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Keywords: GLP-1
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Articles

GLP-1 response to sequential mixed meals: influence of insulin resistance

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Eleni Rebelos, Brenno Astiarraga, Roberto Bizzotto, Andrea Mari, Maria Laura Manca, Alex Gonzalez, Armando Mendez, Claudia A. Martinez, Barry E. Hurwitz, Ele Ferrannini
Journal: Clinical Science
Clin Sci (Lond) (2017) 131 (24): 2901–2910.
https://doi.org/10.1042/CS20171409
Published: 04 December 2017
... the hypothesis that this defect may be related to altered glucagon-like peptide-1 (GLP-1) release. On consecutive days, 82 non-diabetic individuals, classified as insulin sensitive (IS, n =41) or insulin resistant (IR, n =41) by the euglycaemic clamp, were given two sequential mixed meals with standard (75 g...
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Includes: Supplementary data
Articles

The regulation of function, growth and survival of GLP-1-producing L-cells

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Rune E. Kuhre, Jens J. Holst, Camilla Kappe
Journal: Clinical Science
Clin Sci (Lond) (2016) 130 (2): 79–91.
https://doi.org/10.1042/CS20150154
Published: 04 December 2015
...Rune E. Kuhre; Jens J. Holst; Camilla Kappe Glucagon-like peptide-1 (GLP-1) is a peptide hormone, released from intestinal L-cells in response to hormonal, neural and nutrient stimuli. In addition to potentiation of meal-stimulated insulin secretion, GLP-1 signalling exerts numerous pleiotropic...
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