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Keywords: G protein-coupled estrogen receptor
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Articles

Chronic GPER activation prompted the proliferation of ileal stem cell in ovariectomized mice depending on Paneth cell–derived Wnt3

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Jianbo Liu, Kaixuan Liu, Shiquan Chai, Runze Xu, Ying Wang, Yundi Zhang, Shuanglian Wang, Chuanyong Liu, Bing Xue
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (1): 109–127.
https://doi.org/10.1042/CS20220392
Published: 05 January 2023
...Jianbo Liu; Kaixuan Liu; Shiquan Chai; Runze Xu; Ying Wang; Yundi Zhang; Shuanglian Wang; Chuanyong Liu; Bing Xue Menopausal women often face long-term estrogen treatment. G protein-coupled estrogen receptor (GPER) expressed in intestinal crypt was activated by estrogen therapy, but it was unclear...
View articletitled, Chronic GPER activation prompted the proliferation of ileal stem cell in ovariectomized mice depending on Paneth cell–derived Wnt3
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Includes: Supplementary data
Articles

Activation of G protein–coupled estrogen receptor protects intestine from ischemia/reperfusion injury in mice by protecting the crypt cell proliferation

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Shiquan Chai, Kaixuan Liu, Wanbing Feng, Tiantian Liu, Qian Wang, Rong Zhou, Shiming Chen, Liyan Wang, Guanyu Chen, Tian Ming, Jiandong Zhao, Chuanyong Liu, Bing Xue
Journal: Clinical Science
Clin Sci (Lond) (2019) 133 (3): 449–464.
https://doi.org/10.1042/CS20180919
Published: 08 February 2019
... surgery or trauma. Estrogen exerts salutary effect on intestinal I/R injury, but the receptor type is not totally understood. We aimed to identify whether the G protein–coupled estrogen receptor (GPER) could protect the intestine against I/R injury and explored the mechanism. Adult male C57BL/6 mice were...
View articletitled, Activation of G protein–coupled estrogen receptor protects intestine from ischemia/reperfusion injury in mice by protecting the crypt cell proliferation
Open the PDF for Activation of G protein–coupled estrogen receptor protects intestine from ischemia/reperfusion injury in mice by protecting the crypt cell proliferation in another window
Includes: Supplementary data