... biomarker cancer cardiovascular disease chronic disease Gilbert's syndrome The formation, metabolism and excretion of bile pigments, including orange-coloured bilirubin and green biliverdin, have been comprehensively reported and discussed in the literature for some decades. These reports have...

...Marlies Wallner; Rodrig Marculescu; Daniel Doberer; Michael Wolzt; Oswald Wagner; Libor Vitek; Andrew C. Bulmer; Karl-Heinz Wagner Recent epidemiological and clinical data show protection from CVD (cardiovascular disease), all-cause mortality and cancer in subjects with GS (Gilbert's syndrome...

... subjects with Gilbert's syndrome and 35 control subjects of both sexes. 2. Both the plasma disappearance rate and the unconjugated hyperbilirubinaemia after RSV administration were higher ( P <0.001) in Gilbert's syndrome. Females, both normal and with the syndrome, showed a significantly shorter t 1/2...

...Klaus Kutz; Harald Kandler; Roland Gugler; Johan Fevery 1. Clofibrate (20 mg day −1 kg −1 body weight) given orally for 2 weeks to 18 subjects with Gilbert's syndrome reduced the total serum bilirubin concentration from 44.4 (22.1–71.7) μmol/l (median, range) to 15.0 (7.9–28.9) μmol/l, mainly...

... with the effect of caloric restriction alone. 2. In normal individuals ( n = 10) the rise of plasma bilirubin was comparable after the two trials. In patients with Gilbert's syndrome ( n = 18), bilirubin concentration rose to a much greater extent during the caloric restriction as compared with controls...

...M. L. Zeneroli; V. Piaggi; C. Cremonini; C. Gozzi; E. Ventura 1. The kinetics of non-radioactive bilirubin were investigated in 100 patients with chronic non-haemolytic unconjugated hyperbilirubinaemia and in nine normal volunteers. 2. The patients with Gilbert's syndrome were divided on the basis...

...C. A. Goresky; Ellen R. Gordon; E. A. Shaffer; P. Paré; D. Carassavas; A. Aronoff 1. Intravenous doses of bilirubin (3.4 μmol/kg) were given to normal subjects and patients with Gilbert's syndrome. Both groups displayed an identical initial disappearance of a substantial proportion of the bilirubin...

...L. Okolicsanyi; O. Ghidini; R. Orlando; S. Cortelazzo; G. Benedetti; R. Naccarato; P. Manitto 1. The kinetics of the plasma disappearance of bilirubin (2 mg/kg intravenously) were studied in 106 patients with Gilbert's syndrome and in 13 normal subjects. 2. All patients had significant decreases...

...M. Black; J. Fevery; D. Parker; J. Jacobson; Barbara H. Billing; E. R. Carson 1. The clearance of a tracer dose of [ 14 C]bilirubin from the plasma was studied in patients with Gilbert's syndrome, congenital non-haemolytic jaundice, haemolytic jaundice and in normal subjects. Clearance...