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Keywords: HMGB1
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (2024) CS20241144.
Published: 23 September 2024
... activity of CD4+ T cells. Furthermore, IFN-γ induced the nuclear-to-cytoplasm translocation and autophagy-dependent degradation of p53 in CD4+ T cells. The translocation and autophagic degradation of p53 were contingent upon HMGB1, which underwent upregulation and translocation from the nucleus...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (13): 1751–1762.
Published: 10 July 2020
... of DAMPs to IR injury in females is unknown. The goal of the current study was to test the hypothesis that males have greater increases in the DAMP high-mobility group box 1 (HMGB1), worsening injury compared with females. Thirteen-week-old male and female spontaneously hypertensive rats (SHR) were...
