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Keywords: G-protein-coupled receptor
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Clin Sci (Lond) (2010) 119 (9): 361–372.
Published: 23 July 2010
... © 2010 Biochemical Society 2010 calcium signalling endothelin G-protein-coupled receptor ion channel vasculature ET (endothelin)-1 is a 21-amino-acid peptide, originally characterized as an endothelium-derived constricting factor in the vasculature [ 1 , 2 ]. ET-1 also affects...
Clin Sci (Lond) (2009) 116 (7): 565–574.
Published: 02 March 2009
... clear that C-peptide binds with high affinity to cell membranes, probably to a pertussis-toxin-sensitive G-protein-coupled receptor. Subsequently, multiple signalling pathways are potently and dose-dependently activated in multiple cell types by C-peptide with the resulting activation of gene...
Clin Sci (Lond) (2009) 116 (5): 391–399.
Published: 02 February 2009
... with increased signalling via G-protein-coupled receptors. Three members of the RGS (regulator of G-protein signalling) superfamily RGS2, RGS4 and RGS5 have been implicated in the attenuation of G-protein signalling pathways in vascular and cardiac myocytes, as well as cells of the kidney and autonomic nervous...