui Lv; Bin Li; Dianhua Gu; Yang Li; Yong Sun; Yang Su Circular RNAs (circRNAs) play a vital role in cancers. Accumulated evidences showed that the physiological condition of cells can be reflected by the circRNAs in the exosomes they secrete, and these exosomal circRNAs...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2019) 133 (14): 1629–1644.
Published: 25 July 2019
...Hui Hu; Boshi Wang; Chunyu Jiang; Ruiting Li; Jungong Zhao Background: Our previous studies observed that administration of exosomes from endothelial progenitor cells (EPC) facilitated vascular repair in the rat model of balloon injury. However, the molecular events underlying this process remain...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2019) 133 (13): 1401–1419.
Published: 05 July 2019
...Mona Alharbi; Andrew Lai; Dominic Guanzon; Carlos Palma; Felipe Zuñiga; Lewis Perrin; Yaowu He; John D. Hooper; Carlos Salomon Exosomes are small nanovesicles that carry bioactive molecules which can be delivered to neighbouring cells to modify their biological functions. Studies have showed that...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2019) 133 (1): 23–40.
Published: 03 January 2019
... target cells but normally, they are found inside small vesicles such as exosomes [ 34–36 ]. Consequently, exosomes cargo could constitute a potential regulatory factor on recipient cells. In this context, several studies have already shown the ability of secreted miRNA-containing exosomes to modulate...
Articles
Clin Sci (Lond) (2018) 132 (22): 2451–2467.
Published: 30 November 2018
..., which are enriched in nanovesicles called exosomes, are important regulators of gene expression. When compared with normal pregnancies, pregnancies with gestational diabetes mellitus (GDM) are associated with skeletal muscle insulin resistance as well as increased levels of circulating placental...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2018) 132 (18): 2029–2044.
Published: 19 September 2018
... attributed to cellular changes in the microenvironment, including increased migration of mesenchymal stem cells (MSCs) and endothelial cells (ECs) to facilitate metastasis. Recently, the ability of exosomes to communicate signals between cells (and promote cancer progression) has been established. In the...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2017) 131 (1): 1–2.
Published: 21 November 2016
... cellular organelles ER exosomes microparticles mitochondria Cellular organelles have their own critical functions. For example, mitochondria are a power source to maintain cellular and tissue energy demand. However, recent expansion of pharmacological, molecular and genetic tools have allowed us...