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Keywords: Experimental model
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Articles
Paola Dongiovanni, Marica Meroni, Guido Alessandro Baselli, Giulia Alessandra Bassani, Raffaela Rametta, Alessandro Pietrelli, Marco Maggioni, Federica Facciotti, Valentina Trunzo, Sara Badiali, Silvia Fargion, Stefano Gatti, Luca Valenti
Journal:
Clinical Science
Clin Sci (Lond) (2017) 131 (12): 1301–1315.
Published: 07 June 2017
... to investigate the independent contribution of IR and inflammation in NAFLD-related fibrosis. To this end, we managed to dissociate these two components, that are usually intertwined in patients, in an experimental model of NASH. IR was induced by haploinsufficiency for insulin receptor (InsR+/–) [ 12 – 14...
Includes: Supplementary data
