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Keywords: Farnesoid X Receptor
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Articles
Clin Sci (Lond) (2023) 137 (7): 561–577.
Published: 13 April 2023
... and Farnesoid X Receptor (FXR) deficient mice, using obeticholic acid (OCA) as control. The effects of TUDCA on liver histological changes, transaminase level, bile acid composition, hepatocyte death, expression of Fxr and nuclear factor erythroid 2-related factor 2 (Nrf2) and target genes, as well as apoptotic...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2017) 131 (10): 951–963.
Published: 04 May 2017
... to microaspiration of bile acids. Furthermore, microaspiration of bile acids also induced p-Smad3 and farnesoid X receptor (FXR) expression in rat lungs. Our findings suggest that microaspiration of bile acids could promote the development of pulmonary fibrosis in vivo , possibly via stimulating fibrogenic mediator...
Includes: Supplementary data