1-2 of 2
Keywords: GTP
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles

Mycophenolate mofetil, an inhibitor of inosine monophosphate dehydrogenase, causes a paradoxical elevation of GTP in erythrocytes of renal transplant patients

David GOLDSMITH, Elizabeth A. CARREY, Stephen EDBURY, Ryszard T. SMOLENSKI, Piotr. JAGODZINSKI, H. Anne SIMMONDS
Journal: Clinical Science
Clin Sci (Lond) (2004) 107 (1): 63–68.
https://doi.org/10.1042/CS20030331
Published: 23 June 2004
... lymphocyte IMPDH (inosine monophosphate dehydrogenase), thereby drastically decreasing GTP concentrations essential to lymphocyte proliferation in vitro and in vivo . Erythrocyte GTP concentrations are commonly elevated in severe renal disease, but normalize following successful engraftment. Consequently...
View article titled, Mycophenolate mofetil, an inhibitor of inosine monophosphate dehydrogenase, causes a paradoxical elevation of <span class="search-highlight">GTP</span> in erythrocytes of renal transplant patients
Open the PDF for Mycophenolate mofetil, an inhibitor of inosine monophosphate dehydrogenase, causes a paradoxical elevation of <span class="search-highlight">GTP</span> in erythrocytes of renal transplant patients in another window
Articles

Mycophenolate mofetil treatment following renal transplantation decreases GTP concentrations in mononuclear leucocytes

Piotr JAGODZINSKI, Slawomir LIZAKOWSKI, Ryszard T. SMOLENSKI, Ewa M. SLOMINSKA, David GOLDSMITH, H. Anne SIMMONDS, Boleslaw RUTKOWSKI
Journal: Clinical Science
Clin Sci (Lond) (2004) 107 (1): 69–74.
https://doi.org/10.1042/CS20030332
Published: 23 June 2004
... monophosphate dehydrogenase), the enzyme playing a crucial role in GTP biosynthesis. However, the exact metabolic changes induced by inhibition of IMPDH in target cells of the immune system have been the subject of recent debate. The aim of the present study was to evaluate whether MMF treatment produced...
View article titled, Mycophenolate mofetil treatment following renal transplantation decreases <span class="search-highlight">GTP</span> concentrations in mononuclear leucocytes
Open the PDF for Mycophenolate mofetil treatment following renal transplantation decreases <span class="search-highlight">GTP</span> concentrations in mononuclear leucocytes in another window